PerkinElmer

Inflammation Research

OF

Inflammation is a natural marker for bodily health, and abnormal inflammatory response is indicated in an increasingly wide net of diseases and disorders, from cardiovascular disease and diabetes to major depression. Detect and quantitate inflammatory biomarkers with our wide range of in vivo, cellular, in situ, and biochemical inflammation research products.

Our products for inflammation research include:

  • LANCE® TR-FRET technology for detection and quantitation of cytokines and other biomarkers
  • AlphaLISA® Immunoassay kits for detection and quantitation of cytokines and other biomarkers
  • DELFIA® (dissociation-enhanced lanthanide fluorescence immunoassay) TRF technology
  • Cellular, tissue, and in vivo imaging systems
  • Near-infrared (NIR) fluorescent and chemiluminescent in vivo imaging agents
  • Target-specific radiolabeled ligands and receptor-transfected cell lines and membranes
  • High content screening

This product portfolio meets the demands of many types of inflammation research:

  • Quick and specific detection of inflammatory biomarkers in human and animal samples, including pro-inflammatory cytokines and chemokines like IL-8, IL-6, IL-2, IFN gamma, and TNF alpha and beta.
  • Monitoring acute and pulmonary inflammation and therapeutic treatment in animal models in real time
  • Phenotypic analysis
  • Targeted studies in various sample types with high sensitivity and specificity

  • Products and Services

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Product Type
  • Accessories (44)
  • Consumables (2)
  • Instruments (8)
  • Reagents (266)
  • Software and Informatics (7)
Assay Target
  • CCL1 (1)
  • CCL18 (1)
  • CCL2 (3)
  • CCL3 (3)
  • CCL4 (1)
  • CCL5 (3)
  • CCL8 (1)
  • CRP (1)
  • CXCL1 (2)
  • CXCL1/GROα (2)
  • CXCL10 (3)
  • CXCL12 (2)
  • CXCL13 (4)
  • CXCL4/PF4 (2)
  • CXCL9 (3)
  • Cyr61 (1)
  • Fibrinogen (2)
  • G-CSF (1)
  • GM-CSF (2)
  • HO-1 (2)
  • HO-2 (2)
  • HVEM (2)
  • IFN-λ2 (4)
  • IFNα (2)
  • IFNγ (10)
  • IL-1RA (4)
  • IL-23 (2)
  • IL-23A (2)
  • IL-31 (2)
  • IL-6 (3)
  • IL10 (2)
  • IL11 (2)
  • IL12 (8)
  • IL13 (3)
  • IL15 (1)
  • IL17A (8)
  • IL17F (4)
  • IL18 (1)
  • IL18BP (2)
  • IL1α (4)
  • IL1β (7)
  • IL2 (4)
  • IL21 (2)
  • IL22 (1)
  • IL23 (1)
  • IL25 (4)
  • IL28B (4)
  • IL31 (1)
  • IL33 (4)
  • IL4 (6)
  • IL5 (4)
  • IL6 (7)
  • IL7 (1)
  • IL8 (3)
  • IP10 (2)
  • MCP2 (1)
  • MIP1α (2)
  • Osteoprotegerin (2)
  • PDGF (2)
  • Periostin (1)
  • SDF1 (2)
  • TNFα (10)
  • TSLP (4)
Target Species
  • Bovine (6)
  • Cynomolgus (4)
  • Human (122)
  • Monkey (2)
  • Mouse (33)
  • Ovine (2)
  • Porcine (4)
  • Rat (1)
Application
  • cAMP (10)
  • Drug Discovery & Development (12)
  • High biotin samples (7)
  • Immunohistochemistry (IHC) (23)
  • In situ hybridization (ISH) (23)
  • In vivo imaging (1)
  • Protein Analysis & Detection (163)
Therapeutic Area
  • Angiogenesis (14)
  • Arthritis (13)
  • Atherosclerosis (9)
  • Cancer (2)
  • Cardiovascular (9)
  • Central Nervous System (3)
  • Gastrointestinal (4)
  • Inflammation (219)
  • Metabolic (4)
  • Oncology/Cancer (13)
  • Pain (8)
  • Vascular disease (5)
Product Brand Name
  • AequoScreen (11)
  • AequoZen (8)
  • AlphaLISA (126)
  • AlphaPlex (4)
  • Ancillary Products (2)
  • cAMPZen (8)
  • Cat B FAST (2)
  • FolateRSense (1)
  • IVIS (6)
  • LANCE Ultra (44)
  • Membrane Target Systems (8)
  • MMPSense (3)
  • Opera Phenix (8)
  • Operetta (29)
  • Operetta CLS (1)
  • ProSense (3)
  • Superhance (1)
  • TSA (12)
  • TSA Plus (12)
  • ValiScreen (10)
  • VivoTrack (2)
  • XenoLight (2)
Detection Method
  • Alpha (131)
  • Chromogenic (6)
  • Fluorescence (27)
  • Time-Resolved Fluorescence (TRF) (24)
  • TR-FRET (24)
  • Transmission (2)
Receptor Type
  • Anaphylatoxin (1)
  • Bradykinin (4)
  • Chemokine (28)
  • Histamine (10)
  • Prostanoid (2)
Assay Validated
  • Binding (23)
  • Calcium Fluorescence (7)
  • Calcium Luminescence (19)
  • cAMP (16)
  • Downstream Phosphorylation (7)
  • GTPγS (8)
  • Inositol Phosphate (2)
Volume Capacity
  • 150 µL (2)
Fluorescent Agent Type
  • Activatable (9)
  • Cell labeling (2)
  • Targeted (1)
  • Vascular (5)
Fluorophore
  • Coumarin (1)
  • Cy3 (8)
  • Cy5 (4)
  • Fluorescein (6)
  • TMR (5)
Assay points(200-50,000)
  • 100 (51)
  • 10000 (28)
  • 500 (116)
  • 5000 (86)
Assay Target Class
  • Cytokine (146)
  • GPCR (45)
  • Protein (20)
Automation Compatible
  • Yes (177)
Experimental Type
  • In vitro (128)
Format
  • Microplates (151)
  • Slides (23)
Host Cell
  • CHO-K1 (42)
  • HEK293 (3)
Imaging Modality
  • Chemilumiluminescence (2)
  • Fluorescence (16)
  • High Content (2)
  • microCT Imaging (1)
  • Optical Imaging (6)
Length
  • 51-100 (6)

"Inflammation" 1-50 of 327 Products and Services

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1000x1000_Opera_Phenix

Opera Phenix High-Content Screening System

The Opera Phenix High Content Screening System is the premier confocal solution for today's most demanding high content applications. Drawing on over a decade of experience with the industry-leading Opera® High Content Screening System, the Opera Phenix is designed for high-throughput, phenotypic screening and assays involving complex disease models, such as live cells, primary cells and microtissues.
IVIS Lumina HT High Throughput Benchtop 2D Optical Imaging System

IVIS Lumina III In Vivo Imaging System

The IVIS® Lumina Series III brings together years of leading optical imaging technologies into one easy to use and exquisitely sensitive bench-top system.
IVIS SpectrumCT 2D/3D Optical/CT In Vivo Imaging System

IVIS SpectrumCT In Vivo Imaging System

The IVIS® SpectumCT preclinical in vivo imaging system expands upon the versatility of the IVIS Spectrum by offering 2D and 3D imaging capabilities but includes integrated low-dose microCT ideal for longitudinal studies. The system provides researchers with greater insights into complex biological systems by enabling simultaneous molecular and anatomical non-invasive imaging in animal models.
1000x1000_Operetta

Operetta CLS High-Content Analysis System

Uncover deep biological understanding in your everyday assays and innovative applications using the Operetta CLS high-content analysis system. Featuring a unique combination of technologies, the system delivers all the speed, sensitivity and resolution you need to reveal fine sub-cellular details. And with our simple, powerful Harmony 4.5 software, Operetta CLS lets you find even subtle phenotypic changes.
IVIS Spectrum In Vivo Imaging System

IVIS Spectrum In Vivo Imaging System

The IVIS® Spectrum in vivo imaging system combines 2D optical and 3D optical tomography in one platform. The system uses leading optical technology for preclinical imaging research and development ideal for non-invasive longitudinal monitoring of disease progression, cell trafficking and gene expression patterns in living animals.
IVIS Lumina HT High Throughput Benchtop 2D Optical Imaging System

IVIS Lumina LT In Vivo Imaging System

The IVIS® Lumina LT Series III pre-clinical in vivo imaging system offers the industries most sensitive benchtop platform at an entry level price.
IVIS Spectrum In Vivo Imaging System

IVIS SpectrumBL High-Throughput In Vivo Optical Imaging System

The IVIS® SpectrumBL is an advanced high-throughput 2D and 3D optical imaging system designed to improve quantitative outcomes of bioluminescent, chemiluminescent and Cerenkov in vivo imaging.
IVIS Lumina XRMS 2D Optical Imaging System with Integrated X-ray

IVIS Lumina XRMS In Vivo Imaging System

Industry leading Fluorescence, Bioluminescence and X-Ray Imaging - All-In-One benchtop instrument! The IVIS® Lumina XRMS (x-ray multi-species optical imaging system) adds to the versatility of the IVIS Lumina XR by offering the flexibility to image large animals up to 500 grams with precise optical and X-Ray overlay.

TNFα (bovine) AlphaLISA Detection Kit

The AlphaLISA immunoassay kit for detection and quantitation of bovine TNFα in serum, plasma, cell culture supernatants, and other sample types allows for fast, reproducible, and sensitive detection without the need for time-consuming wash steps or complicated assay development.
Price Range : 417.00 GBP - 6660.00 GBP
In vivo Fluorescent Agents

AngioSense 680EX Fluorescent Imaging Agent

Near-infrared (NIR) fluorescent agent for in vivo imaging and other applications.
List Price : 514.00 GBP
AlphaPlex Samarium immunoassay kits

AlphaPlex-645 (Sm) Human IL1β Detection Kit

The AlphaPlex™ 645 (Samarium) Human IL1β Detection Kit is designed for the quantitative determination of human insulin together with another analyte (AlphaLISA) in serum, buffered solution or cell culture medium using a homogeneous (no wash steps, no separation steps) assay.
Price Range : 380.00 GBP - 6490.00 GBP
In vivo Fluorescent Agents

AngioSPARK 750 Fluorescent Imaging Agent

Near-infrared (NIR) fluorescent agent for in vivo imaging and other applications.
List Price : 702.00 GBP
AlphaLISA immunoassay kits

IL-1α (bovine) AlphaLISA Detection Kit

The AlphaLISA immunoassay kit for detection and quantitation of bovine IL1α in serum, cell culture supernatants, and other sample types allows for fast, reproducible, and sensitive detection without the need for time-consuming wash steps or complicated assay development.
Price Range : 417.00 GBP - 6660.00 GBP
AlphaLisa Analyte 2

IL-33 (mouse), lyophilized (AlphaLISA)

Mouse IL-33 standard, for use in running standard curves in AlphaLISA assays. This standard is already provided in the AlphaLISA mouse IL-33 Detection Kit, but can also be ordered separately.
List Price : 191.00 GBP
AlphaLISA immunoassay kits

IL-11 (human) AlphaLISA Detection Kit

The AlphaLISA® Human Interleukin 11 (IL-11) Detection Kit is designed for detection and quantitation of IL-11 in serum, buffered solution or cell culture medium in a homogeneous (no-wash steps, no separation steps) assay.
Price Range : 982.00 GBP - 6520.00 GBP
Receptor-expressing cell lines

cAMPZen Frozen cells, Chemokine CXCR2, Human Recombinant, CHO-K1

Our frozen, irradiated cAMPZen cells express a variety of GPCRs for binding and functional assays. No cell culture is required prior to testing.
List Price : 373.00 GBP
In vivo Fluorescent Agents

MMPSense 645 FAST Fluorescent Imaging Agent

Near-infrared (NIR) fluorescent agent for in vivo imaging and other applications. 
List Price : 528.00 GBP
AlphaPlex Terbium immunoassay kits

AlphaPlex-545 Human IL1β Detection Kit

The AlphaPlex™ 545 Human IL1β Detection Kit is designed for the quantitative determination of human IL1β together with another analyte (AlphaLISA) in serum, buffered solution or cell culture medium using a homogeneous assay.
Price Range : 380.00 GBP - 6490.00 GBP

IL-5 (human) LANCE Ultra TR-FRET Detection Kit

The LANCE® Ultra Human IL-5 Detection Kit is designed for detection and quantitation of human interleuukin-5 in cell culture media using a homogeneous TR-FRET (no-wash steps, no separation steps) assay.
Price Range : 514.00 GBP - 6830.00 GBP
AlphaLISA immunoassay kits

IL-4 (mouse) AlphaLISA Detection Kit

The AlphaLISA® immunoassay kit for mouse IL-4 enables the quantitative determination of mouse interleukin-4 in buffered solution and cell culture supernatants using a homogeneous AlphaLISA assay (no wash steps).
Price Range : 388.00 GBP - 9300.00 GBP
AlphaLISA immunoassay kits

IL-17F (human) AlphaLISA Detection Kit

The AlphaLISA® immunoassay kit for IL17F is designed for the quantitative determination of human IL17F in human serum, plasma, cell lysate, and cell culture supernatants using a homogeneous AlphaLISA assay (no wash steps). The assay shows no cross-reactivity with human IL-17A and with mouse IL17F, bovine IL17F, and rat IL17F. Cross-reactivity with other species has not tested.
Price Range : 399.00 GBP - 11980.00 GBP
AlphaLISA immunoassay kits

IL-6 (mouse) AlphaLISA Detection Kit

The AlphaLISA® Mouse Interleukin-6 (IL-6) Detection Kit is designed for detection and quantitation of mouse IL-6 in serum, buffered solution or cell culture medium in a homogeneous (no-wash steps, no separation steps) assay. The kit is a superior alternative to a traditional mouse IL-6 ELISA kit due to its simple and fast protocol, wide dynamic range, and high sensitivity.
Price Range : 982.00 GBP - 6520.00 GBP
AlphaLISA immunoassay kits

IL-6 (monkey) AlphaLISA Detection Kit, 500 Assay Points

The AlphaLISA® immunoassay kit for monkey IL-6 enables the quantitative determination of cynomolgus monkey interleukin-6 in serum, buffered solution, and cell culture supernatants using a homogeneous AlphaLISA assay (no wash steps).
Price Range : 388.00 GBP - 11630.00 GBP
Receptor-expressing cell lines

Chemokine CX3CR1 AequoScreen cell line

Our stable recombinant AequoScreen cell lines express a variety of GPCRs which all couple to a calcium response. Upon GPCR stimulation and subsequent calcium binding to the aequorin oxidation of coelenterazine leads to emission of light.

IL-6 (human) AlphaLISA Biotin-free Detection Kit

The AlphaLISA Human IL-6 Biotin-Free Detection Kit is designed for the quantitative detection of human IL-6 in serum, cell culture medium, and other samples types using a homogeneous (no wash steps, no separation steps) assay. The biotin-free kit uses anti-DIG (anti-Digoxin) Donor beads instead of streptavidin Donor beads, which makes the kit compatible with high-biotin culture media and other sample types that contain high levels biotin (including brain/liver tissue extracts, milk and eggs).
Price Range : 280.00 GBP - 6120.00 GBP

IL-5 (mouse) AlphaLISA Detection Kit

The AlphaLISA® immunoassay kit for mouse IL-5 enables the quantitative determination of mouse interleukin-5 in buffered solution and cell culture supernatants using a homogeneous AlphaLISA assay (no wash steps).
Price Range : 388.00 GBP - 9300.00 GBP
AlphaLISA immunoassay kits

IL-18 (human) AlphaLISA Detection Kit

The AlphaLISA® Human Interleukin 18 (IL-18) Detection Kit is designed for detection and quantitation of human IL-18 in serum, buffered solution or cell culture medium in a homogeneous (no-wash steps, no separation steps) assay.
Price Range : 982.00 GBP - 6520.00 GBP
In vivo Fluorescent Agents

ProSense 750 FAST Fluorescent Imaging Agent

Near-infrared (NIR) fluorescent agent for in vivo imaging and other applications. 
List Price : 513.00 GBP

IL-1β (human) LANCE Ultra TR-FRET Detection Kit

The LANCE® Ultra Human IL-1β Detection Kit is designed for detection and quantitation of human interleuukin-1β in cell culture media using a homogeneous TR-FRET (no-wash steps, no separation steps) assay.
Price Range : 514.00 GBP - 6830.00 GBP

IL-8 (human) LANCE Ultra TR-FRET Detection Kit

The LANCE® Ultra Human IL-8 Detection Kit is designed for detection and quantitation of human interleukin 8 in cell culture media using a homogeneous TR-FRET (no-wash steps, no separation steps) assay.
Price Range : 514.00 GBP - 6830.00 GBP
Receptor-expressing cell lines

AequoZen FroZen Cells, Chemokine CX3CR1, Human Recombinant, CHO-K1

Our frozen, irradiated AequoZen cells express a variety of GPCRs which all couple to a calcium response. Upon GPCR stimulation and subsequent calcium binding to the aequorin oxidation of coelenterazine leads to emission of light. No cell culture is required prior to testing, for these frozen cells.
List Price : 592.00 GBP
AlphaLISA immunoassay kits

IL-22 (human/rat) AlphaLISA Detection kit

AlphaLISA no-wash immunoassay kit for detection and quantitation of human or rat IL-22 in serum, cell culture supernatants, and other samples.
Price Range : 449.00 GBP - 6490.00 GBP
LANCE Detection Kit

IL-11 (human) LANCE Ultra TR-FRET Detection Kit

The LANCE® Ultra Human IL-11 Detection Kit is designed for detection and quantitation of human interleukin-11 in cell culture media using a homogeneous TR-FRET (no-wash steps, no separation steps) assay.
Price Range : 514.00 GBP - 6860.00 GBP
alphaimmunoassay1

IFN-γ (human) AlphaLISA Detection Kit

The AlphaLISA Human IFN-γ Detection Kit is designed for the quantitative determination of human IFN-γ in serum, buffered solution or cell culture medium using a homogeneous (no wash steps, no separation steps) assay.
Price Range : 982.00 GBP - 6520.00 GBP
AlphaPlex Terbium immunoassay kits

AlphaPlex™ 545 IL-6 Detection Kit 

The AlphaPlex™ 545 (Terbium) IL-6 Detection Kit is designed for the quantitative determination of human IL6 together with another analyte (AlphaLISA) in serum, buffered solution or cell culture medium using a homogeneous assay.
Price Range : 392.00 GBP - 6490.00 GBP
AlphaPlex Terbium immunoassay kits

AlphaPlex-545 Human IL17 Detection Kit

The AlphaPlex™ 545 (Terbium) Human IL17 Detection Kit is designed for the quantitative determination of human IL17 together with another analyte (AlphaLISA) in serum, buffered solution or cell culture medium using a homogeneous (no wash steps, no separation steps) assay.
Price Range : 232.00 GBP - 6490.00 GBP
Receptor-expressing cell lines

cAMPZen FroZen Cells, Histamine H2, Human Recombinant, CHO-K1

Our frozen, irradiated cAMPZen cells express a variety of GPCRs for binding and functional assays. No cell culture is required prior to testing.
List Price : 373.00 GBP

TNFα (cynomolgus) AlphaLISA Detection Kit

The AlphaLISA® immunoassay kit for cynomolgus TNFα enables the quantitative determination of cynomolgus tumor necrosis factor alpha in serum, buffered solution, and cell culture supernatants using a homogeneous AlphaLISA assay (no wash steps).
Price Range : 280.00 GBP - 6120.00 GBP
AlphaLisa Analyte 2

PDGF (BB dimer) (human), lyophilized (AlphaLISA)

Human PDGF (BB homodimer) standard, for use in running standard curves in AlphaLISA assays. This standard is already provided in the AlphaLISA human PDGF Detection Kit, but can also be ordered separately.
List Price : 191.00 GBP
AlphaLISA immunoassay kits

IL-15 (human) AlphaLISA Biotin-Free Detection Kit

The AlphaLISA® Human IL-15 Biotin-Free Detection Kit is designed for the quantitative detection of human Interleukin 15 in serum, cell culture medium, and other samples types using a homogeneous (no wash steps, no separation steps) assay. The biotin-free kit is compatible with high-biotin culture media and other sample types that contain high levels biotin.
Price Range : 288.00 GBP - 6300.00 GBP
AlphaLisa Analyte 2

HVEM (human), lyophilized (AlphaLISA)

Human HVEM standard, for use in running standard curves in AlphaLISA assays. This standard is already provided in the AlphaLISA human HVEM Detection Kit, but can also be ordered separately.
List Price : 261.00 GBP
AlphaLISA immunoassay kits

Monocyte Chemoattractant Protein-1 (human) AlphaLISA Detection Kit

The AlphaLISA® Human Monocyte Chemoattractant Protein-1 (CCL2 / MCP1) Detection Kit is designed for detection and quantitation of human CCL2/MCP1 in serum, buffered solution or cell culture medium in a homogeneous (no-wash steps, no separation steps) assay.
Price Range : 982.00 GBP - 6520.00 GBP
TSA Biotin System

TSA Biotin System

TSA® biotin detection kit, for amplification of signal in immunohistochemistry (IHC), immunofluorescence (IF) or in situ hybridization protocols. This kit amplifies by depositing extra biotin in the localized area of the probe or antibody.
Price Range : 253.00 GBP - 845.00 GBP
AlphaLISA immunoassay kits

CXCL12/SDF-1 (human) AlphaLISA Detection Kit

The AlphaLISA® immunoassay kit for human CXCL12 (SDF-1) enables the quantitative determination of human CXCL12 in serum, buffered solution, and cell culture supernatants using a homogeneous AlphaLISA assay (no wash steps).
Price Range : 280.00 GBP - 6120.00 GBP
LANCE Detection Kit

IL17F (human) LANCE Ultra TR-FRET Detection Kit

The LANCE® Ultra Human IL-17F Detection Kit is designed for detection and quantitation of human interleukin 17 in buffered solution and cell culture media using a homogeneous TR-FRET (no-wash steps, no separation steps) assay.
Price Range : 514.00 GBP - 6860.00 GBP
PerkinElmer

Membrane Target Systems: Chemoattractant C5a (human varient) membrane preparation, in CHO-K1 cells. 400 Units.

Cell membranes prepared from CHO-K1 cells stably-transfected with human chemoattractant C5a (human varient) receptor, 400 units.
List Price : 569.00 GBP
Protein

Osteoprotegerin (human), lyophilized (AlphaLISA)

Human osteoprotegerin standard, for use in running standard curves in AlphaLISA assays.
List Price : 197.00 GBP
AlphaLISA immunoassay kits

IL-17A (mouse/rat) AlphaLISA Biotin-free Detection Kit

The AlphaLISA Mouse/Rat IL-17A Biotin-Free Detection Kit is designed for the quantitative detection of mouse or rat IL-17 (IL-17A) in serum, cell culture medium, and other samples types using a homogeneous (no wash steps, no separation steps) assay. The biotin-free kit uses anti-DIG (anti-Digoxin) Donor beads instead of streptavidin Donor beads, which makes the kit compatible with high-biotin culture media and other sample types that contain high levels biotin (including brain/liver tissue extracts, milk and eggs).
Price Range : 297.00 GBP - 6490.00 GBP
AlphaLISA immunoassay kits

HVEM (human) AlphaLISA Detection Kit

The AlphaLISA® immunoassay kit for human herpesvirus entry mediator (HVEM) enables the quantitative determination of human HVEM (also known as TNFRSF14, CD270) in buffered solution and cell culture supernatants using a homogeneous AlphaLISA assay (no wash steps).
Price Range : 485.00 GBP - 9300.00 GBP
Receptor-expressing cell lines

ValiScreen Chemokine CCR7 (human) cell line

Our stable recombinant ValiScreen cell lines express a variety of GPCRs for binding and functional assays.

"Inflammation" 1-50 of 327 Products and Services

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