PerkinElmer

Protein-protein Interaction

OF

Accurately measure the function of proteins and gain new insights into protein-protein interaction (PPI) to modulate cellular processes. Inhibition and stabilization of these interactions using small molecules provides a mechanism that can be targeted for drug discovery.

We offer the technology to measure protein-protein interaction such as:

  • Transient and stable interactions
  • Low-to-high affinity interactions (pM to mM affinity)
  • Full-length protein-protein binding
  • Peptide-protein
  • Receptor dimerization
  • Protein-small molecule
  • Protein complex interactions

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Product Type
  • Accessories (6)
  • Instruments (6)
  • Reagents (121)
Antibody conjugates
  • Anti-6X His (7)
  • Anti-bovine IgA (1)
  • Anti-c-Myc (4)
  • Anti-C-tag (3)
  • Anti-DIG (2)
  • Anti-DNP (2)
  • Anti-FITC (3)
  • Anti-FLAG (6)
  • Anti-GFP (2)
  • Anti-goat IgG (1)
  • Anti-GST (5)
  • Anti-HA (4)
  • Anti-HRP (2)
  • Anti-human IgG (3)
  • Anti-MBP (1)
  • Anti-mouse IgG (3)
  • Anti-rabbit IgG (2)
  • Anti-rat IgG (2)
  • Anti-V5 (3)
  • Glutathione (3)
  • Nickel chelate (1)
  • Protein A (4)
  • Protein G (1)
  • Protein L (1)
  • Strep-Tactin (1)
  • Streptavidin (11)
  • Streptavidin/Anti-c-Myc (1)
  • Streptavidin/Anti-DIG (1)
  • Streptavidin/Anti-FITC (1)
  • Streptavidin/Anti-FLAG (1)
  • Streptavidin/Anti-GST (1)
  • Streptavidin/Anti-HA (1)
  • Streptavidin/Anti-mouse IgG (1)
  • Streptavidin/Anti-rabbit IgG (1)
  • Streptavidin/Nickel chelate (1)
  • Streptavidin/Protein A (1)
  • Unconjugated (2)
Application
  • Antibody binding (1)
  • Enzymatic (5)
  • Isotyping (1)
  • Multiplexing (2)
  • Protein Analysis & Detection (46)
  • Protein-nucleic acid interactions (4)
  • Protein-protein interactions (91)
Assay Points
  • 100 (5)
  • 10000 (11)
  • 500 (30)
  • 5000 (19)
  • 50000 (10)
Assay Target
  • COX-2 (3)
  • EGF (2)
  • EGFR (3)
  • FCGR3A (4)
  • Histone H4 (14)
  • MMP-7 (3)
  • PD-1 (3)
  • PD-L1 (4)
Assay Target Class
  • Fc-receptor (4)
  • Histone (14)
  • Protein (13)
Automation Compatible
  • Yes (124)
Detection Method
  • Absorbance (5)
  • Alpha (79)
  • DELFIA TRF (7)
  • Fluorescence (5)
  • Fluorescence Polarization (3)
  • Image-based Cytometry (1)
  • Label-free (2)
  • Luminescence (5)
  • Time-Resolved Fluorescence (TRF) (31)
  • TR-FRET (19)
Experimental type
  • In vitro (98)
Fluorophore
  • Eu-N1 (5)
  • Eu-W1024 (9)
  • Eu-W8044 (1)
  • Sm-N1 (1)
  • SureLight APC (4)
  • Tb-N1 (1)
  • ULight (8)
Format
  • Microplates (104)
Maximum Temperature (Celsius)
  • 40-50 (2)
  • 50-60 (2)
Molecular modification
  • Acetylation (14)
Product Brand Name
  • Alpha (6)
  • AlphaLISA (52)
  • AlphaPlex (16)
  • AlphaScreen (11)
  • DELFIA (7)
  • EnSight (1)
  • EnSpire (3)
  • EnVision (3)
  • LANCE (10)
  • LANCE SureLight (4)
  • LANCE Ultra (11)
  • Victor (3)
  • ViewLux (1)
Target Species
  • Human (17)
Therapeutic Area
  • Biologics/Bioprocess (4)
  • Cancer (13)
  • Epigenetics (14)
Volume
  • 0-50 (47)
  • 201-250 (32)
  • 451-500 (10)
  • Over 500 (10)

"Protein-protein Interaction" 1-50 of 133 Products and Services

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EnSpire Alpha Plate Reader

The EnSpire Alpha Plate Reader provides proven Alpha technology to your lab at an affordable price and from the Alpha detection leader.
VictorX_ImageA_320px

VICTOR Multilabel Plate Reader

The next generation VICTOR X Multilabel Plate Reader platform delivers flexibility, speed and performance to research labs of all sizes.
EnSight multimode plate-reader

EnSight Multimode Plate Reader

The EnSight multimode plate reader combines labeled, label-free & image-based cytometry technologies in a single benchtop platform. Imaging & online data analysis is fast: a 384-well plate can be imaged in less than 5 mins. The system’s modular design, combined with workflow-based Kaleido data acquisition & analysis software, gives a truly versatile plate reader that gets users productive quickly.

EnSpire Multimode Plate Reader

EnSpire® Multimode Plate Reader is designed to meet the demands of multi-user research environments, providing high performance technology and flexibility for a range of applications without compromising sensitivity. Combine this with our expertise and portfolio of reagents, PerkinElmer offers an unrivaled solution to your application needs.
EnVision_Alone_Left_Angle

EnVision Multilabel Reader

The EnVision Multilabel Plate Reader provides the highest speed, ultra-high throughput, and maximum sensitivity across  all detection technologies, so that your high throughput screening applications won’t be held back by unreliable results or equipment that can’t keep up to the demands of escalating workloads and new assays.

ViewLux uHTS Microplate Imager

The ViewLux® is the gold standard, ultra high-speed microplate imager, ideal for high throughput screening of compound libraries requiring the ultimate in speed, reliability and high quality data.
PerkinElmer

LANCE Eu-W1024 Anti-6xHis

Europium-labeled anti-6X His antibody, for capturing His-tagged proteins in LANCE® TR-FRET assays.
Price Range : 141.00 GBP - 6670.00 GBP
PerkinElmer

Anti-GST AlphaLISA Acceptor Beads

AlphaLISA® Acceptor beads conjugated to anti-GST antibody. These beads can be used to capture GST-tagged proteins and peptides in AlphaLISA no-wash assays.
Price Range : 369.00 GBP - 15130.00 GBP
Alpha donor antibody coated

Anti-DIG Alpha Donor beads

Alpha Donor beads conjugated to anti-DIG (digoxin) antibody. This bead can be used to capture Dig-labeled biomolecules for Alpha no-wash assays.
Price Range : 302.00 GBP - 5480.00 GBP

AlphaScreen C-MYC Detection Kit

AlphaScreen® no-wash assay kit containing Streptavidin Donor beads and Anti-c-myc-conjugated AlphaScreen Acceptor beads. This kit contains enough reagents to run 500 wells in 384-well format, using a 25 µL reaction volume.
Price Range : 113.00 GBP - 8640.00 GBP

Anti-HRP AlphaLISA Acceptor Beads

AlphaLISA® Acceptor beads conjugated to anti-HRP antibody. These beads can be used to capture HRP-fusion proteins for AlphaLISA no-wash assays.
Price Range : 358.00 GBP - 14710.00 GBP

AlphaScreen Mouse IgG Detection Kit

AlphaScreen® no-wash assay kit containing Streptavidin Donor beads and Anti-mouse IgG conjugated AlphaScreen Acceptor beads.
Price Range : 113.00 GBP - 8640.00 GBP

ULight anti-FLAG

ULight™ labeled anti-FLAG antibodies for LANCE® TR-FRET assays. The anti-FLAG antibody is a purified mouse IgG2a monoclonal antibody (clone 29E4.G7.H11). The antibody is know to recognize C-terminal and N-terminal FLAG-tagged proteins.
Price Range : 273.00 GBP - 6660.00 GBP
PerkinElmer

LANCE Eu-W1024 Anti-c-Myc

Europium-labeled anti-c-myc antibody, for capturing c-myc-tagged proteins in LANCE® TR-FRET assays.
Price Range : 141.00 GBP - 8570.00 GBP

ULight anti-c-myc antibody

ULight labeled anti-c-myc antibody for LANCE® TR-FRET assays.
Price Range : 268.00 GBP - 6790.00 GBP

AlphaScreen FITC (Fluorescein) Detection Kit

AlphaScreen® no-wash assay kit containing Streptavidin Donor beads and Anti-FITC conjugated AlphaScreen Acceptor beads. 
Price Range : 113.00 GBP - 8640.00 GBP
AlphaLisa Analyte 2

Biotinylated Human FCGR3A (176Val), lyophilized (AlphaLISA)

Biotinylated human FCGR3A (176Val) receptor. For use in AlphaLISA® no-wash assays.
List Price : 166.00 GBP

LANCE Ultra ULight™-anti-6xHis

Mouse monoclonal anti-polyHistidine tag antibody labeled with ULight™ dye.
Price Range : 263.00 GBP - 6670.00 GBP

AlphaScreen FLAG (M2) Detection Kit

AlphaScreen® no-wash assay kit containing Streptavidin Donor beads and Anti-FLAG conjugated AlphaScreen Acceptor beads. 
Price Range : 113.00 GBP - 8640.00 GBP
PerkinElmer

AlphaLISA BRD4_BD1 / H4 K5,12Ac Binding Kit

This kit is designed for the detection of binding activity between bromodomain-containing protein 4, Bromodomain1: BRD4 (BD1) and acetylated histone H4 peptide (H4 K5,12Ac) using a homogeneous AlphaLISA assay (no wash steps). The assay allows screening of BRD4 inhibitors with a highly-specific substrate.
Price Range : 490.00 GBP - 2610.00 GBP

ULight Anti-C-tag

ULight™ labeled anti-C-tag antibodies for LANCE® TR-FRET assays. This mouse monoclonal IgG1 antibody recognizes N-terminal and C-terminal Protein C tagged fusion proteins. The anti-C-tag antibody can be used to capture C-tag proteins, and can be used in conjunction with LANCE Europium-labeled reagents to create LANCE TR-FRET assays.
Price Range : 273.00 GBP - 6660.00 GBP

AlphaScreen Histidine (Nickel Chelate) Detection Kit

AlphaScreen® no-wash assay kit containing Streptavidin Donor beads and nickel chelate (Ni-NTA) AlphaScreen Acceptor beads. This kit contains enough reagents to run 500 wells in 384-well format, using a 25 µL reaction volume.
Price Range : 113.00 GBP - 8640.00 GBP
PerkinElmer

AlphaLISA BRD4_BD2 / H4 K5,8,12,16Ac Binding Kit

This kit is designed for the detection of binding activity between bromodomain-containing protein 4, Bromodomain2: BRD4 (BD2) and acetylated histone H4 peptide (H4 K5,8,12,16Ac) using a homogeneous AlphaLISA assay (no wash steps). The assay allows screening of BRD4 inhibitors with a highly-specific substrate.
Price Range : 490.00 GBP - 2610.00 GBP
PerkinElmer

LANCE Eu-W1024 anti-FLAG

Eu-W1024 labeled anti-FLAG antibodies for LANCE® TR-FRET assays. The anti-FLAG antibody is a purified mouse IgG2a monoclonal antibody (clone 29E4.G7.H11). The antibody is know to recognize C-terminal and N-terminal FLAG-tagged proteins.
Price Range : 200.00 GBP - 5660.00 GBP

Strep-Tactin® AlphaLISA® Acceptor beads

AlphaLISA® Acceptor beads conjugated to Strep-Tactin®. These beads can be used to capture Strep-tag® II-tagged proteins for AlphaLISA no-wash assays.
Price Range : 358.00 GBP - 14710.00 GBP
Alpha Fc receptor bind

FCGR3A/CD16a (176Val/V158) AlphaLISA Binding Kit, 5,000 Assay Points

This kit is designed for the detection of binding activity between human FCGR3A (176Val) and human IgG Fc fragment using a homogeneous AlphaLISA® assay (no wash steps). This assay can facilitate the design and development of antibody therapetics by using competitive binding.
List Price : 6660.00 GBP
PerkinElmer

LANCE Eu-W1024 Anti-HA

Europium-labeled anti-HA antibody, for capturing HA-tagged proteins and peptides in LANCE® TR-FRET assays.
Price Range : 623.00 GBP - 8330.00 GBP

Anti-human IgG (Fc specific) AlphaLISA Acceptor Beads

AlphaLISA® Acceptor beads conjugated to anti-human IgG antibody. These beads can be used to capture human IgG antibodies. The antibody conjugated to these beads is Fc-specific, and is a mouse polyclonal antibody.
Price Range : 369.00 GBP - 15140.00 GBP

DELFIA Sm-N1 Streptavidin

Samarium-labeled streptavidin for binding biotinylated biomolecules in DELFIA® time-resolved fluorescence (TRF) assays.
Price Range : 183.00 GBP - 1250.00 GBP

ULight anti-FITC

ULight™ labeled anti-FITC antibody for LANCE® TR-FRET assays. The anti-FITC antibody is a purified mouse IgG2a monoclonal antibody.
Price Range : 268.00 GBP - 6790.00 GBP

Protein A AlphaLISA Acceptor Beads

AlphaLISA® Acceptor beads conjugated to Protein A. These beads can be used to capture antibodies that associate with Protein A.
Price Range : 369.00 GBP - 15140.00 GBP
AlphaLISA immunoassay kits

FCGR3A/CD16a (176Val/V158) AlphaLISA Binding Kit, 500 Assay Points

This kit is designed for the detection of binding activity between human FCGR3A (176Val) and human IgG Fc fragment using a homogeneous AlphaLISA® assay (no wash steps). This assay can facilitate the design and development of antibody therapetics by using competitive binding.
List Price : 1160.00 GBP
Alphaplex_545_protein_coated

Streptavidin AlphaPlex™ 545 Acceptor Beads

Streptavidin-coated AlphaPlex™ 545 (Terbium) Acceptor beads, for use in Alpha no-wash multiplexing assays.
Price Range : 369.00 GBP - 15130.00 GBP
AlphaLISA Bromodomain Binding Assay kits

AlphaLISA BRD4 (BD2) and H4 K5Ac Binding Assay Kit

This kit is designed for the detection of binding activity between bromodomain-containing protein 4, Bromodomain2: BRD4 (BD2) and acetylated histone H4 peptide (H4 K5Ac) using a homogeneous AlphaLISA assay (no wash steps). The assay allows screening of BRD4 inhibitors with a highly-specific substrate.
Price Range : 490.00 GBP - 2610.00 GBP
AlphaPlex-545-antibody-bead2

Anti-Mouse IgG AlphaPlex-545 (Tb) Acceptor Beads

AlphaPlex-545 (Terbium) Acceptor beads conjugated to anti-mouse IgG antibody, for use in Alpha no-wash multiplexing assays.
Price Range : 369.00 GBP - 15130.00 GBP

Anti-c-myc AlphaLISA® Acceptor Beads

AlphaLISA® Acceptor beads conjugated to anti-c-myc antibody. These beads can be used to capture c-myc-tagged proteins and peptides in AlphaLISA no-wash assays.
Price Range : 369.00 GBP - 15140.00 GBP

Anti-mouse IgG (Fc specific) AlphaLISA Acceptor Beads

AlphaLISA® Acceptor beads conjugated to anti-mouse IgG antibody. These beads can be used to capture mouse IgG antibodies. The antibody is Fc-specific, and is a goat polyclonal F(ab')2 fragment.
Price Range : 369.00 GBP - 15140.00 GBP

DELFIA® Eu-N1 Anti-GST

Europium-labeled anti-GST antibody, for capturing GST-tagged proteins in DELFIA® TRF assays.
Price Range : 158.00 GBP - 1940.00 GBP

Anti-DIG AlphaLISA Acceptor Beads

AlphaLISA® Acceptor beads conjugated to a mouse monoclonal anti-Dig (digoxin) antibody. These beads can be used to capture Dig-labeled proteins, peptides, and other biomolecules to create AlphaLISA no-wash assays.
Price Range : 369.00 GBP - 15140.00 GBP
PerkinElmer

SureLight Allophycocyanin-streptavidin (APC-SA), protein binding assay, Iyophilized

APC-labeled streptavidin, for use in LANCE® TR-FRET protein binding assays.
Price Range : 237.00 GBP - 6680.00 GBP
PerkinElmer

LANCE Eu-anti-C-tag antibody

Europium-labeled anti-C-tag antibodies for LANCE® TR-FRET assays. This mouse monoclonal IgG1 antibody recognizes N-terminal and C-terminal Protein C tagged fusion proteins. The anti-C-tag antibody can be used to capture C-tag proteins, and can be used in conjunction with LANCE ULight or SureLight™ APC-labeled reagents to create LANCE TR-FRET assays.
Price Range : 200.00 GBP - 5650.00 GBP

Anti-V5 AlphaLISA Acceptor beads

AlphaLISA® Acceptor beads conjugated to anti-V5 antibody. The mouse monoclonal antibody detects proteins tagged with the V5 14-amino-acid tag (the 9-amino-acid tag has also been successfully bound by the antibody). 
Price Range : 369.00 GBP - 15140.00 GBP

EGF-EGFR LANCE Ultra TR-FRET Binding Kit

This kit is designed for the detection of binding activity between Human EGF and EGFR using a homogeneous LANCE Ultra TR-FRET assay. This assay can facilitate the design and development of therapeutics which competitively inhibit EGF/EGFR interaction.
Price Range : 485.00 GBP - 6460.00 GBP

ULight-anti-V5 (LANCE TR-FRET)

Anti-V5 tag antibody labeled with ULight™ dye. This ULight-labeled reagent can be used to capture V5-tagged proteins and peptides, and can be used in conjunction with LANCE® Europium-labeled reagents to create TR-FRET no-wash assays for protein-protein interaction, protein detection, and enzymatic studies.
Price Range : 261.00 GBP - 6590.00 GBP

Anti-rat IgG (Fc specific) AlphaLISA® Acceptor Beads

AlphaLISA® Acceptor beads conjugated to anti-rat IgG antibody. These beads can be used to capture rat IgG antibodies. The antibody is Fc-specific, and is a goat polyclonal F(ab')2 fragment.
Price Range : 369.00 GBP - 15140.00 GBP

DELFIA Eu-N1 Streptavidin

DELFIA® Europium-labeled streptavidin, for use in DELFIA time-resolved fluorescence (TRF) assays.
List Price : 227.00 GBP

Anti-Maltose-Binding Protein (MBP) AlphaLISA® Acceptor beads

AlphaLISA® Acceptor beads conjugated to anti-MBP (maltose-binding protein) antibody. The antibody is a rat monoclonal antibody, clone MBP 7G4. These beads can be used to capture MBP-tagged proteins for AlphaLISA no-wash assays.
Price Range : 369.00 GBP - 15140.00 GBP

LANCE Ultra ULight™-anti-GST

Goat polyclonal anti-GST tag antibody labeled with ULight™ dye.
Price Range : 263.00 GBP - 6670.00 GBP

AlphaLISA anti-mouse IgG Acceptor beads

AlphaLISA Acceptor beads conjugated to anti-mouse IgG antibody. This antibody is not Fc-specific; for Fc-specific beads, please see product AL105.
Price Range : 354.00 GBP - 14540.00 GBP

Anti-GFP AlphaLISA® Acceptor beads

AlphaLISA® Acceptor beads conjugated to anti-GFP antibody. The antibody is a mouse monoclonal antibody that recognizes wildtype and recombinant GFP (rGFP), and cross-reacts with eGFP. These beads can be used to capture GFP-tagged proteins for AlphaLISA no-wash assays.
Price Range : 369.00 GBP - 15140.00 GBP

"Protein-protein Interaction" 1-50 of 133 Products and Services

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