PerkinElmer

Biotherapeutics Research

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Biotherapeutics allow researchers to explore new mechanisms for the treatment of a variety of conditions. Our biotherapeutics research products are designed for consistent and reproducible results, and are a component of GLP-compliant processes in the world's leading pharmaceutical, biotechnology and contract research organizations.

Effective biotherapeutic workflows make use of our portfolio of assays and reagents, multimode plate readers, instrumentation, automation solutions, informatics, and technical expertise.

Our biotherapeutics products include:

  • LANCE® TR-FRET technology for Fc-receptor binding and isotyping
  • AlphaLISA® isotyping, Fc-receptor binding, and bioprocess contaminant detection kits
  • DELFIA® (dissociation-enhanced lanthanide fluorescence immunoassay) TRF technology
  • Multimode plate readers
  • Cellular, tissue, and in vivo imaging systems

Accelerate the development and marketability of your biotherapeutic drugs while still meeting stringent regulatory demands. With our technology and guidance, numerous biotherapeutic drugs have been approved for the treatment of cancer, inflammatory disease, and several rare diseases.

For Research Use Only. Not for diagnostic procedures.

Target Identification
Target Identification

Target Identification

Identify relevant disease targets during the early stages of discovery for new biotherapeutics. Avoid latent failures downstream by thorough validation of each target. We provide the capability for the most accurate prediction of target relevance in human disease through a combination of in in vitro and in vivo approaches.
  • Cellular imaging for in vitro target validation
  • In vivo imaging for target discovery
  • Tissue imaging for ex vivo target validation
Protein Antibody
Protein Antibody

Cloning and Expression

We offer a range of microfluidic, ELISA-alternative, imaging, informatics, detection and automation solutions that simplify workflow and improve the quality of data generated at every stage in the cloning and expression process:
  • Clone Selection
  • Protein Purification
  • Functional Screening
  • Bioanalytical Characterization
General laboratory
General laboratory

Safety and Preclinical

Accurately quantify anti-drug antibodies (ADA) and pharmacokinetics (PK) / pharmacodynamics (PD) through high quality, reproducible test data. Whether your research involves monoclonal antibodies (mAb) or proteins and peptides, our wide portfolio of immunogenicity, neutralizing antibody (NAb) and PD/PK testing solutions can streamline your workflow.
Pipetting
Pipetting

Manufacturing and QC

Identify process and product related impurities to ensure they do not compromise the quality or safety of your biotherapeutics or vaccine research.

LabChip® microfluidic technology provides rapid and reproducible purity analysis for therapeutic proteins and detection and visualization of low concentration impurity peaks down to 5 ng/µL accelerating manufacturing and QC processes.

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Product Type
  • Accessories (38)
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Antibody Conjugates
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  • Anti-mouse IgG1 (1)
  • Anti-mouse IgG2a (1)
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  • Human Fc-fragment (1)
Application
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  • DNA/RNA Quantitation (1)
  • DNA/RNA Quantitation and QC (2)
  • Isotyping (11)
  • Kinase (8)
  • Protein Analysis (8)
  • Protein Analysis & Detection (95)
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Assay points(200-50,000)
  • 100 (20)
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Assay Target
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  • MEK1 (2)
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  • Residual Protein A (1)
  • S6RP (1)
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  • Transferrin (1)
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Assay Target Class
  • Antibody (39)
  • DNA (4)
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  • Peptide (1)
  • Phosphoprotein (8)
  • Protein (16)
Automation Compatible
  • Yes (107)
Depth
  • 33.0 in (2)
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Detection Method
  • Absorbance (5)
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  • Image-based Cytometry (1)
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  • Luminescence (5)
  • Time-Resolved Fluorescence (TRF) (31)
  • TR-FRET (25)
  • Transmission (2)
Experimental Type
  • In vitro (90)
Format
  • Microfluidics (2)
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Imaging Modality
  • High Content (2)
  • microCT Imaging (1)
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Maximum Temperature (Celsius)
  • 40-50 (2)
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Model Compatible With
  • Labchip DropletQuant NNA (2)
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Sample Type
  • DNA / RNA (2)
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Target Species
  • Bovine (8)
  • CHO (1)
  • Human (50)
  • Mouse (9)
  • Rabbit (2)
Therapeutic Area
  • Biologics/Bioprocess (67)
  • Inflammation (2)

"Biotherapeutics Research" 1-50 of 188 Products and Services

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EnSight multimode plate-reader

EnSight Multimode Plate Reader

The EnSight multimode plate reader combines labeled, label-free* & image-based cytometry technologies in a single benchtop platform. Imaging & online data analysis is fast: a 384-well plate can be imaged in less than 5 mins. The system’s modular design, combined with workflow-based Kaleido data acquisition & analysis software, gives a truly versatile plate reader that gets users productive quickly.

*Label free detection module of EnSight Plate Reader is available outside the EU. Please contact your local representative for further details.

EnVision_Alone_Left_Angle

EnVision 2105 Multimode Plate Reader

The EnVision 2105 multimode plate reader provides exceptional speed, ultra-high throughput, and maximum sensitivity across all detection technologies. Tried and tested, the EnVision microplate reader gives you robust performance and reliable data for high throughput screening, time after time.

The EnVision 2105 model delivers even higher sensitivity for time-resolved fluorescence (TRF) applications, and the Enhanced Security software option includes tools to facilitate 21 CFR Part 11 compliance for integration into regulated environments (GxP). In addition, the Alpha 775 laser module is designed for plant assays.

Opera Phenix High-Content Screening System

The Opera Phenix High Content Screening System is the premier confocal solution for today's most demanding high content applications. Drawing on over a decade of experience with the industry-leading Opera® High Content Screening System, the Opera Phenix is designed for high-throughput, phenotypic screening and assays involving complex disease models, such as live cells, primary cells and microtissues.

ViewLux uHTS Microplate Imager

The ViewLux® is the gold standard, ultra high-speed microplate imager, ideal for high throughput screening of compound libraries requiring the ultimate in speed, reliability and high quality data.

The ViewLux uHTS microplate imager is available outside the EU. Please contact your local representative to discuss alternative products.

IVIS SpectrumCT 2D/3D Optical/CT In Vivo Imaging System

IVIS SpectrumCT In Vivo Imaging System

The IVIS® SpectrumCT preclinical in vivo imaging system expands upon the versatility and advanced optical feature sets of the IVIS platform integrated with low dose microCT to support longitudinal imaging.
LabChip GXII Touch System

LabChip GXII Touch Protein Characterization System

The LabChip® GXII Touch protein characterization system provides the complete solution for reproducible quantitation, molecular weight sizing and percent purity analysis of protein samples. Leveraging microfluidic electrophoretic separation technology, the LabChip® GXII Touch system enables rapid characterization with minimal sample preparation setup and sample input volume.
IVIS SpectrumBL High Throughput Optical Imaging System

IVIS SpectrumBL High-Throughput In Vivo Optical Imaging System

The IVIS® SpectrumBL is an advanced high-throughput 2D and 3D optical imaging system designed to improve quantitative outcomes of bioluminescent, chemiluminescent and Cerenkov in vivo imaging.
Operetta CLS High Content Analysis Instrument

Operetta CLS High-Content Analysis System

Uncover deep biological understanding in your everyday assays and innovative applications using the Operetta CLS high-content analysis system. Featuring a unique combination of technologies, the system delivers all the speed, sensitivity and resolution you need to reveal fine sub-cellular details. And with our simple, powerful Harmony 4.5 software, Operetta CLS lets you find even subtle phenotypic changes.
IVIS SpectrumBL High Throughput Optical Imaging System

IVIS Spectrum In Vivo Imaging System

The IVIS® Spectrum in vivo imaging system uses a novel patented optical imaging technology to facilitate non-invasive longitudinal monitoring of disease progression, cell trafficking and gene expression patterns in living animals.
IVIS Lumina HT High Throughput Benchtop 2D Optical Imaging System

IVIS Lumina III In Vivo Imaging System

The IVIS® Lumina Series III brings together years of leading optical imaging technologies into one easy to use and exquisitely sensitive bench-top system.
VictorX_ImageA_320px

VICTOR Multilabel Plate Reader

The VICTOR Multilabel plate reader has been replaced by the VICTOR Nivo multimode plate reader. Please contact your local representative for further information, or visit the VICTOR Nivo product page (Part Number - HH35000500).

EnSpire Alpha Plate Reader

The EnSpire Alpha Plate Reader provides proven Alpha technology to your lab at an affordable price and from the Alpha detection leader.

EnSpire Plate Reader is available outside the EU. Please contact your local representative for further details.

JANUS G3 Btx Pro-Plus

JANUS G3 BioTx Pro Plus Workstation

The JANUS® G3 Bio Tx Pro Plus offers full walk-away automation for high-throughput process development, enabling more data from precious starting materials and limited resources.
JANUS G3 BioTx Pro Workstation

JANUS G3 BioTX Pro Workstation

The affordable and compact JANUS® G3 BioTx Pro Automated Workstation enables consistent, time-saving small-scale protein purification and sample preparation for analytical protein characterization required to support quality by design experimentation in both upstream and downstream processes.

Ideal Workstation for:

  • Expression optimization
  • Cell line selection
  • Purification process development
  • Bioanalytical sample preparation
IVIS Lumina HT High Throughput Benchtop 2D Optical Imaging System

IVIS Lumina LT In Vivo Imaging System

The IVIS® Lumina LT Series III pre-clinical in vivo imaging system offers the industries most sensitive benchtop platform at an entry level price.

EnSpire Multimode Plate Reader

EnSpire® Multimode Plate Reader is designed to meet the demands of multi-user research environments, providing high performance technology and flexibility for a range of applications without compromising sensitivity. Combine this with our expertise and portfolio of reagents, PerkinElmer offers an unrivaled solution to your application needs.

EnSpire Plate Reader is available outside the EU. Please contact your local representative for further details.

IVIS Lumina XRMS 2D Optical Imaging System with Integrated X-ray

IVIS Lumina XRMS In Vivo Imaging System

Industry leading Fluorescence, Bioluminescence and X-Ray Imaging - All-In-One benchtop instrument! The IVIS® Lumina XRMS (x-ray multi-species optical imaging system) adds to the versatility of the IVIS Lumina XR by offering the flexibility to image large animals up to 500 grams with precise optical and X-Ray overlay.
AlphaLISA SureFire Ultra kits

Phospho-SLP-76 (Ser376) AlphaLISA SureFire Ultra Assay Kit

The AlphaLISA® SureFire® Ultra™ p-SLP-76 (Ser376) HV (high volume) assay is a sandwich immunoassay for quantitative detection of phospho-SLP-76 (phosphorylated on Ser376) in cellular lysates using Alpha no-wash technology.
Price Range : 316.00 GBP - 18330.00 GBP
AlphaLISA SureFire Ultra kits

Phospho-GSK-3β (Ser9) AlphaLISA SureFire Ultra Assay Kit

The AlphaLISA® SureFire® Ultra™ p-GSK-3β (Ser9) assay is a sandwich immunoassay for quantitative detection of endogenous GSK-3β phosphorylated at Ser9 in cellular lysates using Alpha Technology.
Price Range : 316.00 GBP - 18330.00 GBP
AlphaLISA immunoassay kits

FCGR3A/CD16a (176Val/V158) AlphaLISA Binding Kit

This kit is designed for the detection of binding activity between human FCGR3A (176Val) and human IgG Fc fragment using a homogeneous AlphaLISA® assay (no wash steps). This assay can facilitate the design and development of antibody therapetics by using competitive binding.
Price Range : 449.00 GBP - 6860.00 GBP

Anti-bovine IgG AlphaLISA Acceptor Beads

AlphaLISA Acceptor beads conjugated to anti-bovine IgG (total) antibody.
Price Range : 535.00 GBP - 18100.00 GBP

Anti-bovine IgG2 AlphaLISA Acceptor Beads

AlphaLISA Acceptor beads conjugated to anti-bovine IgG2 antibody. These beads can be used to capture bovine IgG2 antibodies.
Price Range : 535.00 GBP - 18100.00 GBP

Anti-Mouse IgG3 (isotyping) AlphaLISA Acceptor beads

AlphaLISA® Acceptor beads conjugated to a anti-mouse IgG3. This bead can be used to create no-wash AlphaLISA assays for isotyping and other applications.
Price Range : 365.00 GBP - 14980.00 GBP
LANCE Detection Kit

IgA (human) LANCE Ultra TR-FRET Detection Kit

The LANCE® Ultra Human IgA Detection Kit is designed for detection and quantitation of human immunoglobulin A in buffered solution and cell culture media using a homogeneous TR-FRET (no-wash steps, no separation steps) assay.
Price Range : 514.00 GBP - 6860.00 GBP

C-peptide (human) AlphaLISA Kit

AlphaLISA® no-wash immunoassay kit for detection of human C-peptide (human connecting peptide) in serum, buffered solution or cell culture medium.
Price Range : 954.00 GBP - 6340.00 GBP
Protein

Host Cell Residual DNA standard (LANCE)

DNA standard, for use in running standard curves in LANCE Ultra TR-FRET assays. This standard is already provided in the LANCE Ultra Residual DNA Detection Kit, but can also be ordered separately.
List Price : 191.00 GBP

Albumin (human) AlphaLISA Detection Kit

AlphaLISA no-wash immunoassay kit for detection of human serum albumin (HSA) in urine, buffered solution, or cell culture medium.
Price Range : 1880.00 GBP - 14710.00 GBP
Reagent Kit

Protein Charge Variant Reagent Kit

The LabChip® protein charge variant kit is a microfluidic assay used to measure relative percentages of variant in recombinant monoclonal antibody samples.
List Price : 250.00 GBP
AlphaLISA immunoassay kits

FCGR1/CD64 AlphaLISA Binding Kit

This kit is designed for the detection of binding between FCGR1 (CD64) and human IgG Fc fragment using a homogeneous AlphaLISA® assay (no wash steps). This assay can facilitate the design and development of antibody therapetics by using competitive binding.
Price Range : 1370.00 GBP - 6860.00 GBP

Anti-Mouse IgM (isotyping) AlphaLISA Acceptor beads

AlphaLISA® Acceptor beads conjugated to a anti-mouse IgM. This bead can be used to create no-wash AlphaLISA assays for isotyping and other applications.
Price Range : 365.00 GBP - 14980.00 GBP
AlphaLISA SureFire Ultra kits

Phospho-MEK1 (Ser218/222) AlphaLISA SureFire Ultra Assay Kit

The AlphaLISA® SureFire® Ultra™ p-MEK1 (Ser218/222) HV (high volume) assay is a sandwich immunoassay for quantitative detection of phospho-MEK1 (phosphorylated on Ser218/222) in cellular lysates using Alpha no-wash technology.
Price Range : 316.00 GBP - 18330.00 GBP

Anti-Human IgG3 AlphaLISA Acceptor Beads

AlphaLISA® Acceptor beads conjugated to a anti-human IgG3. This bead can be used to create no-wash AlphaLISA assays for isotyping and other applications.
Price Range : 365.00 GBP - 14980.00 GBP
LANCE Detection Kit

IgG (mouse) LANCE Ultra TR-FRET Detection Kit

The LANCE® Ultra Mouse IgG Detection Kit is designed for detection and quantitation of Mouse IgG in cell culture media using a homogeneous TR-FRET (no-wash steps, no separation steps) assay.
Price Range : 514.00 GBP - 6860.00 GBP
AlphaLISA SureFire Ultra kits

AlphaLISA SureFire Ultra p-STAT4 (Tyr693) Assay Kit

The AlphaLISA® SureFire® Ultra p-STAT4 (Tyr693) assay is a sandwich immunoassay for quantitative detection of endogenous STAT4 phosphorylated at Tyr693 in cellular lysates using Alpha Technology.
Price Range : 316.00 GBP - 18330.00 GBP
Protein

E.coli HCP, lyophilized (LANCE)

E. coli HCP standard, lyophilized, for use in running standard curves in LANCE TR-FRET no-wash detection assays. This standard is already provided in the LANCE Ultra E. coli HCP TR-FRET Detection Kit, but can be ordered separately.
List Price : 155.00 GBP
AlphaLISA immunoassay kits

Host Cell Residual DNA AlphaLISA Detection Kit

The AlphaLISA® Host Cell Residual DNA Detection Kit is designed for detection and quantitation of DNA contaminants in cell culture supernatants using a homogeneous (no-wash steps, no separation steps) assay. This kit can be used with DNA from different prokaryotic and eukaryotic species.
Price Range : 449.00 GBP - 6490.00 GBP

IgG1 (mouse) isotyping AlphaLISA Detection Kit

This AlphaLISA® immunoassay kit enables the isotyping of mouse IgG1 antibodies in cell culture media and non-mouse serum.
Price Range : 449.00 GBP - 6240.00 GBP
AlphaLISA immunoassay kits

Transferrin (human) AlphaLISA Detection Kit

The AlphaLISA® Human Transferrin Detection Kit is designed for detection and quantitation of human transferrin in cell culture medium in a homogeneous (no-wash steps, no separation steps) assay.
Price Range : 400.00 GBP - 6240.00 GBP
AlphaLISA SureFire Ultra kits

Total MEK1 AlphaLISA SureFire Ultra Assay Kit

The AlphaLISA® SureFire® Ultra™ Total MEK1 assay is a sandwich immunoassay for quantitative detection of MEK1 (both phosphorylated and non-phosphorylated) in cellular lysates using Alpha Technology. This assay is intended to be used as a normalization for phosphorylation studies.
Price Range : 316.00 GBP - 18330.00 GBP
AlphaLISA SureFire Ultra kits

AlphaLISA SureFire Ultra p-VEGF Receptor 2 (Tyr1175) Assay Kit

The AlphaLISA® SureFire® Ultrap-VEGF Receptor 2 (Tyr1175) assay is a sandwich immunoassay for quantitative detection of phospho-VEGFR Receptor 2 (phosphorylated on Tyr1175) in cellular lysates using Alpha Technology.
Price Range : 316.00 GBP - 18330.00 GBP
AlphaLISA immunoassay kits

IgG3 (mouse) isotyping AlphaLISA Detection Kit

This AlphaLISA® immunoassay kit enables the isotyping of mouse IgG3 antibodies in cell culture media and non-mouse serum.
Price Range : 449.00 GBP - 6240.00 GBP
Protein

IgG (mouse), lyophilized (LANCE)

Mouse IgG standard, lyophilized, for use in running standard curves in LANCE TR-FRET no-wash detection assays. This standard is already provided in the LANCE Ultra Mouse IgG TR-FRET Detection Kit, but can be ordered separately.
List Price : 155.00 GBP
AlphaLISA SureFire Ultra kits

AlphaLISA SureFire Ultra p-Insulin Receptor β (Tyr1150/1151) Assay Kit

The AlphaLISA® SureFire® Ultra™ p-Insulin Receptor β (Tyr1150/1151) assay is a sandwich immunoassay for quantitative detection of phospho-INSR (phosphorylated on Tyr1150/1151) in cellular lysates using Alpha Technology.
Price Range : 316.00 GBP - 18330.00 GBP
AlphaLISA immunoassay kits

IgA (mouse) AlphaLISA Detection Kit

The AlphaLISA immunoassay kit for detection and quantitation of mouse IgA in cell culture/non-mouse serum allows for fast, reproducible, and sensitive detection without the need for time-consuming wash steps or complicated assay development.
Price Range : 400.00 GBP - 6240.00 GBP

Anti-Mouse IgA AlphaLISA Acceptor Beads

AlphaLISA® Acceptor beads conjugated to a anti-mouse IgA. This bead can be used to create no-wash AlphaLISA assays for isotyping and other applications.
Price Range : 365.00 GBP - 14980.00 GBP
AlphaLISA SureFire Ultra kits

Phospho-JNK1/2/3 (Thr183/Tyr185) AlphaLISA SureFire Ultra Assay Kit

The AlphaLISA® SureFire® Ultra™ p-JNK1/2/3 (Thr183/Tyr185) HV (high volume) assay is a sandwich immunoassay for quantitative detection of phospho-JNK1/2/3 (phosphorylated on Thr183/Tyr185) in cellular lysates using Alpha no-wash technology.
Price Range : 316.00 GBP - 18330.00 GBP

FcγR2A/CD32a (167R) AlphaLISA Binding Kit

This kit is designed for the detection of binding between FCGR2A (CD32a) (167R) and human IgG Fc fragment using a homogeneous AlphaLISA® assay (no wash steps). This assay can facilitate the design and development of antibody therapeutics by using competitive binding.
Price Range : 1370.00 GBP - 6860.00 GBP

Anti-bovine IgM AlphaLISA Acceptor Beads

AlphaLISA Acceptor beads conjugated to anti-bovine IgM antibody. These beads can be used to capture bovine IgM antibodies.
Price Range : 515.00 GBP - 17400.00 GBP
AlphaLISA SureFire Ultra kits

Total STAT3 AlphaLISA SureFire Ultra Assay Kit

The AlphaLISA® SureFire® Ultra™ Total STAT3 assay is a sandwich immunoassay for quantitative detection of STAT3 (both phosphorylated and non-phosphorylated) in cellular lysates using Alpha Technology. This assay is intended to be used as a normalization for phosphorylation studies.
Price Range : 316.00 GBP - 18330.00 GBP

Anti-Mouse IgG2b (isotyping) AlphaLISA Acceptor beads

AlphaLISA® Acceptor beads conjugated to a anti-mouse IgG2b. This bead can be used to create no-wash AlphaLISA assays for isotyping and other applications.
Price Range : 365.00 GBP - 14980.00 GBP

"Biotherapeutics Research" 1-50 of 188 Products and Services

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