PerkinElmer

Receptor Ligand Binding

OF

A receptor ligand binding assay allows for the study and simple imaging of cell surface receptors for research and diagnostic applications. Receptor ligand binding is used in drug development applications to identify blocking antibodies or inhibitors that can modulate downstream signaling events, and is often used to screen for drugs that target hormone and neurotransmitter activity. We offer a range of tools for receptor ligand binding assays including radioligands, receptor-transfected cell membranes, and cell lines. Products available support both agonist and antagonist assays.

Our offerings include assays for:

  • Tyrosine kinase receptors
  • G-protein coupled receptors (GPCR)
  • Drug discovery and development
  • Ion channels
  • Protein analysis, detection, and interaction

Our collection of receptor ligand binding related assays includes fluorescence, LANCE® and DELFIA® time-resolved fluorescence, Alpha chemiluminescent assays, lites luminescence assays, and radiometric detection methods. Simplify the development of your assays and the calculation of your results using our radioligands, receptor-transfected cell membranes, and cell lines for receptor ligand binding applications.

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Assay points(200-50,000)
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Concentration
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  • 1.0 mCi/mL (1)
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Detection Method
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Radionuclide
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Radioisotope
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Receptor Type
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"Receptor Ligand Binding" 1-50 of 547 Products and Services

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MICROBETA FILTERMAT-24 CELL HARVESTER

Speed and simplicity are the primary strengths of the FilterMate Harvester. From beginning to end, the FilterMate system is easy to use. Need additional information? Click on the tabs in the product details section below.

UNIFILTER-24 CELL HARVESTER

Speed and simplicity are the primary strengths of the Unifilter Harvester.
LabChip EZ Reader

EZ READER, SHIP LEVEL

The EZ Reader can help to save time and money in your laboratory by identifying the most promising lead candidates faster.

The EZ Reader instrument is available outside the EU. Please contact your local representative for further information.

UNIFILTER-96 CELL HARVESTER SS

Speed and simplicity are the primary strengths of the Unifilter Harvester.

UNIFILTER-96 CELL HARVESTER

Speed and simplicity are the primary strengths of the Unifilter Harvester.

MICROBETA FILTERMAT-96 CELL HARVESTER

Speed and simplicity are the primary strengths of the FilterMate Harvester. From beginning to end, the FilterMate system is easy to use.

OMNIFILTER-96 CELL HARVESTER

Speed and simplicity are the primary strengths of the OmniFilter Harvester.

NAAG, [Glutamate-3,4-3H]

NAAG radioligand tritiated at the 3,4 position. NAAG is a peptide neurotransmitter that activates the metabotropic glutamate receptor type 3.
Price Range : 1040.00 GBP - 2260.00 GBP
PerkinElmer

Membrane Target Systems: Adenosine A1 (human) membrane preparation, in CHO-K1 cells. 400 Units.

Our Membrane Target System membranes are prepared from cells that express recombinant or endogenous receptors. Selected for optimal performance in binding assays.
List Price : 569.00 GBP

Ornithine Vasotocin Analog, [125I]-OVTA)

Ornithine Vasotocin Analog (OVTA), labeled with 125I. OVTA binds oxytocin receptors, a hormone receptor involved in pregnancy, milk production, stress, social memory, and bonding.
Price Range : 1120.00 GBP - 2260.00 GBP
PerkinElmer

Membrane Target Systems: Chemokine XCR1 (human) membrane preparation, in CHO-K1 cells. 400 Units.

Our Membrane Target System membranes are prepared from cells that express recombinant or endogenous receptors. Selected for optimal performance in binding assays.
List Price : 569.00 GBP
PerkinElmer

Membrane Target Systems: Thromboxane TP (human) membrane preparation

Cell membranes prepared from cells stably-transfected with human Thromboxane TP receptor, in HEK-293 cells.
List Price : 569.00 GBP
PerkinElmer

Membrane Target Systems: Vasopressin V1b (human) membrane preparation, in CHO-K1 cells. 400 Units.

Cell membranes prepared from CHO-K1 cells stably-transfected with human Vasopressin V1b receptor, 400 units.
List Price : 569.00 GBP
PerkinElmer

Membrane Target Systems: Adenosine A3 (human) membrane preparation, in CHO-K1 cells. 400 Units.

Our Membrane Target System membranes are prepared from cells that express recombinant or endogenous receptors. Selected for optimal performance in binding assays.
List Price : 488.00 GBP
PerkinElmer

Streptavidin PVT 150MG

Streptavidin-coated SPA beads, for capturing biotinylated biomolecules in proximity-based radiometric scintillation assays.
List Price : 511.00 GBP
Receptor-expressing cell lines

ValiScreen Somatostatin sst3 (human) cell line

Our stable recombinant ValiScreen cell lines express a variety of GPCRs for binding and functional assays.

Apamin [125I]His18-NH2

Apamin, labeled with 125I on histidine residue 18. Apamin is a neurotoxin that acts as an antagonist at calcium-activated potassium channels (SK channels).
Price Range : 925.00 GBP - 1540.00 GBP

RX 821002, [6,7-3H(N)]-

RX 821002, tritiated at the 6,7 position. RX 821002 acts as an antagonist at α2-adrenoceptors.
List Price : 1640.00 GBP
PerkinElmer

Membrane Target Systems: Muscarinic M4 (human) membrane preparation

Cell membranes prepared from cells stably-transfected with human Muscarinic M4 receptor, in CHO-K1 cells.
List Price : 569.00 GBP

MCP-1,[125I]- labeled, Bolton-Hunter Labeled

Monocyte chemoattractant protein 1 (MCP-1; CCL2), labeled with 125I. MCP-1 is a cytokine released by tumor cells that binds chemokine receptor 2 (CCR2).
Price Range : 745.00 GBP - 1760.00 GBP
PerkinElmer

Streptavidin PVT 2G

Streptavidin-coated SPA beads, for capturing biotinylated biomolecules in proximity-based radiometric scintillation assays.
List Price : 6680.00 GBP

Endothelin-1 (human, porcine), [125I]Tyr13

Endothelin-1 (ET-1), labeled with 125I on the tyrosine 13 residue. Endoethlin-1 is a vasoconstrictor that acts as an endogenous agonist at endothelin receptors. Endothelin receptors are a class of GPCRs that are potential drug targets for hypertension and cancer.
Price Range : 926.00 GBP - 2550.00 GBP
PerkinElmer

Serotonin Transporter (human) Cell Line

Our stable recombinant cell lines express a variety of receptors for binding and functional assays.
List Price : 10930.00 GBP

Paroxetine, [Phenyl-6'-3H]

Paroxetine (Paxil), tritiated at the phenyl-6' position. Paroxetine is a selective serotonin reuptake inhibitor (SSRI). This product has a scheduled lot release for the first Monday in May and November.
Price Range : 496.00 GBP - 2210.00 GBP
PerkinElmer

Membrane Target Systems: Neurokinin NK1 (human endogenous) membrane preparation, in UC11 cells. 400 Units.

Cell membranes prepared from UC11 cells with human neurokinin NK1 receptor, 400 units.
List Price : 569.00 GBP
PerkinElmer

Membrane Target Systems: Muscarinic M1 (human) membrane preparation

Cell membranes prepared from cells stably-transfected with human Muscarinic M1 receptor, in CHO-K1 cells.
List Price : 569.00 GBP

Kainic acid, [Isopropenyl-3H]

Kainic acid, tritiated on the isoproprenyl group. Kainic acid acts as an agonist at kainate glutamate receptors.
Price Range : 454.00 GBP - 4200.00 GBP
PerkinElmer

Membrane Target Systems: Transporter Dopamine (human) membrane preparation

Cell membranes prepared from cells stably-transfected with Transporter Dopamine receptor, in CHO-K1 cells.
List Price : 569.00 GBP
PerkinElmer

Membrane Target Systems: Opioid Mu (OP3) (human) membrane preparation, in CHO-K1 cells. 400 Units.

Our Membrane Target System membranes are prepared from cells that express recombinant or endogenous receptors. Selected for optimal performance in binding assays.
List Price : 569.00 GBP
PerkinElmer

Streptavidin PS Imaging Beads 50 MG

Streptavidin-coated SPA beads, for capturing biotinylated molecules in proximity-based scintillation assays.
List Price : 89.00 GBP

RTI-55, [125I]

RTI-55, labeled with 125I. RTI-55 is a nonselective dopamine reuptake inhibitor that is used to assess neuron degradation in Parkinson's disease and other neurodegenerative diseases.
Price Range : 918.00 GBP - 1830.00 GBP
PerkinElmer

WGA-PEI TYPE A PS 50 MG

WGA-coated SPA beads, for capturing cell membranes in proximity-based scintillation assays.
List Price : 26.00 GBP
Receptor-expressing cell lines

ValiScreen Chemokine XCR1 (human) cell line

Our stable recombinant ValiScreen cell lines express a variety of GPCRs for binding and functional assays.

TCP, [Piperdyl-3,4-3H(N)]

Tenocyclidine (TCP), tritiated at the piperdyl-3,4 position. TCP acts as an antagonist at N-methyl-D-aspartate receptor (NMDA receptors).
Price Range : 518.00 GBP - 1890.00 GBP
PerkinElmer

Streptavidin PVT 500MG

Streptavidin-coated SPA beads, for capturing biotinylated biomolecules in proximity-based radiometric scintillation assays.
List Price : 1670.00 GBP
Receptor-expressing cell lines

ValiScreen Somatostatin sst5 (human) cell line

Our stable recombinant ValiScreen cell lines express a variety of GPCRs for binding and functional assays.
PerkinElmer

Membrane Target Systems: Serotonin 5HT7 (human) membrane preparation, in CHO-K1 cells. 400 Units.

Cell membranes prepared from CHO-K1 cells stably-transfected with human serotonin 5HT7 receptor, 400 units.
List Price : 569.00 GBP

Insulin-like Growth Factor-I (human, recombinant), 125I

Insulin-like growth factor 1 (IGF-1), labeled with 125I. IGF-1 acts as an agonist at the IGF-1 receptor, a receptor tyrosine kinase, that plays a role in growth, cancer, and aging. IGF-1 also binds the insulin receptor (IR), another receptor tyrosine kinase involved in glucose homeostasis, diabetes, and cancer.
Price Range : 685.00 GBP - 1680.00 GBP
PerkinElmer

Membrane Target Systems: Serotonin 5HT5a (human) membrane preparation

Cell membranes prepared from cells stably-transfected with human Serotonin 5-HT5a receptor, in HEK-293 cells.
List Price : 569.00 GBP
PerkinElmer

ProfilerPro Kinase Selectivity Assay Plate Kit 9, for LabChip EZ Reader

Kit consist of matched pairs of 384-well kinase-assay and substrate plates. Each assay plate contains 24 different predispensed frozen kinases. Substrate plates contain the appropriate fluorescent labeled peptides and ATP.
List Price : 985.00 GBP

Neurokinin B, [125I]His, MePhe7

Neurokinin B (NKB), labeled with 125I on the histidine residue. Neurokinin B is involved in ovarian cycle regulation, and binds neurokinin 3 receptor (NK3R; tachykinin receptor 3), a GPCR involved in vascular remodeling, angiogenesis, and cancer.
Price Range : 995.00 GBP - 2320.00 GBP

Somatostatin, [125I]Tyr11

Somatostatin, labeled with 125I. Somatostatin binds somatostatin receptors, and inhibits the secretion of insulin and glucagon.
Price Range : 918.00 GBP - 2140.00 GBP

Prazosin, [7-Methoxy-3H]

Prazosin, tritiated at the 7-methoxy position. Prazosin acts as an inverse agonist at the α1-adrenergic receptor.
Price Range : 558.00 GBP - 4410.00 GBP

CGRP (human), [125I]

Calcitonin gene-related peptide (CGRP), labeled with 125I. CGRP binds calcitonin receptors.
Price Range : 809.00 GBP - 1960.00 GBP
PerkinElmer

Membrane Target Systems: Adenosine A1 (rat) membrane preparation, in CHO-K1 cells. 400 Units.

Cell membranes prepared from CHO-K1 cells stably-transfected with rat adenosine A1 receptor, 400 units.
List Price : 569.00 GBP

[125I]- Epidermal Growth Factor (human, rat)

NEX428 Epidermal Growth Factor is radioiodinated with no carrier added 125I using a lactoperoxidase procedure and is purified by reversed phase HPLC.
Price Range : 736.00 GBP - 1620.00 GBP
Receptor-expressing cell lines

ValiScreen Calcitonin CGRP1 (human) cell line

Our stable recombinant ValiScreen cell lines express a variety of GPCRs for binding and functional assays.

WIN 35428, [N-Methyl-3H]

WIN 35428 [(–)-2-β-Carbomethoxy-3-β-(4-fluorophenyl)tropane], tritiated on the N-methyl group. WIN 35428 acts as an antagonist at dopamine transporters (DATs).
Price Range : 564.00 GBP - 4040.00 GBP
PerkinElmer

Membrane Target Systems: Muscarinic M2 (human) membrane preparation

Cell membranes prepared from cells stably-transfected with human Muscarinic M2 receptor, in CHO-K1 cells.
List Price : 569.00 GBP
PerkinElmer

CHO cell membranes, 10 mg

Wild Type Subtype CHO-K1 (chinese hamster) Control Membrane 10mg frozen suspension cell membrane. Shipped on dry ice.
List Price : 339.00 GBP

"Receptor Ligand Binding" 1-50 of 547 Products and Services

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