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CITRIC ACID, [1,5-14C]-

50 µCi quantities of [14C]-Citric acid are available for your research.

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Unit Size
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NEC160050UC
50 µCi
603.00 GBP
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NEC160250UC
50 µCi
2160.00 GBP
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Detail Information

ATP citrate lyase (ACL) is a cytosolic enzyme that catalyzes the synthesis of acetyl-CoA and oxaloacetate using citrate, CoA, and ATP as substrates and Mg2+ as a necessary cofactor. The ACL-dependent synthesis of acetyl-CoA is thought to be an essential step for the de novo synthesis of fatty acids and cholesterol. For this reason, inhibition of ACL has been pursued as a strategy to treat dyslipidemia and obesity.

Specifications

Concentration 0.05 mCi/mL
Detection Method Radiometric
Label Position Specifically Labeled
Molecular Weight 192.12
Product Brand Name NEN Radiochemicals
Radioisotope C-14
Radionuclide 14C
Shipping Condition Blue Ice
Special Ordering Information This is a radioactive product - shipping address must have a license to receive radioactive materials.
Unit Size 50 µCi