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TGF-β1 (human, recombinant), [125I], 10µCi

Transforming growth factor beta 1 (TGF-β1), labeled with 125I. TGF-β1 is a cytokine that is involved in cell growth, cell differentiation, and apoptosis.

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Unit Size
List Price
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NEX267005UC
5 µCi
858.00 GBP
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NEX267010UC
10 µCi
1030.00 GBP
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NEX267025UC
25 µCi
2150.00 GBP
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Detail Information

We offer radioligands and radiolabeled biomolecules to use as tracers, for radioimmunoassays (RIAs), for autoradiographic visualization, or for performing saturation and competition radioligand binding assays to determine receptor expression levels (Bmax), dissociation constants (Kd), association and dissociation rates (kon and koff), and inhibitor constants (Ki) for a variety of receptors. We develop our radioligands to the highest specific activity possible and provide high purity resulting in low non-specific binding products. Each of our ultra-pure radiolabeled compounds is fully characterized for pharmacological action and validated in binding assays.

Radiochemicals remain the most sensitive method for probing binding biology; yielding unprecedented sensitivity gives results that technicians and scientists can trust. For over 50 years, PerkinElmer has been a leading supplier of New England Nuclear (NEN) radiochemicals, liquid scintillation cocktails, vials and nuclear counting detection instruments.

References for NEX267:

  1. Hajnická, V., Vančová-Štibrániová, I., Slovák, M., Kocáková, P., Nuttall, P.A. (2011), Ixodid tick salivary gland products target host wound healing growth factors. Int J Parasitol, 41 (2): 213-232.
  2. Tang, Q., Staub, C.M., Gao, G., Jin, Q., Wang, Z., Ding, W., Aurigemma, R.E., Mulder, K.M. (2002), A novel transforming growth factor-beta receptor-interacting protein that is also a light chain of the motor protein dynein. Mol Biol Cell, 13 (12): 4484-4496.

Specifications

Concentration 41.4 µCi/mL
Detection Method Radiometric
Fresh Lot Days Fourth Monday of each month
Label Position Nominally Labeled
Product Brand Name NEN Radiolabeled Ligands
Radioisotope I-125
Radionuclide 125I
Receptor Type Transforming Growth Factor
Shipping Condition Dry Ice
Special Ordering Information This is a radioactive product - shipping address must have a license to receive radioactive materials.
Therapeutic Area CNS & Neurologic, Cardiovascular, Inflammation, Diabetes, Cancer
Unit Size 10 µCi