PerkinElmer

Ligands

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Eliminate the need for antibodies and reduce assay time with direct detection using our radiolabeled ligands, which provide for sensitive and quantitative measurement of binding.

  • High specific activity — The majority of our 125I-labeled ligands are offered at maximum specific activity. This means virtually every molecule of ligand provided in the stock vial is radiolabeled. For tritiated ligands (3H ligands), pick a ligand with specific activity above 20 Ci/mmol – all of our tritiated ligands meets or exceeds these requirements.
  • High purity — We offer highly-pure radioligands for the highest specific signal with low background in binding assays.
  • High selectivity — Our broad portfolio of agonists and antagonists offers many options for choosing the most selective compound for your receptor.
  • Validated for receptor binding — all of our radioligand products are tested for receptor binding during development. Additionally, many of our radioligands are used to QC our GPCR and receptor cell lines and cell membrane products.

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Radioisotope
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"Ligands" 1-50 of 119 Products and Services

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Adenosine 5 Triphosphate 250 µCi

8-Hydroxy-DPAT, [Propyl-2,3-ring-1,2,3-3H]-

8-OH-DPAT radioligand tritiated at the 1,2,3 position on the propyl-2,3-ring. 8-OH-DPAT is a serotonin receptor agonist specific for the 5-HT1A and 5-HT7 receptors.
Price Range : 960.00 GBP - 2440.00 GBP
Adenosine 5 Triphosphate 250 µCi

Chloramphenicol, [Ring-3,5-3H]

Chloramphenicol, tritiated at the ring-3,5 position. Chloramphenicol is a broad spectrum antibiotic that binds to a receptor site on the 50S subunit of the bacterial ribosome, inhibiting peptidyl transferase.
Price Range : 1510.00 GBP - 3310.00 GBP
Adenosine 5 Triphosphate 250 µCi

NAAG, [Glutamate-3,4-3H]

NAAG radioligand tritiated at the 3,4 position. NAAG is a peptide neurotransmitter that activates the metabotropic glutamate receptor type 3.
Price Range : 1040.00 GBP - 2260.00 GBP
Adenosine 5 Triphosphate 250 µCi

Colchicine, [ring C, Methoxy-3H]-, 250µCi (9.25MBq)

Colchicine, tritiated at the ring C methoxy- position. Colchicine binds tubulin to prevent microtubule polymerization, and is used to treat gout.
List Price : 1400.00 GBP
Adenosine 5 Triphosphate 250 µCi

Mazindol, [4`-3H]-, 250µCi (9.25MBq)

Mazindol, tritiated at the 4' position. Mazindol has been shown to block dopamine (DAT), serotonin (SERT), and norepinephrine (NET) transporters.
List Price : 1950.00 GBP
Diclofenac sodium- Phenylacetic acid C14

DICLOFENAC SODIUM[PHENYLACETIC ACID RING- U-14C]

Diclofenac sodium, labeled with C-14 on the phenylacetic acid ring. Diclofenac is a nonsteroidal anti-inflammatory drug (NSAID) that acts as an antagonist at peroxisome prolifeator-activated receptor gamma (PPAR-γ or PPARG).
List Price : 1870.00 GBP
Adenosine 5 Triphosphate 250 µCi

Dihydroalprenolol Hydrochloride, Levo-[Ring, Propyl-3H(N)]

Dihydroalprenolol hydrochloride, tritiated on the ring propyl group. Dihydroalprenolol (DHA) is an alprenolol derivative that binds to beta-adrenergic receptors and acts as a beta-adrenergic blocker.
Price Range : 784.00 GBP - 1780.00 GBP
Adenosine 5 Triphosphate 250 µCi

CP 55940, [Side Chain-2,3,4-3H(N)]

CP 55,940, tritiated on the side chain-2,3-4 position. CP 55,940 is a synthetic cannabinoid that acts as a full agonist at both cannabinoid CB1 and CB2 receptors, and can also upregulate serotonin 5-HT2A receptors.
Price Range : 535.00 GBP - 3930.00 GBP
Adenosine 5 Triphosphate 250 µCi

Dihydroxyphenylethylamine, 3,4-[7-3H]

Dihydroxyphenylethylamine (dopamine, DA), tritiated at the 7 position. Dihydroxyphenylethylamine is a neurotransmitter and is the primary endogenous ligand for dopamine receptors. This product has a scheduled lot release for the second Monday in April and October.
Price Range : 641.00 GBP - 1800.00 GBP

Ro 15-1788, [N-Methyl-3H]

Ro 15-1788 (flumazenil), tritiated on the N-methyl group. Ro 15-1788 acts as a selective benzodiazepine antagonist.
Price Range : 519.00 GBP - 3890.00 GBP
Adenosine 5 Triphosphate 250 µCi

Norepinephrine Hydrochloride, DL-[7-3H(N)]-, 250µCi (9.25MBq)

DL-Norepinephrine hydrochloride, tritiated at the 7 position. Norepinephrine binds and activates adrenergic receptors, and is cleared by the norepinehprine transporter (NET).
List Price : 806.00 GBP
Adenosine 5 Triphosphate 250 µCi

Raclopride, [Methoxy-3H]

Raclopride, [Methoxy-3H]- will have fresh lot dates on the second Monday in March and September.
Price Range : 446.00 GBP - 3570.00 GBP
Adenosine 5 Triphosphate 250 µCi

5-CT, [3H]

5-carboxyamidotryptamine (5-CT) labeled with tritium. 5-CT is a tryptamine derivative closely related to the neurotransmitter serotonin. 5-CT acts as a non-selective, high-affinity full agonist at the 5-HT1A, 5-HT1B, 5-HT1D, 5-HT5A, and 5-HT7 serotonin receptors. It also binds the 5-HT2, 5-HT3, 5-HT6 serotonin receptors with lower affinity.
List Price : 1010.00 GBP
Adenosine 5 Triphosphate 250 µCi

Bradykinin, [2,3-Prolyl-3,4-3H(N)]

Bradykinin, tritiated at the 2,3-prolyl-3,4 position. Bradykinin is the endogenous ligand that activates bradykinin B1 and B2 receptors.
Price Range : 1410.00 GBP - 3210.00 GBP
Adenosine 5 Triphosphate 250 µCi

Scopolamine Methyl Chloride, [N-methyl-3H]

Scopolamine methyl chloride, tritiated on the N-methyl group. Scopolamine acts as an antagonist at muscarinic acetylcholine receptors.
Price Range : 1210.00 GBP - 2770.00 GBP
Adenosine 5 Triphosphate 250 µCi

Deltorphin II (2-D-Ala), [Tyrosyl-3,5-3H]

Deltorphin II, tritiated at the tyrosyl-3,5 position. Deltorphin II is a selective δ opioid receptor (DOPR) agonist.
Price Range : 730.00 GBP - 3090.00 GBP
Adenosine 5 Triphosphate 250 µCi

Taurine, [2,2,3H]

Taurine, tritiated at the 2,2 position. Taurine acts as an agonist at glycine receptors.
Price Range : 945.00 GBP - 3040.00 GBP
Adenosine 5 Triphosphate 250 µCi

PK 11195, [N-Methyl-3H]

PK-11195, tritiated on the N-methyl group. PK-11195 binds selectively to the peripheral benzodiazepine receptor (PBR).
Price Range : 485.00 GBP - 3580.00 GBP
Adenosine 5 Triphosphate 250 µCi

Amino-3-Hydroxy-5-Methylisoxazole-4-Propionic Acid (AMPA), DL-α-[5-Methyl-3H]

DL-α-Amino-3-Hydroxy-5-Methylisoxazole-4-Propionic Acid (AMPA), tritiated at the 5-methyl position. AMPA acts as an agonist at the AMPA receptor.
Price Range : 453.00 GBP - 3350.00 GBP
Adenosine 5 Triphosphate 250 µCi

NALOXONE, [N-ALLYL-2,3-3H]-

Naloxone radioligand tritiated at the 2,3 position. Naloxone acts as a non-selective, competitive opioid receptor antagonist.
List Price : 1310.00 GBP
Adenosine 5 Triphosphate 250 µCi

Vinblastine Sulphate, [G-3H]

Vinblastine sulphate, tritiated. Vinblastine binds to tubulin and inhibits microtubule formation.
Price Range : 1220.00 GBP - 4570.00 GBP
Adenosine 5 Triphosphate 250 µCi

Flunitrazepam, [Methyl-3H]

Flunitrazepam (Rohypnol), tritiated on the methyl group. Flunitrazepam is a benzodiazepine and acts as an agonist at GABAA (γ-aminobutyric acid) receptors.
Price Range : 423.00 GBP - 4240.00 GBP
Adenosine 5 Triphosphate 250 µCi

TCP, [Piperdyl-3,4-3H(N)]

Tenocyclidine (TCP), tritiated at the piperdyl-3,4 position. TCP acts as an antagonist at N-methyl-D-aspartate receptor (NMDA receptors).
Price Range : 518.00 GBP - 1890.00 GBP
Adenosine 5 Triphosphate 250 µCi

Kainic acid, [Isopropenyl-3H]

Kainic acid, tritiated on the isoproprenyl group. Kainic acid acts as an agonist at kainate glutamate receptors.
Price Range : 454.00 GBP - 4200.00 GBP
Adenosine 5 Triphosphate 250 µCi

(+/-) Epibatidine, [5,6-Bicycloheptyl-3H]

(+/-)-Epibatidine radioligand tritiated at the 5,6-biocycloheptyl position. Epibatidine has analgesic activities, has been shown to function as an agonist at nicotinic acetylcholine receptors, and has been shown to bind muscarinic and serotonin 5-HT3 receptors.
Price Range : 1380.00 GBP - 3300.00 GBP
Adenosine 5 Triphosphate 250 µCi

5-Hydroxy tryptamine, [3H]

5-hydroxytryptamine (5-HT, or serotonin) labeled with tritium. It is a naturally occurring neurotransmitter which is tied to positive mood, certain involuntary muscle control, and countless other functions.
Price Range : 492.00 GBP - 1800.00 GBP
Adenosine 5 Triphosphate 250 µCi

CGP 39653, [Propyl-2,3,3H]

CGP 39653, tritiated at the propyl-2,3 position. CGP 39653 acts as an N-methyl-D-aspartate (NMDA) antagonist.
Price Range : 511.00 GBP - 4370.00 GBP
Adenosine 5 Triphosphate 250 µCi

Ketanserin Hydrochloride (R41 468), [Ethylene-3H]

Ketanserin hydrochloride (Sufrexal; R41468), tritiated on the ethylene group. Ketanserin is a high-affinity non-selective antagonist of 5-HT2 receptors.
Price Range : 491.00 GBP - 4400.00 GBP
Adenosine 5 Triphosphate 250 µCi

Prazosin, [7-Methoxy-3H]

Prazosin, tritiated at the 7-methoxy position. Prazosin acts as an inverse agonist at the α1-adrenergic receptor.
Price Range : 558.00 GBP - 4410.00 GBP
Adenosine 5 Triphosphate 250 µCi

Verapamil Hydrochloride, [N-Methyl-3H]

Verapamil hydrochloride, tritiated on the N-methyl group. Verapamil acts as a calcium channel blocker (CCB).
Price Range : 544.00 GBP - 2060.00 GBP
Adenosine 5 Triphosphate 250 µCi

Pirenzepine, [N-Methyl-3H]

Pirenzepine, tritiated on the N-methyl group. Pirenzepine acts as a selective antagonist of the muscarinic M1 acetylcholine receptor.
Price Range : 1550.00 GBP - 3930.00 GBP
Adenosine 5 Triphosphate 250 µCi

Oxotremorine-M Acetate, [Methyl-3H]-,>97%, 250µCi (9.25MBq)

Oxotremorine-M acetate, tritiated on the methyl group. Oxotremorine-M acts as a selective agonist at muscarinic acetylcholine receptors.
List Price : 1830.00 GBP
Adenosine 5 Triphosphate 250 µCi

Enkephalin (2-D-Alanine-5-D-Leucine), [Tyrosyl-3,5-3H(N)]-, 250µCi (9.25MBq)

DADLE, tritiated on the tyrosyl group. Peptide sequence: Tyr-D-Ala-Gly-L-Phe-D-Leu. DADLE is a synthetic enkephalin analog considered selective for the delta opioid receptor, but has been shown to bind the mu opioid receptor as well.
List Price : 1350.00 GBP
Adenosine 5 Triphosphate 250 µCi

α-BUNGAROTOXIN,N-[3H]

α-Bungarotoxin (α-BTX) radioligand tritiated on the propionyl group. α-BTX acts as an antagonist at nicotinic acetylcholine receptors. α-Bungarotoxin,N-[3H] is part of a scheduled release program and is available on the second Monday in August.
List Price : 3760.00 GBP
Adenosine 5 Triphosphate 250 µCi

Diltiazem, cis-(+)-[N-Methyl-3H]

cis-(+)-Diltiazem, tritiated at the N-methyl position. Diltiazem is a non-DHP calcium channel blocker.
Price Range : 1310.00 GBP - 2940.00 GBP
Adenosine 5 Triphosphate 250 µCi

Thyrotropin Releasing Hormone, [L-histidyl-4-3H(N), L-propyl-3,4-3H(N)]

Thyrotropin-releasing hormone (TRH), tritiated on the histidyl and propyl groups. TRH binds and activates thyrotropin-releasing hormone receptors (TRH-Rs).
Price Range : 1310.00 GBP - 4780.00 GBP
Adenosine 5 Triphosphate 250 µCi

Norepinephrine, Levo-[7-3H]

Levo-Norepinephrine, tritiated at the 7 position. Norepinephrine binds and activates adrenergic receptors, and is cleared by the norepinehprine transporter (NET). This product has a scheduled lot release for the third Monday in July.
Price Range : 956.00 GBP - 7290.00 GBP
Adenosine 5 Triphosphate 250 µCi

Quinuclidinyl Benzilate, L-[Benzilic-4,4`-3H]-, 250µCi (9.25MBq)

L-quinuclidinyl benzilate (QNB), tritiated at the benzilic-4,4' position. L-quinuclidinyl benzilate acts as an antagonist at muscarinic acetylcholine receptors.
List Price : 1120.00 GBP
Adenosine 5 Triphosphate 250 µCi

Methylhistamine Dihydrochloride, N-α-[methyl-3H]-, 250µCi (9.25MBq)

(R)-α-methylhistamine dihydrochloride, tritiated on the methyl group. α-Methylhistamine is a histamine agonist selective for the histamine H3 receptor.
List Price : 875.00 GBP

Butyl Bicyclophosphorothionate, Tertiary-[35S]

Tertiary-Butylbicyclophosphorothionate (TBPS), radiolabeled with S-35. TBPS is a GABAA receptor antagonist.
Price Range : 1600.00 GBP - 2830.00 GBP
Adenosine 5 Triphosphate 250 µCi

Pyrilamine (Mepyramine), [pyridinyl 5-3H]-, 250µCi (9.25MBq)

Pyrilamine (Mepyramine), tritiated at the pyridinyl 5 position. Pyrilamine acts as an antagonist at the histamine H1 receptor.
List Price : 1260.00 GBP
Adenosine 5 Triphosphate 250 µCi

5-Hydroxytryptamine Creatinine Sulfate, [1,2-3H(N)]

5-Hydroxytryptamine Creatinine Sulfate (Serotonin, 5-HT), tritiated at the 1,2 position. 5-Hydroxytryptamine is a neurotransmitter and is the endogenous ligand for serotonin receptors.
Price Range : 597.00 GBP - 1610.00 GBP
Diclofenac sodium- Phenylacetic acid C14

Ascorbic Acid, L-[1-14C]-,>97%, 50µCi (1.85MBq)

L-Ascorbic acid (reduced form of vitamin C; ascorbate), labeled with C-14 at the 1- position. L-ascorbic acid is a vitamin that binds and is transported through sodium-dependent vitamin C transporters (SVCT1 and SCVT2).
List Price : 730.00 GBP
Adenosine 5 Triphosphate 250 µCi

DOFETILIDE, [N-METHYL-3H], 100 µCi

Dofetilide, tritiated at the N-methyl position. Dofetilide is a selective potassium channel (hERG) blocker.
List Price : 1260.00 GBP
Adenosine 5 Triphosphate 250 µCi

Cytisine HCl, [3,5-3H(N)]

Cytisine HCl, [3,5-3H(N)]- will have fresh lot dates on the second Monday in April.
Price Range : 476.00 GBP - 1710.00 GBP
Adenosine 5 Triphosphate 250 µCi

Methyl-4-Phenylpyridinium Acetate, N-[Methyl-3H]-, MPP (+)

N-Methyl-4-phenylpyridinium (MPP+) acetate, tritiated on the methyl group. MPP+ is a substrate for the organic cation ion transporter (OCT), the dopamine transporter (DAT), the norepinephrine transporter (NET), and the serotonin transporter (SERT).
Price Range : 410.00 GBP - 1090.00 GBP
Adenosine 5 Triphosphate 250 µCi

Escitalopram, [N-methyl-3H]-

Escitalopram (Cipralex), tritiated at the N-methyl position. Escitalopram is a selective serotonin reuptake inhibitor (SSRI) with high selectivity for the serotonin transporter (SERT) compared to the norepinephrine transporter (NET).
List Price : 3580.00 GBP
Adenosine 5 Triphosphate 250 µCi

Propranolol, L-[4-3H]-, 250µCi (9.25MBq)

L-propranolol, tritiated at the 4 position. Propranolol is a non-selective beta blocker that acts as a potent antagonist for β-adrenoceptors.
List Price : 1050.00 GBP
Adenosine 5 Triphosphate 250 µCi

GR125743, [N-METHYL-3H]

GR125743, tritiated on the N-methyl group. GR125743 acts as an antagonist at serotonin 5-HT1B and 5-HT1D receptors.
List Price : 1450.00 GBP
Adenosine 5 Triphosphate 250 µCi

Ifenprodil, [Phenyl-3H]-, 250µCi (9.25MBq)

Ifenprodil, tritiated on the phenyl group. Ifenprodil acts as an antagonist at the N-methyl-D-aspartate (NMDA) receptor.
List Price : 1590.00 GBP

"Ligands" 1-50 of 119 Products and Services

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