PerkinElmer

Ligands

OF

Eliminate the need for antibodies and reduce assay time with direct detection using our radiolabeled ligands, which provide for sensitive and quantitative measurement of binding.

  • High specific activity — The majority of our 125I-labeled ligands are offered at maximum specific activity. This means virtually every molecule of ligand provided in the stock vial is radiolabeled. For tritiated ligands (3H ligands), pick a ligand with specific activity above 20 Ci/mmol – all of our tritiated ligands meets or exceeds these requirements.
  • High purity — We offer highly-pure radioligands for the highest specific signal with low background in binding assays.
  • High selectivity — Our broad portfolio of agonists and antagonists offers many options for choosing the most selective compound for your receptor.
  • Validated for receptor binding — all of our radioligand products are tested for receptor binding during development. Additionally, many of our radioligands are used to QC our GPCR and receptor cell lines and cell membrane products.

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"Ligands" 1-50 of 116 Products and Services

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Adenosine 5 Triphosphate 250 µCi

Rosiglitazone, DL- [3H]-

Tritiated DL-Rosiglitazone (Avandia). Rosiglitazone acts as a selective agonist at peroxisome proliferator-activated receptors (PPARs).
List Price : 1460.00 GBP
Adenosine 5 Triphosphate 250 µCi

CGP 39653, [Propyl-2,3,3H]

CGP 39653, tritiated at the propyl-2,3 position. CGP 39653 acts as an N-methyl-D-aspartate (NMDA) antagonist.
Price Range : 562.00 GBP - 4800.00 GBP
Adenosine 5 Triphosphate 250 µCi

Amino-3-Hydroxy-5-Methylisoxazole-4-Propionic Acid (AMPA), DL-α-[5-Methyl-3H]

DL-α-Amino-3-Hydroxy-5-Methylisoxazole-4-Propionic Acid (AMPA), tritiated at the 5-methyl position. AMPA acts as an agonist at the AMPA receptor.
Price Range : 498.00 GBP - 3680.00 GBP

GR113808,[N-methyl-3H]-

GR113808, tritiated on the N-methyl group. GR113808 acts as a selective antagonist at the 5-HT4 receptor.
List Price : 3580.00 GBP
Adenosine 5 Triphosphate 250 µCi

WIN 35428, [N-Methyl-3H]

WIN 35428 [(–)-2-β-Carbomethoxy-3-β-(4-fluorophenyl)tropane], tritiated on the N-methyl group. WIN 35428 acts as an antagonist at dopamine transporters (DATs).
Price Range : 620.00 GBP - 4440.00 GBP
Adenosine 5 Triphosphate 250 µCi

Ethylcarboxamidoadenosine, 5`-N-[Adenine-2,8-3H]-, 250µCi (9.25MBq)

5'-N-Ethylcarboxamidoadenosine (NECA), tritiated at the adenine-2,8 position. 5'-N-Ethylcarboxamidoadenosine is an adenosine analog that acts as an agonist at adenosine receptors A1, A2A, and A3.
List Price : 1390.00 GBP
Adenosine 5 Triphosphate 250 µCi

Astemizole, [O-Methyl-3H]

Astemizole (Hismanal) tritiated at the O-methyl group. Atemizole is an antagonist of the histamine H1-receptor and has been shown to block hERG potassium channels.
Price Range : 616.00 GBP - 6970.00 GBP
Adenosine 5 Triphosphate 250 µCi

Taurine, [2,2,3H]

Taurine, tritiated at the 2,2 position. Taurine acts as an agonist at glycine receptors.
List Price : 1130.00 GBP
Adenosine 5 Triphosphate 250 µCi

Prazosin, [7-Methoxy-3H]

Prazosin, tritiated at the 7-methoxy position. Prazosin acts as an inverse agonist at the α1-adrenergic receptor.
Price Range : 614.00 GBP - 4850.00 GBP
Adenosine 5 Triphosphate 250 µCi

DAMGO, [Tyrosyl-3,5-3H(N)]

DAMGO, tritiated at the tyrosyl 3,5 poisition. DAMGO is a synthetic opioid analog with high specificity for the μ-opioid receptor.
Price Range : 1510.00 GBP - 3910.00 GBP
Adenosine 5 Triphosphate 250 µCi

Acetylcholine Iodide, [acetyl-3H], 1mCi (37MBq)

Acetylcholine (Ach) radioligand tritiated on the acetyl group. Acetylcholine is a neurotransmitter and the endogeous ligand that binds to and activates muscarinic and nicotinic acetylcholine receptors.
List Price : 669.00 GBP
Adenosine 5 Triphosphate 250 µCi

Bradykinin, [2,3-Prolyl-3,4-3H(N)]

Bradykinin, tritiated at the 2,3-prolyl-3,4 position. Bradykinin is the endogenous ligand that activates bradykinin B1 and B2 receptors.
Price Range : 1550.00 GBP - 3530.00 GBP
Adenosine 5 Triphosphate 250 µCi

Ketanserin Hydrochloride (R41 468), [Ethylene-3H]

Ketanserin hydrochloride (Sufrexal; R41468), tritiated on the ethylene group. Ketanserin is a high-affinity non-selective antagonist of 5-HT2 receptors.
Price Range : 540.00 GBP - 1800.00 GBP
Adenosine 5 Triphosphate 250 µCi

U-69,593, [Phenyl-3,4-3H]

U-69,593, tritiated at the phenyl-3,4 position. U-69,593 is a selective κ1-opioid receptor agonist.
Price Range : 608.00 GBP - 1980.00 GBP
Adenosine 5 Triphosphate 250 µCi

Methylspiperone, [N-Methyl-3H]-, 250µCi (9.25MBq)

Methylspiperone radioligand tritiated at the N-Methyl position. Methylspiperone is an antagonist at the 5-HT2A receptor and a selective dopamine D2 antagonist.
List Price : 2070.00 GBP
Adenosine 5 Triphosphate 250 µCi

NAAG, [Glutamate-3,4-3H]

NAAG radioligand tritiated at the 3,4 position. NAAG is a peptide neurotransmitter that activates the metabotropic glutamate receptor type 3.
List Price : 1140.00 GBP
Adenosine 5 Triphosphate 250 µCi

MDL105,519, [3H]

Tritiated MDL 105,519. MDL 105,519 acts as a potent and selective antagonist at N-methyl-D-aspartate (NMDA) receptors.
List Price : 2360.00 GBP
Adenosine 5 Triphosphate 250 µCi

Paroxetine, [Phenyl-6'-3H]

Paroxetine (Paxil), tritiated at the phenyl-6' position. Paroxetine is a selective serotonin reuptake inhibitor (SSRI). This product has a scheduled lot release for the first Monday in May and November.
Price Range : 546.00 GBP - 3090.00 GBP
Adenosine 5 Triphosphate 250 µCi

5-Hydroxytryptamine Creatinine Sulfate, [1,2-3H(N)]

5-Hydroxytryptamine Creatinine Sulfate (Serotonin, 5-HT), tritiated at the 1,2 position. 5-Hydroxytryptamine is a neurotransmitter and is the endogenous ligand for serotonin receptors.
Price Range : 656.00 GBP - 1770.00 GBP
Adenosine 5 Triphosphate 250 µCi

Escitalopram, [N-methyl-3H]-

Escitalopram (Cipralex), tritiated at the N-methyl position. Escitalopram is a selective serotonin reuptake inhibitor (SSRI) with high selectivity for the serotonin transporter (SERT) compared to the norepinephrine transporter (NET).
List Price : 3930.00 GBP
Adenosine 5 Triphosphate 250 µCi

Thyrotropin Releasing Hormone, [L-histidyl-4-3H(N), L-propyl-3,4-3H(N)]

Thyrotropin-releasing hormone (TRH), tritiated on the histidyl and propyl groups. TRH binds and activates thyrotropin-releasing hormone receptors (TRH-Rs).
Price Range : 1440.00 GBP - 5260.00 GBP
Adenosine 5 Triphosphate 250 µCi

RX 821002, [6,7-3H(N)]-

RX 821002, tritiated at the 6,7 position. RX 821002 acts as an antagonist at α2-adrenoceptors.
List Price : 2050.00 GBP
Diclofenac sodium- Phenylacetic acid C14

COUMARIN, 7-ETHOXY, [3- 14C]-

50 µCi quantities of 7-ETHOXY-[3-14C]-Coumarin are available for your research.
List Price : 1710.00 GBP
Adenosine 5 Triphosphate 250 µCi

Nisoxetine Hydrochloride, [N-Methyl-3H]-, 250µCi (9.25MBq)

Nisoxetine hydrochloride, tritiated on the N-methyl group. Nisoxetine is a potent and selective inhibitor of the norepinephrine transporter.
List Price : 1980.00 GBP
Adenosine 5 Triphosphate 250 µCi

Raclopride, [Methoxy-3H]

Raclopride, [Methoxy-3H]- will have fresh lot dates on the second Monday in March and September.
Price Range : 491.00 GBP - 3920.00 GBP
Diclofenac sodium- Phenylacetic acid C14

Ascorbic Acid, L-[1-14C]-,>97%, 50µCi (1.85MBq)

L-Ascorbic acid (reduced form of vitamin C; ascorbate), labeled with C-14 at the 1- position. L-ascorbic acid is a vitamin that binds and is transported through sodium-dependent vitamin C transporters (SVCT1 and SCVT2).
List Price : 802.00 GBP
Adenosine 5 Triphosphate 250 µCi

Norepinephrine, Levo-[7-3H]

Levo-Norepinephrine, tritiated at the 7 position. Norepinephrine binds and activates adrenergic receptors, and is cleared by the norepinehprine transporter (NET). This product has a scheduled lot release for the third Monday in July.
Price Range : 1050.00 GBP - 8750.00 GBP
Adenosine 5 Triphosphate 250 µCi

(-)-CGP-12177, [5,7-3H]

(-)-CGP-12177 radioligand tritiated at the 5,7 position. CGP-12177 acts as an antagonist at the β1- and β2-adrenoceptors and a partial agonist at β3-adrenoceptors.
Price Range : 450.00 GBP - 1120.00 GBP
Adenosine 5 Triphosphate 250 µCi

Dihydroalprenolol Hydrochloride, Levo-[Ring, Propyl-3H(N)]

Dihydroalprenolol hydrochloride, tritiated on the ring propyl group. Dihydroalprenolol (DHA) is an alprenolol derivative that binds to beta-adrenergic receptors and acts as a beta-adrenergic blocker.
Price Range : 862.00 GBP - 1960.00 GBP
Adenosine 5 Triphosphate 250 µCi

SR141716A, [3H]

Tritiated SR141716A (rimonabant; Acomplia; Zimulti). SR141716A acts as an inverse agonist at the cannabinoid CB1 receptor.
List Price : 2180.00 GBP
Adenosine 5 Triphosphate 250 µCi

Diprenorphine [15,16-3H]

Diprenorphine (Revivon; M5050; diprenorfin), tritiated at the 15,16- position. Diprenorphine acts as a non-selective antagonist at opioid receptors.
Price Range : 524.00 GBP - 1490.00 GBP
Adenosine 5 Triphosphate 250 µCi

AF-DX 384, [2,3-Dipropylamino-3H]-, 250µCi (9.25MBq)

AFDX-384 (BIBN-161) radioligand tritiated at the 2,3-dipropylamino position. AFDX-384 acts as a selective antagonist of muscarinic acetylcholine receptors, with selectivity for the M2 and M4 subtypes.
List Price : 1710.00 GBP
Adenosine 5 Triphosphate 250 µCi

SB-269970, [3H]

Tritiated SB-269970. SB-269970 is believed to act as a selective serotonin 5-HT7 antagonist, or possibly an inverse agonist.
List Price : 3390.00 GBP
Adenosine 5 Triphosphate 250 µCi

Ryanodine, [9,21-3H(N)]-, 250µCi (9.25MBq)

Ryanodine, tritiated at the 9,21 position. Ryanodine is a natural ligand for the ryanodinen receptor.
List Price : 2020.00 GBP
Adenosine 5 Triphosphate 250 µCi

Glibenclamide, Glyburide, [Cyclohexyl-2,3-3H(N)]-, 250µCi (9.25MBq)

Glibenclamide (glyburide) tritiated at the cyclohexyl-2,3 position. Glibenclamide is an antidiabetic drug that binds and inhibits the ATP-sensitive potassium channel.
List Price : 2540.00 GBP
Adenosine 5 Triphosphate 250 µCi

Diltiazem, cis-(+)-[N-Methyl-3H]

cis-(+)-Diltiazem, tritiated at the N-methyl position. Diltiazem is a non-DHP calcium channel blocker.
Price Range : 1440.00 GBP - 3670.00 GBP
Adenosine 5 Triphosphate 250 µCi

Scopolamine Methyl Chloride, [N-methyl-3H]

Scopolamine methyl chloride, tritiated on the N-methyl group. Scopolamine acts as an antagonist at muscarinic acetylcholine receptors.
Price Range : 1330.00 GBP - 3050.00 GBP
Adenosine 5 Triphosphate 250 µCi

Methylhistamine Dihydrochloride, N-α-[methyl-3H]-, 250µCi (9.25MBq)

(R)-α-methylhistamine dihydrochloride, tritiated on the methyl group. α-Methylhistamine is a histamine agonist selective for the histamine H3 receptor.
List Price : 1050.00 GBP
Adenosine 5 Triphosphate 250 µCi

Chloramphenicol, [Ring-3,5-3H]

Chloramphenicol, tritiated at the ring-3,5 position. Chloramphenicol is a broad spectrum antibiotic that binds to a receptor site on the 50S subunit of the bacterial ribosome, inhibiting peptidyl transferase.
Price Range : 1660.00 GBP - 4130.00 GBP
Diclofenac sodium- Phenylacetic acid C14

DICLOFENAC SODIUM[PHENYLACETIC ACID RING- U-14C]

Diclofenac sodium, labeled with C-14 on the phenylacetic acid ring. Diclofenac is a nonsteroidal anti-inflammatory drug (NSAID) that acts as an antagonist at peroxisome prolifeator-activated receptor gamma (PPAR-γ or PPARG).
List Price : 2060.00 GBP
Diclofenac sodium- Phenylacetic acid C14

Hydroxytryptamine Binoxalate (Serotonin Binoxalate), 5-[1-14C]

5-Hydroxytryptamine Binoxalate (Serotonin Binoxalate), labeled with C-14 at the 1-position. 5-Hydroxytryptamine is a neurotransmitter and is the endogenous ligand for serotonin receptors. NEC855 replaces product NEC225, which was labeled at the 2-position.
Price Range : 671.00 GBP - 3260.00 GBP
Adenosine 5 Triphosphate 250 µCi

Norepinephrine Hydrochloride, DL-[7-3H(N)]-, 250µCi (9.25MBq)

DL-Norepinephrine hydrochloride, tritiated at the 7 position. Norepinephrine binds and activates adrenergic receptors, and is cleared by the norepinehprine transporter (NET).
List Price : 1010.00 GBP
Adenosine 5 Triphosphate 250 µCi

Pirenzepine, [N-Methyl-3H]

Pirenzepine, tritiated on the N-methyl group. Pirenzepine acts as a selective antagonist of the muscarinic M1 acetylcholine receptor.
Price Range : 1710.00 GBP - 4320.00 GBP
Adenosine 5 Triphosphate 250 µCi

Enkephalin (2-D-Alanine-5-D-Leucine), [Tyrosyl-3,5-3H(N)]-, 250µCi (9.25MBq)

DADLE, tritiated on the tyrosyl group. Peptide sequence: Tyr-D-Ala-Gly-L-Phe-D-Leu. DADLE is a synthetic enkephalin analog considered selective for the delta opioid receptor, but has been shown to bind the mu opioid receptor as well.
List Price : 1610.00 GBP
Adenosine 5 Triphosphate 250 µCi

α-BUNGAROTOXIN,N-[3H]

α-Bungarotoxin (α-BTX) radioligand tritiated on the propionyl group. α-BTX acts as an antagonist at nicotinic acetylcholine receptors. α-Bungarotoxin,N-[3H] is part of a scheduled release program and is available on the second Monday in August.
List Price : 5260.00 GBP
Adenosine 5 Triphosphate 250 µCi

TCP, [Piperdyl-3,4-3H(N)]

Tenocyclidine (TCP), tritiated at the piperdyl-3,4 position. TCP acts as an antagonist at N-methyl-D-aspartate receptor (NMDA receptors).
Price Range : 570.00 GBP - 2360.00 GBP
Adenosine 5 Triphosphate 250 µCi

Oxotremorine-M Acetate, [Methyl-3H]-,>97%, 250µCi (9.25MBq)

Oxotremorine-M acetate, tritiated on the methyl group. Oxotremorine-M acts as a selective agonist at muscarinic acetylcholine receptors.
List Price : 2010.00 GBP
Adenosine 5 Triphosphate 250 µCi

Histamine Dihydrochloride, [Ring, Methylenes-3H(N)]

Histamine dihydrochloride, tritiated on the ring and methylene groups. Histamine is an endogenous agonist of histamine receptors.
Price Range : 950.00 GBP - 2630.00 GBP

Butyl Bicyclophosphorothionate, Tertiary-[35S]

Tertiary-Butylbicyclophosphorothionate (TBPS), radiolabeled with S-35. TBPS is a GABAA receptor antagonist.
Price Range : 1760.00 GBP - 3110.00 GBP
Adenosine 5 Triphosphate 250 µCi

Norepinephrine, Levo-[ring-2,5,6-3H]

Levo-Norepinephrine, tritiated on the ring group. Norepinephrine binds and activates adrenergic receptors, and is cleared by the norepinehprine transporter (NET).
Price Range : 1170.00 GBP - 7430.00 GBP

"Ligands" 1-50 of 116 Products and Services

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