PerkinElmer

Drug Discovery Reagents

OF

Drug discovery is a complex, costly, and time-consuming undertaking. And for research scientists, high-throughput screening is where the journey to discovery begins.

Your job is to move from target to hit to candidate quickly and efficiently – with as little wasted resources as possible. Our HTS screening reagents do just that, providing you with a wide range of validated reagents and kits in Alpha, LANCE®, DELFIA®, and other assay technologies.

Accelerate your workflow, while getting consistent, accurate, and physiologically relevant results.

AlphaLISA assay principle
AlphaLISA assay principle

Alpha Technology

Virtually anything can be measured with Alpha Technology quickly and easily, including enzymes, receptor-ligand interactions, low-affinity interactions, second messenger levels, DNA, RNA, proteins, protein:protein interactions, peptides, sugars and small molecules.

  • Ease-of-use: homogeneous, no-wash assay, with no separation steps
  • Fast: results in 3 hours for most applications
  • High sensitivity: detect down to femtogram levels of target
  • Large dynamic range: 4-5 logs
  • Compatible with many samples types: serum, plasma, cerbrospinal fluid (CSF), tissue extracts, cell culture supernatants, cell lysates, and more

Choose the Alpha solution that’s right for you

  • AlphaLISA® – when running large numbers of ELISA from the same sample or working with difficult matrix, serum or plasma
  • AlphaLISA SureFire Ultra and AlphaScreen SureFire – an excellent choice for studying pathways or phosphorylated proteins in whole cells, or studying endogenous receptors
  • AlphaScreen® – perfect for studying fusion-tagged proteins or protein: protein interactions, and for testing cAMP, phosphorylated peptides or samples in a simple matrix
  • Alpha Toolbox – when your target doesn’t have an off-the-shelf kit, the toolbox gives you everything you need to create your own
LANCE biomarker detection assay principle
LANCE biomarker detection assay principle

LANCE Ultra TR-FRET

From assay development to primary and secondary screening, LANCE Ultra Technology provides researchers with robust and easy-to-use assays adaptable to a variety of targets on a broad range of multimode detectors, with the fastest time-to-results in a commercially-available TR-FRET assay.

  • No-wash/separation steps
  • Homogeneous dispense-and-read technology
  • Sensitive detection
  • High reproducibility
  • Faster time-to-results
  • Easy automation
  • 384-well and 1536-well formats

LANCE and LANCE (LANthanide Chelate Excitation) Ultra are our TR-FRET (time-resolved fluorescence resonance energy transfer), homogeneous (no wash) technologies. One binding partner of interest is labeled with a donor fluorophore (a LANCE Europium chelate) and a second one is labeled with an acceptor fluorophore (ULight™ dye). Upon excitation at 320-340 nm, energy can be transferred from the donor Europium chelate to the acceptor fluorophore if sufficiently close for FRET (~10 nm). This results in the emission of light detectable at 665 nm.

DELFIA_trf
DELFIA_trf

DELFIA

DELFIA (Dissociation-Enhanced Lanthanide Fluorescence Immunoassay) is a proven, robust immunodetection platform based on time-resolved fluorescence (TRF) detection. This detection method, coupled with the unique chemical properties of lanthanide chelates, makes DELFIA a superior alternative to conventional ELISA for research, drug discovery, and clinical applications.

DELFIA offers a combination of high sensitivity, wide dynamic range and long-lasting stability that traditional ELISA cannot match. 

Reporter gene assay
Reporter gene assay

Reporter Gene Assays

Whether your assay requires the sensitivity provided by high signal intensity, or the flexibility of an extended signal half-life, PerkinElmer provides a solution. Choose from one of three luciferase detection systems: neolite, britelite plus, or steadylite plus depending on the specific requirements of your experiment.
  • No more washing – just add your lites reagent of choice, mix, incubate, and read
  • Hassle-free storage – all lites reagents are designed for extended storage at 2-8 °C (no -20 °C storage required)
  • Odor-friendly, eliminates hood work – lites products do not contain DTT and do not have the hazards and repugnant odor typical of conventional luciferase detection systems
  • Excellent Z’ values – superior S/B ratios allow for excellent Z’ values in antagonist and agonist studies
ATPlite assay principle
ATPlite assay principle

ATP Quantitation

For fast, reliable detection of ATP for cell quantitation, ATPlite 1step and ATPlite are innovative technologies that measure cell proliferation and cytotoxicity in mammalian cells based on the detection of ATP using firefly luciferase.

ATPlite 1step – Highest sensitivity

  • True “mix and measure” continuous processing
  • Ultra high sensitivity, 3 times more light output than ATPlite
  • Short equilibrium time for faster processing
  • Signal half-life of 30 minutes

ATPlite – Convenient, extended Signal

  • 2-step format, non-separation assay for time course studies; lysate can be stored frozen and tested later
  • Quantitate from <5 cells/well
  • Prolonged equilibrium time for batch processing
  • Signal half-life of 5 hours
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"Drug Discovery Reagents" 1-50 of 1249 Products and Services

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Mucin-16 (Ovarian carcinoma antigen CA125) (human) AlphaLISA Detection Kit

The AlphaLISA® Human Mucin-16 / Ovarian Carcinoma Antigen CA125 (CA125) Detection Kit is designed for detection and quantitation of human CA125 in serum, buffered solution or cell culture medium in a homogeneous (no-wash steps, no separation steps) assay.
Price Range : 954.00 GBP - 6330.00 GBP
AlphaLISA immunoassay kits

CXCL1/GROα (human) AlphaLISA Detection Kit

The AlphaLISA® Human CXCL1/GROα Detection Kit is designed for detection and quantitation of Human CXCL1/GROα in human serum, plasma, and cell culture supernatants using a homogeneous (no-wash steps, no separation steps) assay.
Price Range : 953.00 GBP - 6300.00 GBP

Cortisol (human) AlphaLISA Detection Kit

AlphaLISA no-wash immunoassay kit for detection of human cortisol in buffer or serum.
Price Range : 436.00 GBP - 6310.00 GBP

Chloramphenicol Biotin-free AlphaLISA Detection Kit

The AlphaLISA® biotin-free immunoassay kit for chloramphenicol enables the quantitative determination of chloramphenicol in buffered solution, milk and cell culture supernatants using a homogeneous AlphaLISA assay (no wash steps). The kit utilizes a Digoxigenin (DIG) / Anti-DIG interaction as opposed to the traditional Streptavidin/Biotin interaction. This enables optimal performance when working with biotin-rich media (e.g. RPMI) or samples containing endogenous biotin.
Price Range : 268.00 GBP - 6320.00 GBP
AlphaLISA immunoassay kits

C-Reactive Protein (human) AlphaLISA Detection Kit

The AlphaLISA® Human C-Reactive Protein (CRP) Detection Kit is designed for detection and quantitation of human CRP in serum, buffered solution or cell culture medium in a homogeneous (no-wash steps, no separation steps) assay.
Price Range : 954.00 GBP - 6330.00 GBP

LANCE Ultra Europium-anti-methyl-Histone H3 Lysine 9 (H3K9me2)

Europium-labeled monoclonal antibody recognizing human Histone H3 di-methylated at lysine 9 (H3K9me2). For use in LANCE® Ultra epigenetic writer and eraser assays.
Price Range : 2080.00 GBP - 5200.00 GBP
AlphaLISA immunoassay kits

MMP-12 (human) AlphaLISA Detection Kit

The AlphaLISA® immunoassay kit for human MMP-12 enables the detection and quantitation of human matrix metalloproteinase-12 in serum or cell culture medium using a homogeneous AlphaLISA assay (no wash steps). The kit was designed to detect both MMP12 and pro-MMP12.
Price Range : 280.00 GBP - 6110.00 GBP

Protein L AlphaLISA® Acceptor beads

AlphaLISA® Acceptor beads conjugated to Protein L. These beads can be used to capture antibodies that bind Protein L for AlphaLISA no-wash assays.
Price Range : 369.00 GBP - 15140.00 GBP

IL-25 (human) AlphaLISA Detection Kit

The AlphaLISA® immunoassay kit for human IL-25 enables the quantitative determination of human interleukin 25 (IL-25) in buffered solution and cell culture supernatants using a homogeneous AlphaLISA assay (no wash steps).
Price Range : 376.00 GBP - 9030.00 GBP
AlphaLisa Analyte 2

ApoC3 (human), lyophilized (AlphaLISA)

Human ApoC3 standard, for use in running standard curves in AlphaLISA assays. This standard is already provided in the AlphaLISA human ApoC3 Detection Kit, but can also be ordered separately.
List Price : 185.00 GBP
AlphaLISA Cellular Epigenetics kits

AlphaLISA Human Total Histone H2A Cell-based Assay Kit

AlphaLISA no-wash assay kit for the detection of total human Histone 2A (H2A) in cell extracts or cells in culture medium.
Price Range : 463.00 GBP - 8640.00 GBP
SureFire principle

AlphaScreen SureFire InsulinR (p-Tyr1150;Tyr1151) Assay Kit

The AlphaScreen® SureFire® p-Insulin Receptor (Tyr1150/1151) assay is a sandwich immunoassay for quantitative detection of phospho-Insulin Receptor (phosphorylated on Tyr1150/1151) in cellular lysates using Alpha Technology.
Price Range : 1030.00 GBP - 11100.00 GBP

CD80 (human) AlphaLISA Detection Kit

The AlphaLISA® immunoassay kit for human CD80 enables the quantitative determination of human cluster of differentiation 80 (CD80) in serum, buffered solution, and cell culture media using a homogeneous AlphaLISA assay (no wash steps).
Price Range : 470.00 GBP - 9030.00 GBP
AlphaLISA immunoassay kits

CXCL11 (human) AlphaLISA Detection Kit

The AlphaLISA® Chemokine (C-X-C motif) ligand 11 (CXCL11) Detection Kit is designed for detection and quantitation of Human Chemokine (C-X-C motif) ligand 11 (CXCL11) in serum, buffered solution or cell culture medium in a homogeneous (no-wash steps, no separation steps) assay.
Price Range : 954.00 GBP - 6330.00 GBP

Anti-Sheep IgG AlphaLISA® Acceptor beads

AlphaLISA® Acceptor beads conjugated to anti-sheep IgG antibody. The antibody is a rabbit polyclonal antibody that is Fc-specific. These beads can be used to capture sheep IgG antibodies for AlphaLISA no-wash assays.
Price Range : 369.00 GBP - 15140.00 GBP
AlphaLisa Analyte 2

MMP1 (human), lyophilized (AlphaLISA)

Human Matrix Metalloproteinase-1 (MMP1) standard, lyophilized, for use in running standard curves in AlphaLISA no-wash immunoassays. This standard is already provided in the AlphaLISA human MMP1 kit, but can be ordered separately.
List Price : 155.00 GBP

IL-21 (human) AlphaLISA Detection Kit

The AlphaLISA® immunoassay kit for human IL-21 enables the quantitative determination of human interleukin-12 in buffered solution and cell culture supernatants using a homogeneous AlphaLISA assay (no wash steps).
Price Range : 376.00 GBP - 9030.00 GBP
AlphaLISA immunoassay kits

Glucagon (human) AlphaLISA Detection Kit

The AlphaLISA® Glucagon Detection Kit is designed for detection and quantitation of glucagon in cell culture media, sera and plasma, in a homogeneous (no-wash steps, no separation steps) assay.
Price Range : 436.00 GBP - 6060.00 GBP
AlphaLISA immunoassay kits

CCL4/MIP-1ß (human) AlphaLISA Detection Kit

The AlphaLISA® Human C-C Motif Chemokine 4 / Macrophage Inflammatory Protein-1beta (CCL4 / MIP-1ß) Detection Kit is designed for detection and quantitation of human CCL4/MIP-1ß in serum, buffered solution or cell culture medium in a homogeneous (no-wash steps, no separation steps) assay.
Price Range : 954.00 GBP - 6330.00 GBP

LANCE cAMP Detection Kit

LANCE® TR-FRET cAMP assay kit, for Gs- and Gi-coupled GPCR functional assays.
Price Range : 100.00 GBP - 4450.00 GBP
SureFire principle

AlphaScreen SureFire MKK4 (p-Ser257;Thr261) Assay Kit

The AlphaScreen® SureFire® p-MKK4 (Ser257/Thr261) assay is a sandwich immunoassay for quantitative detection of phospho-MKK4 (phosphorylated on Ser257/Thr261) in cellular lysates using Alpha Technology.
Price Range : 936.00 GBP - 10110.00 GBP
AlphaLISA immunoassay kits

Testosterone AlphaLISA Detection Kit

The AlphaLISA® Testosterone Research Kit is designed for detection and quantitation of testosterone in serum, buffered solution or cell culture medium in a homogeneous (no-wash steps, no separation steps) assay.
Price Range : 404.00 GBP - 6310.00 GBP
PerkinElmer

DELFIA® BATDA Labeling Reagent, 50 µL

BATDA reagents for labeling cells in DELFIA time-resolved fluroescence (TRF) assays.
List Price : 111.00 GBP

MMP-8 (human) LANCE Ultra TR-FRET Detection Kit

The LANCE® Ultra Human MMP-8 Detection Kit is designed for detection and quantitation of human matrix metalloproteinase 8 in cell culture media using a homogeneous TR-FRET (no-wash steps, no separation steps) assay.
Price Range : 499.00 GBP - 6660.00 GBP
AlphaLISA assay principle

IL-6 (monkey) AlphaLISA Detection Kit, 5,000 Assay Points

The AlphaLISA® immunoassay kit for monkey IL-6 enables the quantitative determination of cynomolgus monkey interleukin-6 in serum, buffered solution, and cell culture supernatants using a homogeneous AlphaLISA assay (no wash steps).
Price Range : 376.00 GBP - 11290.00 GBP

Anti-FLAG AlphaLISA Acceptor Beads

AlphaLISA® Acceptor beads conjugated to anti-FLAG antibody. This mouse monoclonal M2 clone recognizes the FLAG sequence at the N-terminus, Met N-terminus, C-terminus, and internal sites.
Price Range : 369.00 GBP - 15140.00 GBP

CRP (rhesus) AlphaLISA Detection Kit

The AlphaLISA® immunoassay kit for rhesus C-reactive protein (CRP) enables the quantitative determination of rhesus CRP in buffered solution, cell lysates, and cell culture supernatants using a homogeneous AlphaLISA assay (no wash steps).
Price Range : 271.00 GBP - 5940.00 GBP

Myoglobin (human) AlphaLISA Detection Kit

The AlphaLISA® Human Myoglobin Detection Kit is designed for detection and quantitation of human myoglobin in serum, buffered solution or cell culture medium in a homogeneous (no-wash steps, no separation steps) assay.
Price Range : 1830.00 GBP - 14280.00 GBP
AlphaLISA immunoassay kits

MMP-7 (human) AlphaLISA Detection Kit

The AlphaLISA® immunoassay kit for human MMP7 enables the detection and quantitation of human pro- and active MMP-7 (hMMP-7) in serum, buffered solution and cell culture supernatants using a homogeneous AlphaLISA assay (no wash steps).
Price Range : 280.00 GBP - 6110.00 GBP

IL-22 (human/rat) AlphaLISA Detection kit

AlphaLISA no-wash immunoassay kit for detection and quantitation of human or rat IL-22 in serum, cell culture supernatants, and other samples.
Price Range : 436.00 GBP - 6300.00 GBP
AlphaLISA immunoassay kits

Cry1F AlphaLISA Detection Kit

The AlphaLISA® Cry1F Detection Kit is designed for detection and quantitation of Cry1F in GMO seeds, leaf, and plant extracts using a homogeneous (no-wash steps, no separation steps) assay.
Price Range : 376.00 GBP - 5840.00 GBP
AlphaLISA immunoassay kits

CD117 (human) AlphaLISA Detection Kit

The AlphaLISA® immunoassay kit for human CD117 enables the quantitative determination of human CD117 in serum, buffered solution, and cell culture supernatants using a homogeneous AlphaLISA assay (no wash steps).
Price Range : 271.00 GBP - 5940.00 GBP
SureFire principle

AlphaScreen SureFire Phospho-HSP27 (Ser82) Assay Kit

The AlphaScreen® SureFire® p-HSP27 (Ser82) assay is a sandwich immunoassay for quantitative detection of phospho-HSP27 (phosphorylated on Ser82) in cellular lysates using Alpha Technology.
Price Range : 936.00 GBP - 10120.00 GBP

LANCE Detection Buffer 10X

Detection buffer for LANCE® TR-FRET assays.
List Price : 295.00 GBP
PerkinElmer

LANCE Ultra htPA, lyophilized (0.3ug)

LANCE Ultra htPA, lyophilized (0.3ug)
List Price : 151.00 GBP

Trefoil factor 3 (human) AlphaLISA Detection Kit

The AlphaLISA® Human Trefoil Factor 3 (TFF3) Detection Kit is designed for detection and quantitation of human TFF3 in serum, buffered solution or cell culture medium in a homogeneous (no-wash steps, no separation steps) assay.
Price Range : 954.00 GBP - 6330.00 GBP

Chloramphenicol AlphaLISA Detection Kit

The AlphaLISA® immunoassay kit for Chloramphenicol enables the quantitative determination of Chloramphenicol in buffered solution, sample extracts, and cell culture supernatants using a homogeneous AlphaLISA assay (no wash steps).
Price Range : 268.00 GBP - 6320.00 GBP
SureFire principle

AlphaScreen SureFire STAT5 (p-Tyr694;Tyr699) Assay Kit 

The AlphaScreen® SureFire® p-STAT5 (p-Tyr694/699) assay is a sandwich immunoassay for quantitative detection of phospho-STAT5 (phosphorylated on Tyr694/699) in cellular lysates using Alpha Technology.
Price Range : 1030.00 GBP - 11100.00 GBP
AlphaLISA immunoassay kits

Factor VIII (human) AlphaLISA Detection Kit

The AlphaLISA® Human Factor VIII Detection Kit is designed for detection and quantitation of Human Factor VIII in human serum, plasma, and cell culture supernatants using a homogeneous (no-wash steps, no separation steps) assay.
Price Range : 404.00 GBP - 6310.00 GBP
AlphaLisa Analyte 2

IL-12 (bovine), lyophilized (AlphaLISA)

Bovine IL-12 standard, for use in running standard curves in AlphaLISA assays. This standard is already provided in the AlphaLISA bovine IL-12 Detection Kit, but can also be ordered separately.
List Price : 185.00 GBP
AlphaLISA immunoassay kits

IL-13 (porcine) AlphaLISA Detection Kit

The AlphaLISA® immunoassay kit for IL13 is designed for the quantitative determination of IL13 in porcine serum, plasma, and cell culture supernatants using a homogeneous AlphaLISA assay (no wash steps). The assay shows minimal cross-reactivity with human IL13.
Price Range : 437.00 GBP - 6490.00 GBP
Alpha donor antibody coated

Anti-Mouse IgG Alpha Donor beads

Alpha Donor beads conjugated to anti-mouse IgG antibody. This bead can be used to capture mouse IgG antibodies for Alpha no-wash protein detection, antibody detection, antibody binding, and other applications.
Price Range : 302.00 GBP - 5470.00 GBP

Anti-GFP AlphaLISA® Acceptor beads

AlphaLISA® Acceptor beads conjugated to anti-GFP antibody. The antibody is a mouse monoclonal antibody that recognizes wildtype and recombinant GFP (rGFP), and cross-reacts with eGFP. These beads can be used to capture GFP-tagged proteins for AlphaLISA no-wash assays.
Price Range : 369.00 GBP - 15140.00 GBP
AlphaLISA immunoassay kits

D-dimer (human) AlphaLISA Detection Kit

The AlphaLISA® Human D-dimer Detection Kit is designed for detection and quantitation of human D-dimer in citrate plasma, buffered solution or cell culture medium in a homogeneous (no-wash steps, no separation steps) assay. Please note the kit shows some cross-reactivity to D-monomer.
Price Range : 1830.00 GBP - 14280.00 GBP

Glutathione AlphaLISA Acceptor Beads

AlphaLISA® Acceptor beads conjugated to glutathione. These beads can be used to capture GST-tagged proteins and peptides.
Price Range : 369.00 GBP - 15140.00 GBP
AlphaLisa Analyte 2

hCG (human), lyophilized (AlphaLISA)

Human chorionic gonadotropin (hCG) standard, for use in running standard curves in AlphaLISA assays. This standard is already provided in the AlphaLISA hCG Detection Kit, but can also be ordered separately.
List Price : 185.00 GBP
AlphaLisa Analyte 2

Insulin (human), lyophilized (AlphaLISA)

Human insulin, lyophilized, 0.01 IU. Human insulin is included in the AlphaLISA® human insulin kits, but can also be ordered separately as a standalone item. One vial contains an amount of human insulin sufficient for performing 10 standard curves.
List Price : 155.00 GBP
PerkinElmer

LANCE Eu-W1024 Biotin

Europium-labeled biotin for use in LANCE® TR-FRET assays.
List Price : 593.00 GBP

Nickel Chelate AlphaLISA Acceptor Beads

AlphaLISA® Acceptor beads conjugated to nickel chelate. These beads can be used to capture His-tagged proteins and peptides.
Price Range : 369.00 GBP - 15140.00 GBP
AlphaLisa Analyte 2

Lambda light chain (human), lyophilized (AlphaLISA)

Human lambda light chain standard, for use in running standard curves in AlphaLISA assays. This standard is already provided in the AlphaLISA human lambda light chain Detection Kit, but can also be ordered separately.
List Price : 185.00 GBP

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