PerkinElmer

Metabolic Disease

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Metabolic diseases like diabetes are increasingly widespread, and research for this class of diseases relies on discovering and quantifying biomarkers to elucidate underlying mechanisms and uncover novel drug targets. Our portfolio of metabolic assays are well suited for metabolic disease research in vitro, in vivo, and in situ, and offer novel tools for your research workflow from start to finish.

Metabolic diseases are systemic and manifest with a variety of biological changes, from autophagy dysfunction to altered blood coagulation. For easy detection of a wide range of metabolic biomarkers, we offer fast and pre-validated metabolic assay reagents, kits, and imaging systems. For targeted binding studies, we also provide target-specific radiolabeled reagents.

Our products for metabolic disease research include:

  • LANCE® TR-FRET technology
  • AlphaLISA® immunoassay kits
  • Alpha reagents for AlphaLISA
  • DELFIA® TRF technology
  • Cellular, tissue, and in vivo imaging systems
  • Target-specific radiolabeled ligands, carbohydrates, lipids, and steroids

The range of tools offered allows for the detection and quantitation of many key biomolecules in metabolic disease research. Gain precise insight on disease biomarkers like c-reactive protein, fibrinogen, IGF, FGF, insulin and glucagon, leptin and ghrelin, adiponectin, and factor VIII.

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Product Type
  • Instruments (1)
  • Reagents (140)
  • Software and Informatics (4)
Assay Target
  • Adiponectin (3)
  • Albumin (5)
  • ApoA1 (4)
  • ApoB (2)
  • ApoC3 (2)
  • ApoE (2)
  • AST (1)
  • BMP-9 (1)
  • C-peptide (2)
  • CCL2 (1)
  • Corticosterone (2)
  • Cortisol (3)
  • Factor VIII (1)
  • FSH (3)
  • Ghrelin (4)
  • GLP-1 (2)
  • Glucagon (3)
  • Growth Hormone (1)
  • hCG (3)
  • HO-1 (1)
  • HO-2 (1)
  • IGF1 (5)
  • IGF2 (1)
  • Insulin (4)
  • KIM-1 (1)
  • LDH (1)
  • Leptin (5)
  • MANF (2)
  • MBNL1 (1)
  • NNMT (1)
  • Osteoprotegerin (1)
  • PCSK9 (1)
  • PIGF (1)
  • PON1 (1)
  • PON2 (1)
  • Progesterone (1)
  • PSMA (2)
  • SHP2 (1)
  • Somatostatin (1)
  • Testosterone (1)
  • TSH (4)
  • Utrophin (1)
Target Species
  • Human (76)
  • Mouse (5)
  • Rat (4)
Application
  • Protein Analysis & Detection (82)
Therapeutic Area
  • Angiogenesis (1)
  • Biologics/Bioprocess (4)
  • Cancer (4)
  • Central Nervous System (1)
  • Inflammation (4)
  • Metabolic (62)
Product Brand Name
  • AlphaLISA (53)
  • AlphaPlex (2)
  • LANCE Ultra (28)
  • Membrane Target Systems (1)
  • NEN Radiochemicals (54)
  • Quantum (1)
Detection Method
  • Alpha (55)
  • Radiometric (55)
  • Time-Resolved Fluorescence (TRF) (25)
  • TR-FRET (25)
Receptor Type
  • Ghrelin (1)
Assay Validated
  • Binding (1)
Radioisotope
  • C-14 (27)
  • H-3 (28)
Radionuclide
  • 14C (27)
  • 3H (28)
Label Position
  • Generally Labeled (2)
  • Nominally Labeled (17)
  • Specifically Labeled (25)
  • Uniformly Labeled (11)
Buffer
  • Aqueous (10)
  • Aqueous PT6-271 Stabilizer (2)
  • Ethanol : water (10)
Assay points(200-50,000)
  • 100 (28)
  • 10000 (16)
  • 500 (55)
  • 5000 (40)
Assay Target Class
  • Cytokine (1)
  • GPCR (1)
  • Hormone (37)
  • Peptide (5)
  • Protein (42)
Automation Compatible
  • Yes (84)
Concentration
  • 0.02 mCi/mL (1)
  • 0.05 mCi/mL (1)
  • 0.1 mCi/mL (11)
  • 0.2 mCi/mL (4)
  • 1 mCi/mL (17)
Experimental Type
  • In vitro (70)
Format
  • Microplates (67)
Host Cell
  • CHO-K1 (1)
Imaging Modality
  • microCT Imaging (1)
Length
  • 901-1000 (1)
Pipetting Arms
Volume
  • 0-50 (15)
  • 201-250 (4)

"Metabolic Disease" 1-50 of 145 Products & Services

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Quantum GX2 microCT imaging system

Quantum GX2 microCT Imaging System

Image beyond bone – into oncology, cardiovascular and pulmonary diseases, and much more, with the Quantum GX2 microCT imaging system. With the Quantum GX2, flexibility is key. Combining the ability to perform high speed, low dose scans, ideal for longitudinal studies, across multiple species (mice, rats, rabbits) with high resolution ex vivo scanning, the Quantum GX2 microCT imaging system offers the flexibility and performance you need to not just image, but further understand your disease models.
AlphaLISA immunoassay kits

Insulin-like Growth Factor 2 (human) AlphaLISA Detection Kit

The AlphaLISA® Human Insulin-like Growth Factor 2 (IGF2) Detection Kit is designed for detection and quantitation of human IGF2 in serum, buffered solution or cell culture medium in a homogeneous (no-wash steps, no separation steps) assay.
Price Range : 1040.00 GBP - 6930.00 GBP
LANCE Detection Kit

Apo-CIII (human) LANCE Ultra TR-FRET Detection Kit

The LANCE® Ultra Human Apo-CIII Detection Kit is designed for detection and quantitation of ApoC3 in buffered solution and cell culture media using a homogeneous TR-FRET (no-wash steps, no separation steps) assay.
Price Range : 531.00 GBP - 7070.00 GBP
Adenosine 5 Triphosphate 250 µCi

Mannose, D-[2-3H(N)]-, Specific Activity: 15-30Ci (555GBq-1.11TBq)/mmol, 5mCi (185MBq)

5 mCi quantities of D-[2-3H(N)]-Mannose are available for your research.
List Price : 2500.00 GBP

Leptin (human) LANCE Ultra TR-FRET Detection Kit

The LANCE® Ultra Human Leptin Detection Kit is designed for detection and quantitation of human leptin in cell culture media using a homogeneous TR-FRET (no-wash steps, no separation steps) assay.
Price Range : 547.00 GBP - 7260.00 GBP

Heme oxygenase 1 AlphaLISA Detection Kit

The AlphaLISA® immunoassay kit for human heme oxygenase 1 (HO-1) enables the quantitative determination of human HO-1 in serum, buffered solution, and cell culture supernatants using a homogeneous AlphaLISA assay (no wash steps).
Price Range : 297.00 GBP - 6510.00 GBP
alphaimmunoassay1

Growth Hormone (human) AlphaLISA Detection Kit

The AlphaLISA® Human Growth Hormone Detection Kit is designed for detection and quantitation of human growth hormone in serum, buffered solution or cell culture medium in a homogeneous (no-wash steps, no separation steps) assay.
Price Range : 1110.00 GBP - 6930.00 GBP
Protein

ApoE (human), lyophilized (LANCE)

Human ApoE standard, for use in running standard curves in LANCE Ultra TR-FRET assays. This standard is already provided in the LANCE Ultra ApoE Detection Kit, but can also be ordered separately.
List Price : 203.00 GBP
AlphaLISA assay principle

Ghrelin (active) (human) AlphaLISA Detection Kit

The AlphaLISA® immunoassay kit for active human ghrelin enables the quantitative determination of active ghrelin in serum, buffered solution, and cell culture supernatants using a homogeneous AlphaLISA assay (no wash steps).
Price Range : 412.00 GBP - 12360.00 GBP
Adenosine 5 Triphosphate 250 µCi

Inositol, Myo,-[2-3H(N)]-, Ethanol/Water

Myo-inositol, labeled with tritium. This product is supplied in 90% ethanol. Tritiated myoinositol is commonly used to label lipids.
Price Range : 1330.00 GBP - 3330.00 GBP

PIGF (human) AlphaLISA Detection Kit

The AlphaLISA® immunoassay kit for human placental growth factor (PIGF) enables the quantitative determination of human PIGF (PGF) in serum, buffered solution, and cell culture supernatants using a homogeneous AlphaLISA assay (no wash steps).
Price Range : 297.00 GBP - 6510.00 GBP
Diclofenac sodium- Phenylacetic acid C14

Methyl-D-glucose, 3-O-[Methyl-14C]

3-O-methyl-D-glucose, labeled on the methyl group with C-14. 3-O-methyl-D-glucose (OMG) is a glucose analog that is readily transported into most cells, but does not become phosphorylated and therefore will equilibrate across the cell membrane. Equilibrium is usually reached rapidly, so glucose uptake assays may only be linear for a short period of time; you may need to take your measurements fairly quickly. This analog cannot be further metabolized by cells.
Price Range : 680.00 GBP - 2120.00 GBP
Protein

GLP-1 (7-36) (human), lyophilized (LANCE)

Human GLP-1 (7-36) standard, lyophilized, for use in running standard curves in LANCE TR-FRET no-wash detection assays. This standard is already provided in the LANCE Ultra Human GLP-1 (7-36) TR-FRET Detection Kit, but can be ordered separately.
List Price : 165.00 GBP
Adenosine 5 Triphosphate 250 µCi

Inulin, Methoxy-, [Methoxy-3H]

Methoxy-inulin, labeled on methoxy groups with tritium. 3H-methoxyinulin is commonly used to measure glomerular fitration rates (GFR) or as an extracellular space marker.
Price Range : 497.00 GBP - 1570.00 GBP
Adenosine 5 Triphosphate 250 µCi
List Price : 2820.00 GBP
AlphaLISA immunoassay kits

ApoB (human) AlphaLISA Detection Kit

The AlphaLISA® immunoassay kit for human ApoB enables the quantitative determination of human apolipoprotein B in serum, buffered solution, and cell culture supernatants using a homogeneous AlphaLISA assay (no wash steps).
Price Range : 412.00 GBP - 12360.00 GBP
AlphaLISA immunoassay kits

Adiponectin (human) AlphaLISA Detection Kit

The AlphaLISA® Human Adiponectin Detection Kit is designed for detection and quantitation of human adiponectin in serum, buffered solution or cell culture medium in a homogeneous (no-wash steps, no separation steps) assay.
Price Range : 1040.00 GBP - 6930.00 GBP
AlphaLISA immunoassay kits

Glucagon (human) AlphaLISA Detection Kit

The AlphaLISA® Glucagon Detection Kit is designed for detection and quantitation of glucagon in cell culture media, sera and plasma, in a homogeneous (no-wash steps, no separation steps) assay.
Price Range : 478.00 GBP - 6630.00 GBP

Testosterone AlphaLISA Detection Kit

The AlphaLISA® Testosterone Research Kit is designed for detection and quantitation of testosterone in serum, buffered solution or cell culture medium in a homogeneous (no-wash steps, no separation steps) assay.
Price Range : 443.00 GBP - 6900.00 GBP
LANCE Detection Kit

ApoA1 (human) LANCE Ultra TR-FRET Detection Kit

The LANCE® Ultra Human ApoA1 Detection Kit is designed for detection and quantitation of human Apolipoprotein A1 (ApoA1) in buffered solution and cell culture media using a homogeneous TR-FRET (no-wash steps, no separation steps) assay.
Price Range : 531.00 GBP - 7070.00 GBP
AlphaLisa Analyte 2

Corticosterone (human), liquid (AlphaLISA)

Human corticosterone standard, for use in running standard curves in AlphaLISA assays. This standard is already provided in the AlphaLISA human Corticosterone Detection Kit, but can also be ordered separately.
List Price : 160.00 GBP
AlphaLISA immunoassay kits

Heme oxygenase 2 AlphaLISA Detection Kit

The AlphaLISA® immunoassay kit for human heme oxygenase 2 (HO-2) enables the quantitative determination of human HO-2 in serum, buffered solution, and cell culture supernatants using a homogeneous AlphaLISA assay (no wash steps).
Price Range : 297.00 GBP - 6510.00 GBP
Adenosine 5 Triphosphate 250 µCi

Glucosamine Hydrochloride, D-[6-3H(N)]-, Aqueous solution, Specific Activity: 20-45Ci (740GBq-1.66TBq)/mmol, 250µCi (9.25MBq)

250 µCi quantities of tritiated D-glucosamine hydrochloride are available for your research.
List Price : 367.00 GBP
AlphaLISA immunoassay kits

FSH (human) AlphaLISA Detection Kit

The AlphaLISA® immunoassay kit for human FSH enables the quantitative determination of human follicle stimulating hormone in serum, buffered solution, and cell culture supernatants using a homogeneous AlphaLISA assay (no wash steps).
Price Range : 356.00 GBP - 10690.00 GBP
LANCE Detection Kit

PCSK9 (human) LANCE Ultra TR-FRET Detection Kit

The LANCE® Ultra Human PCSK9 Detection Kit is designed for detection and quantitation of human Proprotein Convertase Subtilisin/Kexin Type 9 in cell culture media using a homogeneous TR-FRET (no-wash steps, no separation steps) assay.
Price Range : 546.00 GBP - 7280.00 GBP
Protein

Apo-CIII (human), lyophilized (LANCE)

Human Apo-CIII standard, for use in running standard curves in LANCE Ultra TR-FRET assays. This standard is already provided in the LANCE Ultra ApoC3 Detection Kit, but can also be ordered separately.
List Price : 160.00 GBP
AlphaLisa Analyte 2

ApoA1 (human) Iyophilized (AlphaLISA)

Human Apo1A standard, lyophilized, for use in running standard curves in AlphaLISA no-wash immunoassays. This standard is already provided in the AlphaLISA Apo1A Detection Kit, but can be ordered separately.
List Price : 209.00 GBP

Total Ghrelin (human) AlphaLISA Detection Kit

The AlphaLISA® immunoassay kit for human total ghrelin enables the quantitative determination of total ghrelin in serum, plasma, and cell culture supernatants using a homogeneous AlphaLISA assay (no wash steps).
Price Range : 412.00 GBP - 12360.00 GBP
Diclofenac sodium- Phenylacetic acid C14

Glucose, D-[14C(U)]-

5 mCi quantities of D-[14C(U)]-Glucose are available for your research.
List Price : 4960.00 GBP
AlphaLISA immunoassay kits

Somatostatin (human) AlphaLISA Detection Kit

The AlphaLISA® Somatostatin Detection Kit is designed for detection and quantitation of somatostatin in serum, buffered solution or cell culture medium in a homogeneous (no-wash steps, no separation steps) assay.
Price Range : 477.00 GBP - 6890.00 GBP
Adenosine 5 Triphosphate 250 µCi

Glucose, D-[5-3H(N)]-, 1mCi (37MBq)

1 mCi quantities of D-[5-3H(N)]-Glucose are available for your research. 
List Price : 1110.00 GBP
Adenosine 5 Triphosphate 250 µCi

Glucose, D-[6-3H(N)]

D-glucose, labeled with tritium at C6. This product is supplied in 90% ethanol. D-glucose can be used for metabolic studies and glucose uptake.
Price Range : 452.00 GBP - 1650.00 GBP
AlphaLISA immunoassay kits

Insulin (human) AlphaLISA Detection Kit

The AlphaLISA® immunoassay kit for human insulin enables the detection and quantitation of insulin in serum, buffered solution or cell culture medium using a homogeneous AlphaLISA assay (no wash steps). The antibodies in the kit are mouse monoclonal antibodies (clone numbers 8E2 and 3A6).
Price Range : 1040.00 GBP - 6930.00 GBP
AlphaLISA assay principle

MANF (human) AlphaLISA Detection Kit

The AlphaLISA® immunoassay kit for human MANF enables the quantitative determination of mesencephalic astrocyte-derived neurotrophic factor (MANF) in human serum, plasma, and cell culture supernatants using a homogeneous AlphaLISA assay (no wash steps).
Price Range : 424.00 GBP - 12730.00 GBP
AlphaLISA immunoassay kits

KIM-1 (human) AlphaLISA Detection Kit

The AlphaLISA® immunoassay kit for human Kidney Injury Molecule 1 (KIM-1) enables the quantitative determination of human KIM-1 in buffered solution, urine, cell culture media, and cell lysates using a homogeneous AlphaLISA assay (no wash steps).
Price Range : 500.00 GBP - 9600.00 GBP
AlphaLISA immunoassay kits

PSMA (human) AlphaLISA Detection Kit

The AlphaLISA® immunoassay kit for human PSMA enables the quantitative determination of human prostate specific membrane antigen (PSMA) in buffered solution and cell culture supernatants using a homogeneous AlphaLISA assay (no wash steps).
Price Range : 412.00 GBP - 9890.00 GBP
Diclofenac sodium- Phenylacetic acid C14

Sucrose, [14C(U)]-Specific Activity: 400-700mCi (14.8-25.9GBq)/mmol, 250µCi (9.25MBq)

250 µCi quantities of [14C(U)]-Sucrose are available for your research.
List Price : 909.00 GBP
AlphaLISA immunoassay kits

Corticosterone (human) AlphaLISA Detection Kit

The AlphaLISA® immunoassay kit for human corticosterone enables the quantitative determination of corticosterone in serum, buffered solution, and cell culture supernatants using a homogeneous AlphaLISA assay (no wash steps).
Price Range : 297.00 GBP - 6510.00 GBP
AlphaLISA immunoassay kits

AST (human) AlphaLISA Detection Kit

The AlphaLISA® immunoassay kit for human AST enables the quantitative determination of human aspartate transaminase (AST) in buffered solution, cell culture media, and serum using a homogeneous AlphaLISA assay (no wash steps).
Price Range : 500.00 GBP - 9600.00 GBP
Diclofenac sodium- Phenylacetic acid C14

Glucose, D-[6-14C]

50 µCi quantities of D-[6-14C]-Glucose are available for your research
List Price : 639.00 GBP
Diclofenac sodium- Phenylacetic acid C14

Deoxy-D-glucose, 2-[1-14C]-, Aqueous Solution/Steri-packaged

2-Deoxy-D-glucose, labeled with carbon-14 at C1. This product is supplied steri-packaged in an aqueous solution. Deoxy-D-glucose (DOG) is a glucose analog that is readily transported into most cells, is phosphorylated and trapped by the cells (unidirectional transport), and cannot be further metabolized. It is the most-common chemical used in glucose uptake assays.
Price Range : 799.00 GBP - 3170.00 GBP
Protein

TSH (human), lyophilized (AlphaLISA)

Human thyroid stimulating hormone (TSH) standard, for use in running standard curves in AlphaLISA assays. This standard is already provided in the AlphaLISA human TSH detection kit, but can also be ordered separately.
List Price : 209.00 GBP
Diclofenac sodium- Phenylacetic acid C14

Inulin, Carboxyl-, [Carboxyl-14C]

Inulin-carboxyl, labeled on carboxyl groups with C-14. Inulin-carboxyl-14C is commonly used in renal cearance studies.
Price Range : 405.00 GBP - 2010.00 GBP

hCG (human) AlphaLISA Detection Kit

The AlphaLISA® immunoassay kit for human chorionic gonadotropin (hCG) enables the quantitative determination of hCG in serum, buffered solution, and cell culture supernatants using a homogeneous AlphaLISA assay (no wash steps).
Price Range : 356.00 GBP - 10690.00 GBP
LANCE Detection Kit

CCL2 (human) LANCE Ultra TR-FRET Detection Kit

The LANCE® Ultra Human CCL2/MCP-1 Detection Kit is designed for detection and quantitation of human CCL2/MCP-1 in cell culture media using a homogeneous TR-FRET (no-wash steps, no separation steps) assay.
Price Range : 547.00 GBP - 7260.00 GBP
AlphaLISA immunoassay kits

PON-1 (human) AlphaLISA Detection Kit

The AlphaLISA® immunoassay kit for human paraoxonase/arylesterase 1 (PON-1) enables the quantitative determination of human PON-1 in buffered solution, serum, cell culture media, and cell lysates using a homogeneous AlphaLISA assay (no wash steps).
Price Range : 500.00 GBP - 9600.00 GBP
AlphaPlex Terbium immunoassay kits

AlphaPlex™ 545 Human Insulin Detection Kit

The AlphaPlex™ 545 (Terbium) Human Insulin Detection Kit is designed for the quantitative determination of human Insulin together with another analyte (AlphaLISA) in serum, buffered solution or cell culture medium using a homogeneous assay.
Price Range : 316.00 GBP - 6890.00 GBP
Diclofenac sodium- Phenylacetic acid C14

Glucose, D-[14C(U)]-, Specific Activity: 250-360 mCi/mmol

D-glucose, uniformly labeled with C-14. This product is supplied in 90% ethanol. D-glucose can be used for metabolic studies and glucose uptake.
Price Range : 475.00 GBP - 1690.00 GBP
Adenosine 5 Triphosphate 250 µCi

Inositol, Myo, -[2-3H(N)]-, Specific Activity: 10-25Ci (370-925GBq)/mmol, 250µCi (9.25MBq)

250 µCi quantities of Myo-[2-3H(N)]-Inositol are available for your research.
List Price : 533.00 GBP
AlphaLISA immunoassay kits

Factor VIII (human) AlphaLISA Detection Kit

The AlphaLISA® Human Factor VIII Detection Kit is designed for detection and quantitation of Human Factor VIII in human serum, plasma, and cell culture supernatants using a homogeneous (no-wash steps, no separation steps) assay.
Price Range : 443.00 GBP - 6900.00 GBP

"Metabolic Disease" 1-50 of 145 Products & Services

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