PerkinElmer

High Throughput and Phenotypic Screening

OF

Complete solutions for high-throughput and phenotypic screening – together, this spells discovery.

To get drugs to market that much sooner, you need to accelerate your workflow, upstream and downstream. Our screening solutions are a crucial component in that effort: State-of-the art imaging and detection instruments, assay technologies, reagents, versatile automation systems, and powerful informatics solutions working together to ensure consistent, accurate, physiologically relevant results – with one-of-a-kind analytics to wrest more meaning from your findings. Amplify your phenotypic or target-based screens to identify hits and lead compounds in small and focused or high-throughput volumes by using of complete suite of instrument, reagents and informatics solutions:

  • Screening assays for molecular targets
  • High content screening using cellular models
  • High content analysis of microtissues and 3D cell culture
  • Orthogonal testing and secondary screening
  • Selectivity screening
  • Large volume data capture and rapid analysis

High Throughput Screening
High Throughput Screening

High Throughput Screening

From validated assays to verified workflows, our HTS solutions for target-based screening enhance efficiency in your lab and confidence in your results.
Screening Data Analysis
Screening Data Analysis

Data Analysis

With the large volumes of data generated by high-throughput and phenotypic screening, you need software solutions that can aggregate and interpret your results. We offer scalable platforms that make it easy to access and manage all relevant data for enhancing the speed and efficiency in drug discovery.

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EnVision_Alone_Left_Angle

EnVision 2105 Multimode Plate Reader

The EnVision 2105 multimode plate reader provides exceptional speed, ultra-high throughput, and maximum sensitivity across all detection technologies. Tried and tested, the EnVision microplate reader gives you robust performance and reliable data for high throughput screening, time after time.

The EnVision 2105 model delivers even higher sensitivity for time-resolved fluorescence (TRF) applications, and the Enhanced Security software option includes tools to facilitate 21 CFR Part 11 compliance for integration into regulated environments (GxP). In addition, the Alpha 775 laser module is designed for plant assays.

Opera Phenix High-Content Screening System

The Opera Phenix High Content Screening System is the premier confocal solution for today's most demanding high content applications. Drawing on over a decade of experience with the industry-leading Opera® High Content Screening System, the Opera Phenix is designed for high-throughput, phenotypic screening and assays involving complex disease models, such as live cells, primary cells and microtissues.
JANUS G3 Btx Pro-Plus

JANUS G3 BioTx Pro Plus Workstation

The JANUS® G3 Bio Tx Pro Plus offers full walk-away automation for high-throughput process development, enabling more data from precious starting materials and limited resources.

EnSpire Alpha Plate Reader

The EnSpire Alpha Plate Reader provides proven Alpha technology to your lab at an affordable price and from the Alpha detection leader.

EnSpire Plate Reader is available outside the EU. Please contact your local representative for further details.

JANUS-G3-Standard-8Tip-Varispan-and-MDT-Workstation

JANUS G3 Varispan + MDT Automated Workstation

The JANUS® G3 Automated Workstation offers multiple pipetting technologies on a single instrument platform. The instrument consists of a modular platform and combines a flexible 4- or 8-tip Varispan™ arm with 96- or 384-channel Modular Dispense Technology™ (MDT) dispense head, providing an automated liquid handling solution with flexibility in throughput, plate capacity, and dynamic volume range.
EnSight multimode plate-reader

EnSight Multimode Plate Reader

The EnSight multimode plate reader combines labeled, label-free* & image-based cytometry technologies in a single benchtop platform. Imaging & online data analysis is fast: a 384-well plate can be imaged in less than 5 mins. The system’s modular design, combined with workflow-based Kaleido data acquisition & analysis software, gives a truly versatile plate reader that gets users productive quickly.

*Label free detection module of EnSight Plate Reader is available outside the EU. Please contact your local representative for further details.

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JANUS G3 MDT Automated Workstation

The JANUS® G3 MDT Automated Workstation offers multiple pipetting technologies on a single instrument platform. The instrument consists of an expanding modular platform and a 96- or 384-channel Modular Dispense Technology (MDT) dispense head, and provides an automated liquid handling solution with flexibility in throughput, plate capacity, and dynamic volume range.

ViewLux uHTS Microplate Imager

The ViewLux® is the gold standard, ultra high-speed microplate imager, ideal for high throughput screening of compound libraries requiring the ultimate in speed, reliability and high quality data.

The ViewLux uHTS microplate imager is available outside the EU. Please contact your local representative to discuss alternative products.

Operetta CLS High Content Analysis Instrument

Operetta CLS High-Content Analysis System

Uncover deep biological understanding in your everyday assays and innovative applications using the Operetta CLS high-content analysis system. Featuring a unique combination of technologies, the system delivers all the speed, sensitivity and resolution you need to reveal fine sub-cellular details. And with our simple, powerful Harmony 4.5 software, Operetta CLS lets you find even subtle phenotypic changes.

EnSpire Multimode Plate Reader

EnSpire® Multimode Plate Reader is designed to meet the demands of multi-user research environments, providing high performance technology and flexibility for a range of applications without compromising sensitivity. Combine this with our expertise and portfolio of reagents, PerkinElmer offers an unrivaled solution to your application needs.

EnSpire Plate Reader is available outside the EU. Please contact your local representative for further details.

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VICTOR Multilabel Plate Reader

The VICTOR Multilabel plate reader has been replaced by the VICTOR Nivo multimode plate reader. Please contact your local representative for further information, or visit the VICTOR Nivo product page (Part Number - HH35000500).
JANUS G3 Btx Pro-Plus

Flexible JANUS® G3 Automated Workstations

The JANUS® G3 Automated workstations include a portfolio of precision liquid handling solutions that provide adaptability in throughput, plate capacity and dynamic volume range to meet your current and future automation needs.
AlphaLISA SureFire Ultra kits

Phospho-TrkA (Tyr674/675)/phospho-TrkB (Tyr706/707) AlphaLISA SureFire Ultra Assay Kit

The AlphaLISA® SureFire® Ultra™ p-TrkA (Tyr674/675)/p-Trk-B (Tyr706/707) assay is a sandwich immunoassay for quantitative detection of phospho-TrkA (phosphorylated on Tyr674/675) and/or pTrkB (phosphorylated on residues Tyr706/707) in cellular lysates using Alpha Technology.
Price Range : 316.00 GBP - 19060.00 GBP

C-Peptide (mouse/rat) AlphaLISA Detection Kit

The AlphaLISA® Mouse/Rat Connecting Peptide (C-Peptide) Detection Kit is designed for detection and quantitation of mouse or rat C-Peptide in buffered solution in a homogeneous (no-wash steps, no separation steps) assay.
Price Range : 1880.00 GBP - 14710.00 GBP
Alpha donor antibody coated

Anti-Mouse IgG Alpha Donor beads

Alpha Donor beads conjugated to anti-mouse IgG antibody. This bead can be used to capture mouse IgG antibodies for Alpha no-wash protein detection, antibody detection, antibody binding, and other applications.
Price Range : 311.00 GBP - 5640.00 GBP
PerkinElmer

Lid-384, Clear Sterile Lid for 384-well Microplates

Sterile lids for 384-well OptiPlate, CulturPlate, and SpectraPlate microplates.
List Price : 110.00 GBP
AlphaLISA SureFire Ultra kits

AlphaLISA SureFire Ultra p-VEGF Receptor 2 (Tyr1175) Assay Kit

The AlphaLISA® SureFire® Ultrap-VEGF Receptor 2 (Tyr1175) assay is a sandwich immunoassay for quantitative detection of phospho-VEGFR Receptor 2 (phosphorylated on Tyr1175) in cellular lysates using Alpha Technology.
Price Range : 316.00 GBP - 18330.00 GBP
PerkinElmer

LANCE Ultra Europium anti-phospho-Glycogen Synthase (Ser641)

Europium-labeled rabbit polyclonal antibody recognizing human Muscle Glycogen Synthase phosphorylated at Ser641. Antibody labeled with the LANCE® Eu-W1024-ITC chelate. Sequence motif recognized: PApSVPPSPSL
Price Range : 1470.00 GBP - 4380.00 GBP
AlphaLisa Analyte 2

IL-17F (human) Iyophilized (AlphaLISA)

Human IL17F standard, lyophilized, for use in running standard curves in AlphaLISA no-wash immunoassays. This standard is already provided in the AlphaLISA IL17F Detection Kit, but can be ordered separately.
List Price : 197.00 GBP
PerkinElmer

Membrane Target Systems: Adenosine A1 (rat) membrane preparation, in CHO-K1 cells. 400 Units.

Cell membranes prepared from CHO-K1 cells stably-transfected with rat adenosine A1 receptor, 400 units.
List Price : 569.00 GBP

AlphaScreen PhosphoSensor Kit

Antibody-free assay for kinase activity via dectection of phosphorylated protein or peptide substrate.
Price Range : 248.00 GBP - 1860.00 GBP
Assay principle of Alpha Terbium SureFire Ultra assay

Total Cofilin Terbium SureFire Ultra Detection Kit

The Alpha SureFire® Ultra™ Multiplex kits allow the rapid, sensitive, and quantitative detection of two targets in each well of an assay plate. This kit can be used in combination with the AlphaLISA SureFire Ultra phospho-cofilin assay to normalize to levels of total cofilin.
Price Range : 226.00 GBP - 13610.00 GBP

AlphaScreen Omnibeads

Single bead instrument control that contains the chemistry of both Alpha Donor beads and AlphaScreen Acceptor beads.
Alpha donor antibody coated

Anti-DIG Alpha Donor beads

Alpha Donor beads conjugated to anti-DIG (digoxin) antibody. This bead can be used to capture Dig-labeled biomolecules for Alpha no-wash assays.
Price Range : 332.00 GBP - 5650.00 GBP
AlphaLISA SureFire Ultra kits

Total Cofilin AlphaLISA SureFire Ultra Detection Kit

The AlphaLISA® SureFire® Ultra Total Cofilin assay is a sandwich immunoassay for quantitative detection of cofilin (both phosphorylated and non-phosphorylated) in cellular lysates using Alpha Technology. This assay is intended to be used as a normalization for phosphorylation studies.
Price Range : 316.00 GBP - 19060.00 GBP

Deepwell LumaPlate-384, White, 60µl, Case of 50

The Deepwell LumaPlate™-384 is a solid scintillator coated, 384-well microplate that eliminates the need for adding liquid scintillation counting (LSC) cocktail. This deepwell version has a sample working volume of 100 µL.
List Price : 1490.00 GBP
Receptor-expressing cell lines

ValiScreen Melanocortin MC3 (mouse) cell line

Our stable recombinant ValiScreen cell lines express a variety of GPCRs for binding and functional assays.

Chloramphenicol Biotin-free AlphaLISA Detection Kit

The AlphaLISA® biotin-free immunoassay kit for chloramphenicol enables the quantitative determination of chloramphenicol in buffered solution, milk and cell culture supernatants using a homogeneous AlphaLISA assay (no wash steps). The kit utilizes a Digoxigenin (DIG) / Anti-DIG interaction as opposed to the traditional Streptavidin/Biotin interaction. This enables optimal performance when working with biotin-rich media (e.g. RPMI) or samples containing endogenous biotin.
Price Range : 276.00 GBP - 6510.00 GBP
AlphaLisa Analyte 2

Alpha-1 Anti-Trypsin (A1AT) (human), lyophilized (AlphaLISA)

Human A1AT standard, lyophilized, for use in running standard curves in AlphaLISA no-wash immunoassays. This standard is already provided in the AlphaLISA Human A1AT Detection Kit, but can be ordered separately.
List Price : 155.00 GBP
Assay principle of Alpha Terbium SureFire Ultra assay

Phospho-AKT (Ser473) Terbium SureFire Ultra Detection Kit

The Alpha SureFire® Ultra™ Multiplex kits allow the rapid, sensitive, and quantitative detection of two phosphoprotein targets in each well of an assay plate. This kit can be used in combination with any AlphaLISA SureFire Ultra assay to detect phospho-AKT (Ser473) in a multiplexed assay.
Price Range : 226.00 GBP - 13610.00 GBP
AlphaPlex-545-antibody-bead2

Anti-rabbit IgG AlphaPlex-545 (Tb) Acceptor Beads

AlphaPlex™-545 (Terbium) Acceptor beads conjugated to anti-rabbit IgG antibody, for use in Alpha no-wash multiplexing assays.
Price Range : 380.00 GBP - 15580.00 GBP

AlphaScreen GST Detection Kit

AlphaScreen® no-wash assay kit containing Streptavidin Donor beads and Anti-GST conjugated AlphaScreen Acceptor beads. This kit contains enough reagents to run 500 wells in 384-well format, using a 25 µL reaction volume.
Price Range : 116.00 GBP - 8900.00 GBP
SureFire principle

AlphaScreen SureFire IKKa (p-Ser176/Ser180) Assay Kit

The AlphaScreen® SureFire® p-IKKα (Ser176/180) assay is a sandwich immunoassay for quantitative detection of phospho-IKKα (phosphorylated on Ser176/180) in cellular lysates using Alpha Technology. Please note that an AlphaScreen Protein A kit, which contains the Alpha Beads necessary to run this assay, needs to be purchased separately in addition to the AlphaScreen SureFire kit.
Price Range : 1070.00 GBP - 11430.00 GBP
Assay principle of Alpha Terbium SureFire Ultra assay

Phospho-EGF Receptor (Tyr1068) Terbium SureFire Ultra Detection Kit

The Alpha SureFire® Ultra™ Multiplex kits allow the rapid, sensitive, and quantitative detection of two phosphoprotein targets in each well of an assay plate. This kit can be used in combination with any AlphaLISA SureFire Ultra assay to detect phospho-EGF Receptor (Tyr1068) in a multiplexed assay.
Price Range : 226.00 GBP - 13610.00 GBP

CHO HCP (broad reactivity) AlphaLISA Detection Kit

AlphaLISA® no-wash immunoassay kit for detection of Chinese Hamster Ovary Host Cell Proteins (CHO HCP) in buffered solution or cell culture medium.
Price Range : 954.00 GBP - 6340.00 GBP

IFN-β (human) AlphaLISA Detection Kit

The AlphaLISA® Human Interferon β (IFNβ) Detection Kit is designed for detection and quantitation of human IFNβ in serum, buffered solution or cell culture medium in a homogeneous (no-wash steps, no separation steps) assay. The analyte in this kit corresponds to the IFN-ß 1a subtype.
Price Range : 982.00 GBP - 6520.00 GBP
AlphaLISA immunoassay kits

TNFα (mouse) AlphaLISA Biotin-Free Detection Kit

The AlphaLISA Mouse TNFα Biotin-Free Detection Kit is designed for the quantitative detection of mouse TNFα in serum, cell culture medium, and other samples types using a homogeneous (no wash steps, no separation steps) assay. The biotin-free kit uses anti-DIG (anti-Digoxin) Donor beads instead of streptavidin Donor beads, which makes the kit compatible with high-biotin culture media and other sample types that contain high levels biotin (including brain/liver tissue extracts, milk and eggs).
Price Range : 417.00 GBP - 6500.00 GBP

MMP-12 (human) LANCE Ultra TR-FRET Detection Kit

The LANCE® Ultra Human MMP-12 Detection Kit is designed for detection and quantitation of Matrix metalloproteinase 12 in cell culture media using a homogeneous TR-FRET (no-wash steps, no separation steps) assay.
Price Range : 514.00 GBP - 6860.00 GBP
AlphaPlex Samarium immunoassay kits

AlphaPlex-645 (Sm) Human ICAM-1 Detection Kit

The AlphaPlex™-645 (Sm) Human ICAM-1 Detection Kit is designed for detection and quantitation of human ICAM-1 in cell culture supernatant and human serum using a homogeneous AlphaPlex multiplexing assays (no wash steps).
Price Range : 417.00 GBP - 14710.00 GBP

IFN-γ (mouse) LANCE Ultra TR-FRET Detection Kit

The LANCE® Ultra Mouse IFN-γ Detection Kit is designed for detection and quantitation of mouse interferon γ in cell culture media using a homogeneous TR-FRET (no-wash steps, no separation steps) assay.
Price Range : 514.00 GBP - 6830.00 GBP
DELFIA; Eu-N1 Rabbit Anti-Mouse-IgG

DELFIA® Eu-N1 Anti-6xHis

Europium-labeled anti-6X His antibody, for capturing His-tagged proteins in DELFIA® TRF assays. The anti-6xHis antibody is a purified mouse IgG1 monoclonal antibody. It is raised against a polypeptide containing a 6x histidine tag. The antibody has been shown to detect polyhistidine tags localized at the amino- or carboxyl-terminus.
Price Range : 286.00 GBP - 2670.00 GBP
LANCE Detection Kit

ApoA1 (human) LANCE Ultra TR-FRET Detection Kit

The LANCE® Ultra Human ApoA1 Detection Kit is designed for detection and quantitation of human Apolipoprotein A1 (ApoA1) in buffered solution and cell culture media using a homogeneous TR-FRET (no-wash steps, no separation steps) assay.
Price Range : 499.00 GBP - 6660.00 GBP
Assay principle of Alpha Terbium SureFire Ultra assay

Phospho-mTOR (Ser2448) Terbium SureFire Ultra Detection Kit

The Alpha SureFire® Ultra™ Multiplex kits allow the rapid, sensitive, and quantitative detection of two phosphoprotein targets in each well of an assay plate. This kit can be used in combination with any AlphaLISA SureFire Ultra assay to detect phospho-mTOR (Ser2448) in a multiplexed assay.
Price Range : 226.00 GBP - 13610.00 GBP
Receptor-expressing cell lines

ValiScreen Dopamine D3 (human) cell line

Our stable recombinant ValiScreen cell lines express a variety of GPCRs for binding and functional assays.
PerkinElmer

LANCE Ultra Europium-anti-phospho-40S Ribosomal Protein S6 (Ser235/236)

Europium-labeled rabbit monoclonal antibody recognizing human 40S ribosomal protein S6 phosphorylated at both Ser235 and Ser236. Sequence motif recognized: RRL(pS)(pS)LRA
Price Range : 440.00 GBP - 1520.00 GBP
AlphaLISA immunoassay kits

Factor VIII (human) AlphaLISA Detection Kit

The AlphaLISA® Human Factor VIII Detection Kit is designed for detection and quantitation of Human Factor VIII in human serum, plasma, and cell culture supernatants using a homogeneous (no-wash steps, no separation steps) assay.
Price Range : 417.00 GBP - 6500.00 GBP
Receptor-expressing cell lines

Serotonin 5-HT6 AequoScreen; cell line

Our stable recombinant AequoScreen cell lines express a variety of GPCRs which all couple to a calcium response. Upon GPCR stimulation and subsequent calcium binding to the aequorin oxidation of coelenterazine leads to emission of light.
AlphaLISA SureFire Ultra kits

AlphaLISA SureFire Ultra p-Insulin Receptor β (Tyr1150/1151) Assay Kit

The AlphaLISA® SureFire® Ultra™ p-Insulin Receptor β (Tyr1150/1151) assay is a sandwich immunoassay for quantitative detection of phospho-INSR (phosphorylated on Tyr1150/1151) in cellular lysates using Alpha Technology.
Price Range : 316.00 GBP - 18330.00 GBP
Assay principle of Alpha Terbium SureFire Ultra assay

Phospho-AKT (Thr308) Terbium SureFire Ultra Detection Kit

The Alpha SureFire® Ultra™ Multiplex kits allow the rapid, sensitive, and quantitative detection of two phosphoprotein targets in each well of an assay plate. This kit can be used in combination with any AlphaLISA SureFire Ultra assay to detect phospho-AKT (Thr308) in a multiplexed assay.
Price Range : 226.00 GBP - 13610.00 GBP
AlphaLisa Analyte 2

DNA (liquid), AlphaLISA

DNA standard for use in running standard curves in AlphaLISA no-wash immunoassays. This standard is already provided in the AlphaLISA Host Cell Residual DNA kit, but can be ordered separately.
List Price : 160.00 GBP

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