PerkinElmer

CNS

OF

You'll gain the greatest possible insights into central nervous system targets and disorders in vitro, in situ, and in vivo – using our broad range of products for the neurologic researcher.

Assess mechanisms of central nervous system disease in biochemical, cellular, tissue, and animal models with our biomarker detection kits, cellular and in vivo imaging systems, and tissue pathology solutions, our target-specific radiochemicals, radioligands, and receptor-transfected cell lines and cell membranes, and informatics solutions.

  • Accurately detect and quantitate biomarkers of central nervous system disease in cells, brain tissue homogenates, cerebrospinal fluid, and other sample types, using our fast, simple, pre-validated kits
  • Effectively study targeted binding using our radiolabeled ligands and steroids
  • Quantitate biomarkers in tissue samples through our industry-leading immunohistochemistry solutions
  • Probe the biological processes in animal models from molecular, functional, and anatomical perspectives with our in vivo imaging systems
  • Gain deeper insights from phenotypic analysis with our high content screening solutions
  • Make data-driven decisions for neurologic research using advanced statistics, machine learning and data analysis methods obtaining reproducible and objective results with our informatics solutions

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Product Type
  • Accessories (34)
  • Consumables (2)
  • Reagents (162)
  • Software and Informatics (7)
Application
  • cAMP (11)
  • Drug Discovery & Development (46)
  • Immunohistochemistry (IHC) (23)
  • In situ hybridization (ISH) (23)
  • Molecular Biology (14)
  • Protein Analysis & Detection (21)
Assay points(200-50,000)
  • 10000 (5)
  • 500 (15)
  • 5000 (9)
Assay Target
  • Aβ1-40 (4)
  • Aβ1-42 (2)
  • Aβ1-x (1)
  • Aβ40 (3)
  • Aβ42 (1)
  • BDNF (2)
  • EPO (1)
  • Frataxin (2)
  • GAD67 (2)
  • Tau (1)
  • TDP-43 (2)
Assay Target Class
  • Cytokine (1)
  • GPCR (80)
  • Ion channel (3)
  • Peptide (10)
  • Protein (10)
Assay Validated
  • Binding (72)
  • Calcium Fluorescence (16)
  • Calcium Luminescence (32)
  • cAMP (20)
  • Downstream Phosphorylation (5)
  • GTPγS (19)
  • Inositol Phosphate (3)
Automation Compatible
  • Yes (21)
Buffer
  • Tricine (2)
  • Tricine with stabilizer and dye (12)
Concentration
  • 10 mCi/mL (10)
  • 12.5 mCi/mL (1)
Detection Method
  • Alpha (11)
  • Chromogenic (6)
  • Fluorescence (25)
  • Radiometric (15)
  • Time-Resolved Fluorescence (TRF) (10)
  • TR-FRET (10)
Experimental Type
  • In vitro (21)
Fluorophore
  • Coumarin (1)
  • Cy3 (8)
  • Cy5 (4)
  • Fluorescein (6)
  • TMR (5)
Format
  • Microplates (21)
  • Slides (23)
Host Cell
  • 1321N1 (4)
  • CHO-K1 (65)
  • HEK293 (13)
  • L Cells (1)
  • UC11 (1)
Label Position
  • alpha (11)
  • gamma (3)
  • Nominally Labeled (1)
Nucleotide
  • ATP (3)
  • CTP (1)
  • dATP (2)
  • dCTP (2)
  • dTTP (1)
  • GTP (1)
  • UTP (4)
Product Brand Name
  • AequoScreen (14)
  • AequoZen (12)
  • AlphaLISA (11)
  • Ancillary Products (2)
  • cAMPZen (7)
  • EasyTide (7)
  • LANCE Ultra (10)
  • Membrane Target Systems (35)
  • NEN (2)
  • NEN Radiochemicals (6)
  • Opera Phenix (7)
  • Operetta (29)
  • TSA (12)
  • TSA Plus (12)
  • ValiScreen (15)
Radionuclide
  • 33P (12)
  • 35S (2)
  • 3H (1)
Radioisotope
  • H-3 (1)
  • P-33 (12)
  • S-35 (2)
Receptor Type
  • 5-Hydroxytryptamine (Serotonin) (38)
  • Adrenergic (10)
  • Cannabinoid (9)
  • Dopamine (8)
  • GABA (4)
  • Galanin (10)
  • Neurotensin (4)
  • Nicotinic (4)
  • Opioid (11)
  • Tachykinin (1)
Target Species
  • Human (19)
  • Mouse (2)
Therapeutic Area
  • Angiogenesis (9)
  • Cardiovascular (37)
  • Central Nervous System (92)
  • CNS & Neurologic (1)
  • Diabetes (10)
  • Gastrointestinal (31)
  • Inflammation (51)
  • Metabolic (30)
  • Obesity (1)
  • Pain (21)
Volume
  • 0-50 (1)
Volume Capacity
  • 150 µL (2)

"CNS" 1-50 of 205 Products and Services

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PerkinElmer

Membrane Target Systems: Serotonin 5-HT1a (human) membrane preparation

Cell membranes prepared from cells stably-transfected with human Serotonin 5-HT1a receptor, in HEK-293 cells.
List Price : 542.00 GBP

dCTP, [α-33P]- 3000Ci/mmol, 10mCi/ml

Deoxycytidine triphosphate, labeled on the alpha phosphate group with 33P.
Price Range : 352.00 GBP - 2010.00 GBP

dATP, [α-33P]- 3000Ci/mmol, 10mCi/ml

Deoxyadenosine triphosphate, labeled on the alpha phosphate group with 33P.
Price Range : 398.00 GBP - 1650.00 GBP
PerkinElmer

Membrane Target Systems: Serotonin 5HT3 (human) membrane preparation

Cell membranes prepared from cells stably-transfected with human Serotonin 5-HT3 receptor, in HEK-293 cells.
List Price : 542.00 GBP
Receptor-expressing cell lines

cAMPZen Frozen cells, Cannabinoid CB2, Human Recombinant, CHO-K1

Our frozen, irradiated cAMPZen cells express a variety of GPCRs for binding and functional assays. No cell culture is required prior to testing.
List Price : 324.00 GBP
Receptor-expressing cell lines

Cannabinoid CB1, Human Recombinant, CHO-K1 cAMPZen® Frozen cells

Our frozen, irradiated cAMPZen cells express a variety of GPCRs for binding and functional assays. No cell culture is required prior to testing.
List Price : 324.00 GBP
Receptor-expressing cell lines

ValiScreen Serotonin 5HT-2C (e) (human) cell line

Our stable recombinant ValiScreen cell lines express a variety of GPCRs for binding and functional assays.
Receptor-expressing cell lines

Serotonin 5-HT2C (edited) AequoScreen; cell line

Our stable recombinant AequoScreen cell lines express a variety of GPCRs which all couple to a calcium response. Upon GPCR stimulation and subsequent calcium binding to the aequorin oxidation of coelenterazine leads to emission of light.
Receptor-expressing cell lines

AequoZen Frozen cells, Galanin GAL1, Human Recombinant, CHO-K1

Our frozen, irradiated AequoZen cells express a variety of GPCRs which all couple to a calcium response. Upon GPCR stimulation and subsequent calcium binding to the aequorin oxidation of coelenterazine leads to emission of light. No cell culture is required prior to testing, for these frozen cells.
List Price : 514.00 GBP
TSA Cyanine 3 & 5, TMR, Fluorescein Evaluation Kit

TSA Cy 3, Cy 5, TMR, Fluorescein Evaluation Kit

TSA® Plus multi-fluorophore detection kit, for amplification of multiple signals in immunohistochemistry (IHC), immunofluorescence (IF) or in situ hybridization protocols.
List Price : 299.00 GBP
PerkinElmer

Membrane Target Systems: Cannabinoid CB2 (human) membrane preparation

Cell membranes prepared from cells stably-transfected with human Cannabinoid CB2 receptor, in HEK-293 cells.
List Price : 542.00 GBP

dCTP, [α-33P]- 3000Ci/mmol, 10mCi/ml

Deoxycytidine triphosphate, labeled on the alpha phosphate group with 33P.
Price Range : 385.00 GBP - 2040.00 GBP
PerkinElmer

Membrane Target Systems: Serotonin 5HT6 (human) membrane preparation

Cell membranes prepared from cells stably-transfected with human Serotonin 5-HT6 receptor, in HEK-293 cells.
List Price : 542.00 GBP
PerkinElmer

TSA Biotin Reagent Pack

TSA® biotin reagent pack, for amplification of signal in immunohistochemistry (IHC), immunofluorescence (IF) or in situ hybridization protocols. These reagents amplify by depositing extra biotin in the localized area of the probe or antibody.
Price Range : 794.00 GBP - 2760.00 GBP
Receptor-expressing cell lines

Cannabinoid CB1AequoScreen cell line

Our stable recombinant AequoScreen cell lines express a variety of GPCRs which all couple to a calcium response. Upon GPCR stimulation and subsequent calcium binding to the aequorin oxidation of coelenterazine leads to emission of light.
PerkinElmer

Membrane Target Systems: Serotonin 5HT7 (human) membrane preparation, in CHO-K1 cells. 400 Units.

Cell membranes prepared from CHO-K1 cells stably-transfected with human serotonin 5HT7 receptor, 400 units.
List Price : 542.00 GBP
Receptor-expressing cell lines

ValiScreen Serotonin 5HT-5A (human) cell line

Our stable recombinant ValiScreen cell lines express a variety of GPCRs for binding and functional assays.
Protein

GAD67 (human), lyophilized (LANCE)

Human GAD67 standard, for use in running standard curves in LANCE Ultra TR-FRET assays. This standard is already provided in the LANCE Ultra GAD67 Detection Kit, but can also be ordered separately.
List Price : 146.00 GBP
Receptor-expressing cell lines

ValiScreen Cannabinoid CB1 (human) cell line

Our stable recombinant ValiScreen cell lines express a variety of GPCRs for binding and functional assays.
Receptor-expressing cell lines

AequoZen FroZen cells, Serotonin 5-HT3A, Human Recombinant, HEK293

Our frozen, irradiated AequoZen cells express a variety of GPCRs which all couple to a calcium response. Upon GPCR stimulation and subsequent calcium binding to the aequorin oxidation of coelenterazine leads to emission of light. No cell culture is required prior to testing, for these frozen cells.
List Price : 514.00 GBP
AlphaLISA immunoassay kits

Aβ 1-40 (human) High Specificity AlphaLISA Detection Kit

The AlphaLISA® immunoassay kit for human Aβ40 enables the detection and quantitation of human Aβ40 in human cerebrospinal fluid and cell culture supernatants using a homogeneous AlphaLISA assay (no wash steps). The assay shows negligible cross-reactivity with other forms of Amyloid beta (i.e. Aβ1-38 and Aβ1-42).
Price Range : 1770.00 GBP - 13840.00 GBP
PerkinElmer

Membrane Target Systems: GABA B1b (human) membrane preparation, in CHO-K1 cells. 400 Units.

Cell membranes prepared from CHO-K1 cells stably-transfected with human GABA B1b receptor, 400 units.
List Price : 542.00 GBP
Receptor-expressing cell lines

ValiScreen Adrenergic alpha 2A (human) cell line

Our stable recombinant ValiScreen cell lines express a variety of GPCRs for binding and functional assays.
Receptor-expressing cell lines

Neurotensin NTS1 AequoScreen cell line

Our stable recombinant AequoScreen cell lines express a variety of GPCRs which all couple to a calcium response. Upon GPCR stimulation and subsequent calcium binding to the aequorin oxidation of coelenterazine leads to emission of light.
TSA -Plus Tetramethylrhodamine System

TSA Plus TMR

TSA® Plus tetramethylrhodamine (TMR) detection kit, for amplification of signal in immunohistochemistry (IHC), immunofluorescence (IF) or in situ hybridization protocols. This kit amplifies by depositing extra TMR in the localized area of the probe or antibody.
Price Range : 358.00 GBP - 1570.00 GBP
Receptor-expressing cell lines

cAMPZen FroZen Cells, Galanin Gal1, Human Recombinant, CHO-K1

Our frozen, irradiated cAMPZen cells express a variety of GPCRs for binding and functional assays. No cell culture is required prior to testing.
List Price : 324.00 GBP

UTP, [α-33P]- 3000Ci/mmol, 10mCi/ml

Uridine triphosphate, labeled on the alpha phosphate group with 33P.
Price Range : 352.00 GBP - 1800.00 GBP
AlphaLISA immunoassay kits

Amyloid β 1-42 (mouse/rat) AlphaLISA Detection Kit

The AlphaLISA® Mouse/Rat Amyloid beta (Aß 1-42) Detection Kit is designed for detection and quantitation of mouse or rat Aß 1-42 in serum, cerebrospinal fluid (CSF), buffered solution or cell culture medium in a homogeneous (no-wash steps, no separation steps) assay.
Price Range : 1830.00 GBP - 14280.00 GBP

UTP, [α-33P]- 3000Ci/mmol, 10mCi/ml

Uridine triphosphate, labeled on the alpha phosphate group with 33P.
Price Range : 634.00 GBP - 1960.00 GBP
Receptor-expressing cell lines

Opioid mu AequoScreen; cell line

Our stable recombinant AequoScreen cell lines express a variety of GPCRs which all couple to a calcium response. Upon GPCR stimulation and subsequent calcium binding to the aequorin oxidation of coelenterazine leads to emission of light.
Protein

Frataxin (human), lyophilized (LANCE)

Human Frataxin standard, lyophilized, for use in running standard curves in LANCE TR-FRET no-wash detection assays. This standard is already provided in the LANCE Ultra Human Frataxin TR-FRET Detection Kit, but can be ordered separately.
List Price : 151.00 GBP
AlphaLISA immunoassay kits

Amyloid β 1-40 (high specificity) (human) AlphaLISA Detection Kit

The AlphaLISA® Human Amyloid beta 1-40 (Aß 1-40) (high specificity) Detection Kit is designed for detection and quantitation of human Aß 1-40 in cerebrospinal fluid (CSF), buffered solution or cell culture medium in a homogeneous (no-wash steps, no separation steps) assay.
List Price : 1830.00 GBP
PerkinElmer

Membrane Target Systems: Serotonin 5HT1a (human) membrane preparation, in CHO-K1 cells. 400 Units.

Cell membranes prepared from cells stably-transfected with human serotonin 5HT1a receptor
List Price : 542.00 GBP
PerkinElmer

Anti-DNP AP Conjugate

Anti-DNP antibody conjugated to alkaline phosphatase
List Price : 285.00 GBP
PerkinElmer

Membrane Target Systems: Serotonin 5HT5a (human) membrane preparation

Cell membranes prepared from cells stably-transfected with human Serotonin 5-HT5a receptor, in HEK-293 cells.
List Price : 542.00 GBP
Receptor-expressing cell lines

cAMPZen Frozen cells, Serotonin 5-HT6 Human Recombinant, 1321N1

Our frozen, irradiated cAMPZen cells express a variety of GPCRs for binding and functional assays. No cell culture is required prior to testing.
List Price : 324.00 GBP
PerkinElmer

TSA Plus Fluorescein

TSA® Plus fluorescein detection kit, for amplification of signal in immunohistochemistry (IHC), immunofluorescence (IF) or in situ hybridization protocols. This kit amplifies by depositing extra fluorescein in the localized area of the probe or antibody.
Price Range : 148.00 GBP - 1570.00 GBP
Receptor-expressing cell lines

AequoZen FroZen cells, Cannabinoid CB1, Human Recombinant, CHO-K1

Our frozen, irradiated AequoZen cell lines express a variety of GPCRs which all couple to a calcium response. Upon GPCR stimulation and subsequent calcium binding to the aequorin oxidation of coelenterazine leads to emission of light. No cell culture is required prior to testing, for these frozen cells.
List Price : 514.00 GBP
Receptor-expressing cell lines

ValiScreen Serotonin 5HT-6 (human) cell line

Our stable recombinant ValiScreen cell lines express a variety of GPCRs for binding and functional assays.
Receptor-expressing cell lines

Opioid Mu (OP3) (human) ValiScreen cell line

Our stable recombinant ValiScreen cell lines express a variety of GPCRs for binding and functional assays.
PerkinElmer

Aβ(1-40) (human), lyophilized (LANCE)

Human Aβ(1-40) standard, for use in running standard curves in LANCE TR-FRET no-wash detection assays. This standard is already provided in the LANCE Ultra Human Aβ(1-40) Detection Kit, but can be ordered separately.
List Price : 151.00 GBP
Receptor-expressing cell lines

cAMPZen FroZen Cells, Dopamine D1, Human Recombinant, CHO-K1

Our frozen, irradiated cAMPZen cells express a variety of GPCRs for binding and functional assays. No cell culture is required prior to testing.
List Price : 324.00 GBP
PerkinElmer

Membrane Target Systems: GABA B1a in HEK (human) membrane preparation, in HEK-293 cells. 400 Units.

Cell membranes prepared from HEK293 cells stably transfected with human GABA B1a receptor, 400 units.
List Price : 542.00 GBP
Receptor-expressing cell lines

ValiScreen Galanin Gal1 (human) cell line

Our stable recombinant ValiScreen cell lines express a variety of GPCRs for binding and functional assays.
TSA Plus DNP (AP)System

TSA Plus DNP (AP)

TSA® Plus DNP (AP) detection kit, for amplification of signal in immunohistochemistry (IHC), immunofluorescence (IF) or in situ hybridization protocols. The deposited DNP is detected using an anti-DNP alkaline phosphatase, with appropriate substrate.
Price Range : 169.00 GBP - 402.00 GBP
PerkinElmer

Membrane Target Systems: Serotonin 5HT-6 (human) membrane preparation, in CHO-K1 cells. 400 Units.

Our Membrane Target System membranes are prepared from cells that express recombinant or endogenous receptors. Selected for optimal performance in binding assays.
List Price : 542.00 GBP
PerkinElmer

Membrane Target Systems: Nociceptin NOP (ORL1) (human) membrane preparation, in CHO-K1 cells. 400 Units.

Cell membranes prepared from CHO-K1 cells stably-transfected with human Nociceptin NOP (ORL1) receptor, 400 units.
List Price : 542.00 GBP
TSA -Plus Cyanine 5 System

TSA Plus Cyanine 5

TSA® Plus Cyanine 5 (Cy5) detection kit, for amplification of signal in immunohistochemistry (IHC), immunofluorescence (IF) or in situ hybridization protocols. This kit amplifies by depositing extra Cy5 in the localized area of the probe or antibody.
Price Range : 148.00 GBP - 1570.00 GBP

TDP-43 (human) LANCE Ultra TR-FRET Detection Kit

The LANCE® Ultra Human TDP-43 Detection Kit is designed for detection and quantitation of human TDP-43 in buffered solution and cell culture media using a homogeneous TR-FRET (no-wash steps, no separation steps) assay.
Price Range : 485.00 GBP - 6460.00 GBP

dATP, [α-33P]- 3000Ci/mmol, 10mCi/ml

Deoxyadenosine triphosphate, labeled on the alpha phosphate group with 33P.
Price Range : 398.00 GBP - 1650.00 GBP

"CNS" 1-50 of 205 Products and Services

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