PerkinElmer

CNS Research

OF

CNS research seeks to advance treatment for central nervous system disorders through the discovery and quantitation of biomarkers, mechanisms, and drug targets. Our broad range of CNS products meets all the needs of in vitro, in situ, and in vivo central nervous system research.

We offer biomarker detection kits with AlphaLISA® and LANCE® TR-FRET technology, cellular and in vivo imaging systems, and tissue pathology solutions to assess mechanisms of CNS disease in biochemical, cellular, tissue, and animal models. We also provide target-specific radiochemicals, radioligands, and receptor-transfected cell lines and cell membranes.

Applications for our CNS products include:

  • Measuring biomarkers of CNS disease in cells, brain tissue homogenates, cerebrospinal fluid, and other sample types with our fast, pre-validated kits
  • Studying targeted binding using our radiolabeled ligands and steroids
  • Quantitating biomarkers in tissue samples with our industry-leading immunohistochemistry products
  • CNS research in animal models from molecular, functional, and anatomical perspectives with our in vivo imaging systems
  • Performing phenotypic analysis with our high content screening solutions

Our CNS products are also well suited for CNS research in neurodegenerative diseases such as Alzheimer’s, Parkinson’s, and Huntington’s. Gain precise insight on disease biomarkers like phospho-tau, Ab42/Ab40, vimentin, and frataxin, as well as relevant receptors such as dopamine DA1R/DA2R.

  • Products & Services

  • Resources, Events & More

Narrow your results
Product Type
  • Accessories (34)
  • Consumables (2)
  • Reagents (150)
  • Software and Informatics (6)
Assay Target
  • Aβ1-40 (3)
  • Aβ1-42 (2)
  • Aβ1-x (1)
  • Aβ40 (3)
  • Aβ42 (1)
  • BDNF (2)
  • EPO (1)
  • Frataxin (2)
  • GAD67 (2)
  • pNFH (1)
  • Tau (1)
  • TDP-43 (2)
Target Species
  • Human (18)
  • Mouse (2)
Application
  • cAMP (11)
  • Drug Discovery & Development (46)
  • Immunohistochemistry (IHC) (23)
  • In situ hybridization (ISH) (23)
  • Molecular Biology (2)
  • Protein Analysis & Detection (20)
Therapeutic Area
  • Angiogenesis (9)
  • Cardiovascular (37)
  • Central Nervous System (91)
  • CNS & Neurologic (1)
  • Diabetes (10)
  • Gastrointestinal (31)
  • Inflammation (51)
  • Metabolic (30)
  • Obesity (1)
  • Pain (21)
Product Brand Name
  • AequoScreen (14)
  • AequoZen (12)
  • AlphaLISA (11)
  • Ancillary Products (2)
  • cAMPZen (7)
  • LANCE Ultra (10)
  • Membrane Target Systems (35)
  • NEN (2)
  • NEN Radiochemicals (1)
  • Operetta (29)
  • Operetta CLS AND Opera Phenix (7)
  • TSA (12)
  • TSA Plus (12)
  • ValiScreen (15)
Detection Method
  • Alpha (11)
  • Chromogenic (6)
  • Fluorescence (25)
  • Radiometric (3)
  • Time-Resolved Fluorescence (TRF) (10)
  • TR-FRET (10)
Receptor Type
  • 5-Hydroxytryptamine (Serotonin) (38)
  • Adrenergic (10)
  • Cannabinoid (9)
  • Dopamine (8)
  • GABA (4)
  • Galanin (10)
  • Neurotensin (4)
  • Nicotinic (4)
  • Opioid (11)
  • Tachykinin (1)
Assay Validated
  • Binding (72)
  • Calcium Fluorescence (16)
  • Calcium Luminescence (32)
  • cAMP (20)
  • Downstream Phosphorylation (5)
  • GTPγS (19)
  • Inositol Phosphate (3)
Radioisotope
  • H-3 (1)
  • S-35 (2)
Radionuclide
  • 35S (2)
  • 3H (1)
Volume Capacity
  • 150 µL (2)
Nucleotide
  • UTP (2)
Fluorophore
  • Coumarin (1)
  • Cy3 (8)
  • Cy5 (4)
  • Fluorescein (6)
  • TMR (5)
Label Position
  • alpha (2)
  • Nominally Labeled (1)
Buffer
  • Tricine (2)
Assay points(200-50,000)
  • 100 (1)
  • 10000 (5)
  • 500 (15)
  • 5000 (10)
Assay Target Class
  • Cytokine (1)
  • GPCR (80)
  • Ion channel (3)
  • Peptide (9)
  • Protein (11)
Automation Compatible
  • Yes (21)
Concentration
  • 12.5 mCi/mL (1)
Experimental Type
  • In vitro (20)
Format
  • Microplates (20)
  • Slides (23)
Host Cell
  • 1321N1 (4)
  • CHO-K1 (65)
  • HEK293 (13)
  • L Cells (1)
  • UC11 (1)
Model Compatible With
  • Operetta (29)
  • Operetta CLS AND Opera Phenix (7)
Pipetting Arms
Volume
  • 0-50 (1)

"CNS Research" 1-50 of 192 Products & Services

Sort
Per Page
Receptor-expressing cell lines

Serotonin 5-HT6 AequoScreen; cell line

Our stable recombinant AequoScreen cell lines express a variety of GPCRs which all couple to a calcium response. Upon GPCR stimulation and subsequent calcium binding to the aequorin oxidation of coelenterazine leads to emission of light.
Receptor-expressing cell lines

AequoZen FroZen cells, Serotonin 5-HT6, Human Recombinant, CHO-K1

Our frozen, irradiated AequoZen cells express a variety of GPCRs which all couple to a calcium response. Upon GPCR stimulation and subsequent calcium binding to the aequorin oxidation of coelenterazine leads to emission of light. No cell culture is required prior to testing, for these frozen cells.
List Price : 621.00 GBP
Amplification Diluent

TSA Tetramethylrhodamine Tyramide Reagent Pack, Reagents for 100-300 Slides

TSA® tetramethylrhodamine (TMR) reagent pack, for amplification of signal in immunohistochemistry (IHC), immunofluorescence (IF) or in situ hybridization protocols. These reagents amplify by depositing extra biotin in the localized area of the probe or antibody.
List Price : 394.00 GBP
PerkinElmer

Membrane Target Systems: Serotonin 5HT-2A (human) membrane preparation, in CHO-K1 cells. 400 Units.

Our Membrane Target System membranes are prepared from cells that express recombinant or endogenous receptors. Selected for optimal performance in binding assays.
List Price : 597.00 GBP
Amplification Diluent

TSA Fluorescein Reagent Pack

TSA® fluorescein reagent pack, for amplification of signal in immunohistochemistry (IHC), immunofluorescence (IF) or in situ hybridization protocols. These reagents amplify by depositing extra biotin in the localized area of the probe or antibody.
Price Range : 394.00 GBP - 1850.00 GBP
Receptor-expressing cell lines

AequoZen Frozen cells, Serotonin 5-HT2C (edited isoform), Human Recombinant, CHO-K1

Our frozen, irradiated AequoZen cells express a variety of GPCRs which all couple to a calcium response. Upon GPCR stimulation and subsequent calcium binding to the aequorin oxidation of coelenterazine leads to emission of light. No cell culture is required prior to testing, for these frozen cells.
List Price : 621.00 GBP

pNFH (human) AlphaLISA Detection Kit

The AlphaLISA® immunoassay kit for human phosphorylated neurofilament heavy chain protein (pNFH) enables the quantitative determination of human pNFH in plasma or cerebrospinal fluid (CSF) using a homogeneous AlphaLISA assay (no wash steps).
Price Range : 494.00 GBP - 7290.00 GBP
Receptor-expressing cell lines

Opioid Mu (OP3) (human) ValiScreen cell line

Our stable recombinant ValiScreen cell lines express a variety of GPCRs for binding and functional assays.
AlphaLisa Analyte 2

Aβ 1-40 (human), lyophilized (AlphaLISA)

Human Aβ 1-40 standard, lyophilized, for use in running standard curves in AlphaLISA no-wash immunoassays. This standard is already provided in the AlphaLISA Human Aβ 1-40 Detection Kit, but can be ordered separately.
List Price : 165.00 GBP
Receptor-expressing cell lines

Serotonin 5-HT2C (ne) AequoScreen cell line

Our stable recombinant AequoScreen cell lines express a variety of GPCRs which all couple to a calcium response. Upon GPCR stimulation and subsequent calcium binding to the aequorin oxidation of coelenterazine leads to emission of light.
TSA Biotin System

TSA Biotin System

TSA® biotin detection kit, for amplification of signal in immunohistochemistry (IHC), immunofluorescence (IF) or in situ hybridization protocols. This kit amplifies by depositing extra biotin in the localized area of the probe or antibody.
Price Range : 261.00 GBP - 870.00 GBP
PerkinElmer

Membrane Target Systems: Neurokinin NK1 (human endogenous) membrane preparation, in UC11 cells. 400 Units.

Cell membranes prepared from UC11 cells with human neurokinin NK1 receptor, 400 units.
List Price : 597.00 GBP
AlphaLISA immunoassay kits

Amyloid β 1-42 (human) AlphaLISA Detection Kit

The AlphaLISA® immunoassay kit for detection and quantitation of human Amyloid β 1-40 (Aβ 1-40) in cerebrospinal fluid (CSF), cell culture supernatants, and other sample types allows for fast, reproducible, and sensitive detection without the need for time-consuming wash steps or complicated assay development.
Price Range : 2000.00 GBP - 15630.00 GBP
Receptor-expressing cell lines

AequoZen FroZen cells, Adrenergic α2A, Human Recombinant, CHO-K1

Our frozen, irradiated AequoZen cell lines express a variety of GPCRs which all couple to a calcium response. Upon GPCR stimulation and subsequent calcium binding to the aequorin oxidation of coelenterazine leads to emission of light. No cell culture is required prior to testing, for these frozen cells.
List Price : 621.00 GBP
AlphaLISA immunoassay kits

Amyloid β 1-42 (high specificity) (human) AlphaLISA Detection Kit

The AlphaLISA® Human Amyloid beta 1-42 (Aß 1-42) (high specificity) Detection Kit is designed for detection and quantitation of human Aß 1-42 in cerebrospinal fluid (CSF), buffered solution or cell culture medium in a homogeneous (no-wash steps, no separation steps) assay.
Price Range : 2000.00 GBP - 15630.00 GBP
Protein

Frataxin (human), lyophilized (LANCE)

Human Frataxin standard, lyophilized, for use in running standard curves in LANCE TR-FRET no-wash detection assays. This standard is already provided in the LANCE Ultra Human Frataxin TR-FRET Detection Kit, but can be ordered separately.
List Price : 165.00 GBP
PerkinElmer

Anti-DNP AP Conjugate

Anti-DNP antibody conjugated to alkaline phosphatase
List Price : 293.00 GBP
PerkinElmer

TSA Fluorescein System

TSA® fluorescein detection kit, for amplification of signal in immunohistochemistry (IHC), immunofluorescence (IF) or in situ hybridization protocols. This kit amplifies by depositing extra fluorescein in the localized area of the probe or antibody.
Price Range : 335.00 GBP - 588.00 GBP
TSA Plus DNP (HRP)System

TSA Plus DNP (HRP)

TSA® Plus DNP (HRP) detection kit, for amplification of signal in immunohistochemistry (IHC), immunofluorescence (IF) or in situ hybridization protocols. The deposited DNP is detected using an anti-DNP hroseradish peroxidase, with appropriate substrate.
Price Range : 175.00 GBP - 311.00 GBP
AlphaLISA immunoassay kits

Aβ 1-40 (human) High Specificity AlphaLISA Detection Kit

The AlphaLISA® immunoassay kit for human Aβ40 enables the detection and quantitation of human Aβ40 in human cerebrospinal fluid and cell culture supernatants using a homogeneous AlphaLISA assay (no wash steps). The assay shows negligible cross-reactivity with other forms of Amyloid beta (i.e. Aβ1-38 and Aβ1-42).
Price Range : 1940.00 GBP - 15150.00 GBP

Aβ(1-40) (human) High Specificity LANCE Ultra TR-FRET Detection Kit

The LANCE® Ultra Human Aβ(1-40) High Specificity Detection Kit is designed for detection and quantitation of human Aβ(1-40) in cell culture media using a homogeneous TR-FRET (no-wash steps, no separation steps) assay.
Price Range : 547.00 GBP - 7290.00 GBP
Receptor-expressing cell lines

AequoZen FroZen cells, Serotonin 5-HT3A, Human Recombinant, HEK293

Our frozen, irradiated AequoZen cells express a variety of GPCRs which all couple to a calcium response. Upon GPCR stimulation and subsequent calcium binding to the aequorin oxidation of coelenterazine leads to emission of light. No cell culture is required prior to testing, for these frozen cells.
List Price : 621.00 GBP
PerkinElmer

Membrane Target Systems: Dopamine D1 (human) membrane preparation, in L cells cells. 400 Units.

Cell membranes prepared from L cells stably-transfected with human dopamine D1 receptor, 400 units.
List Price : 597.00 GBP
Receptor-expressing cell lines

AequoZen Frozen cells, Serotonin 5-HT2A, Human Recombinant, CHO-K1

Our frozen, irradiated AequoZen cells express a variety of GPCRs which all couple to a calcium response. Upon GPCR stimulation and subsequent calcium binding to the aequorin oxidation of coelenterazine leads to emission of light. No cell culture is required prior to testing, for these frozen cells.
List Price : 621.00 GBP
PerkinElmer

TSA Plus DIG Evaluation Kit

TSA® Plus DIG detection kit, for amplification of signal in immunohistochemistry (IHC), immunofluorescence (IF) or in situ hybridization protocols. This kit amplifies by depositing extra DIG in the localized area of the probe or antibody.
Price Range : 147.00 GBP - 972.00 GBP
Receptor-expressing cell lines

AequoZen FroZen cells, Opioid mu, Human Recombinant, CHO-K1

Our frozen, irradiated AequoZen cells express a variety of GPCRs which all couple to a calcium response. Upon GPCR stimulation and subsequent calcium binding to the aequorin oxidation of coelenterazine leads to emission of light. No cell culture is required prior to testing, for these frozen cells.
List Price : 621.00 GBP
Receptor-expressing cell lines

Opioid Mu (OP3), Human Recombinant, CHO-K1 cAMPZen Frozen cells

Our frozen, irradiated cAMPZen cells express a variety of GPCRs for binding and functional assays. No cell culture is required prior to testing.
List Price : 391.00 GBP
Receptor-expressing cell lines

ValiScreen Adrenergic alpha 2A (human) cell line

Our stable recombinant ValiScreen cell lines express a variety of GPCRs for binding and functional assays.
Receptor-expressing cell lines

Dopamine D1 (human) ValiScreen® cell line

Our stable recombinant ValiScreen cell lines express a variety of GPCRs for binding and functional assays.
AlphaLISA immunoassay kits

Amyloid ß 1-x (human) AlphaLISA Detection Kit

The AlphaLISA® Human Amyloid beta 1-x (Aß 1-x) Detection Kit is designed for detection and quantitation of human Aß 1-x in cerebrospinal fluid (CSF), buffered solution or cell culture medium in a homogeneous (no-wash steps, no separation steps) assay.
Price Range : 2000.00 GBP - 15630.00 GBP
Receptor-expressing cell lines

AequoZen Frozen cells, Serotonin 5-HT2C (non edited isoform), Human Recombinant, CHO-K1

Our frozen, irradiated AequoZen cells express a variety of GPCRs which all couple to a calcium response. Upon GPCR stimulation and subsequent calcium binding to the aequorin oxidation of coelenterazine leads to emission of light. No cell culture is required prior to testing, for these frozen cells.
List Price : 621.00 GBP

BDNF (human) LANCE Ultra TR-FRET Detection Kit

The LANCE® Ultra Human BDNF Detection Kit is designed for detection and quantitation of human BDNF in buffered solution and cell culture media using a homogeneous TR-FRET (no-wash steps, no separation steps) assay.
Price Range : 531.00 GBP - 7070.00 GBP
PerkinElmer

Membrane Target Systems: Opioid Mu (OP3) (human) membrane preparation, in CHO-K1 cells. 400 Units.

Our Membrane Target System membranes are prepared from cells that express recombinant or endogenous receptors. Selected for optimal performance in binding assays.
List Price : 597.00 GBP
PerkinElmer

TSA Plus Fluorescein

TSA® Plus fluorescein detection kit, for amplification of signal in immunohistochemistry (IHC), immunofluorescence (IF) or in situ hybridization protocols. This kit amplifies by depositing extra fluorescein in the localized area of the probe or antibody.
Price Range : 137.00 GBP - 1460.00 GBP
LANCE Detection Kit

Frataxin (human) LANCE Ultra TR-FRET Detection Kit

The LANCE® Ultra Human Frataxin Detection Kit is designed for detection and quantitation of human frataxin in cell culture media using a homogeneous TR-FRET (no-wash steps, no separation steps) assay.
Price Range : 547.00 GBP - 7290.00 GBP
PerkinElmer

Membrane Target Systems: Serotonin 5HT6 (human) membrane preparation

Cell membranes prepared from cells stably-transfected with human Serotonin 5-HT6 receptor, in HEK-293 cells.
List Price : 597.00 GBP
Receptor-expressing cell lines

Serotonin 5-HT1A AequoScreen; cell line

Our stable recombinant AequoScreen cell lines express a variety of GPCRs which all couple to a calcium response. Upon GPCR stimulation and subsequent calcium binding to the aequorin oxidation of coelenterazine leads to emission of light.
PerkinElmer

Membrane Target Systems: Serotonin 5HT-5A (human) membrane preparation, in CHO-K1 cells. 400 Units.

Our Membrane Target System membranes are prepared from cells that express recombinant or endogenous receptors. Selected for optimal performance in binding assays.
List Price : 597.00 GBP
Receptor-expressing cell lines

ValiScreen Nicotinic HM74a (human) cell line

Our stable recombinant ValiScreen cell lines express a variety of GPCRs for binding and functional assays.
Receptor-expressing cell lines

AequoZen FroZen cells, Cannabinoid CB1, Human Recombinant, CHO-K1

Our frozen, irradiated AequoZen cell lines express a variety of GPCRs which all couple to a calcium response. Upon GPCR stimulation and subsequent calcium binding to the aequorin oxidation of coelenterazine leads to emission of light. No cell culture is required prior to testing, for these frozen cells.
List Price : 621.00 GBP
AlphaLISA immunoassay kits

Amyloid β 1-40 (human) AlphLISA Detection Kit

The AlphaLISA® immunoassay kit for detection and quantitation of human Amyloid β 1-40 (Aβ 1-40) in cerebrospinal fluid (CSF), cell culture supernatants, and other sample types allows for fast, reproducible, and sensitive detection without the need for time-consuming wash steps or complicated assay development.
Price Range : 2040.00 GBP - 15630.00 GBP
PerkinElmer

Membrane Target Systems: Serotonin 5HT-2B (human) membrane preparation, in CHO-K1 cells. 400 Units.

Our Membrane Target System membranes are prepared from cells that express recombinant or endogenous receptors. Selected for optimal performance in binding assays.
List Price : 597.00 GBP
Receptor-expressing cell lines

ValiScreen Serotonin 5HT-6 (human) cell line

Our stable recombinant ValiScreen cell lines express a variety of GPCRs for binding and functional assays.
PerkinElmer

Membrane Target Systems: Opioid Delta (human) membrane preparation, in HEK-293 cells. 400 Units.

Cell membranes prepared from HEK293 cells stably-transfected with human opioid delta receptor, 400 units.
List Price : 597.00 GBP
Receptor-expressing cell lines

cAMPZen Frozen cells, Adrenergic α2A, Human Recombinant, CHO-K1

Our frozen, irradiated cAMPZen cells express a variety of GPCRs for binding and functional assays. No cell culture is required prior to testing.
List Price : 391.00 GBP
PerkinElmer

Membrane Target Systems: Nociceptin NOP (ORL1) (human) membrane preparation, in CHO-K1 cells. 400 Units.

Cell membranes prepared from CHO-K1 cells stably-transfected with human Nociceptin NOP (ORL1) receptor, 400 units.
List Price : 597.00 GBP
Receptor-expressing cell lines

AequoZen Frozen cells, Serotonin 5-HT5A Human Recombinant, CHO-K1

Our frozen, irradiated AequoZen cells express a variety of GPCRs which all couple to a calcium response. Upon GPCR stimulation and subsequent calcium binding to the aequorin oxidation of coelenterazine leads to emission of light. No cell culture is required prior to testing, for these frozen cells.
List Price : 621.00 GBP
Receptor-expressing cell lines

AequoZen FroZen cells, Serotonin 5-HT1A, Human Recombinant, CHO-K1

Our frozen, irradiated AequoZen cells express a variety of GPCRs which all couple to a calcium response. Upon GPCR stimulation and subsequent calcium binding to the aequorin oxidation of coelenterazine leads to emission of light. No cell culture is required prior to testing, for these frozen cells.
List Price : 621.00 GBP
TSA Coumarin System (100-300 slides)

TSA Coumarin System, for 100-300 Slides

TSA® coumarin detection kit, for amplification of signal in immunohistochemistry (IHC), immunofluorescence (IF) or in situ hybridization protocols. This kit amplifies by depositing extra coumarin in the localized area of the probe or antibody.
List Price : 588.00 GBP
Receptor-expressing cell lines

AequoZen Frozen cells, Adrenergic α2B, Human Recombinant, CHO-K1

Our frozen, irradiated AequoZen cell lines express a variety of GPCRs which all couple to a calcium response. Upon GPCR stimulation and subsequent calcium binding to the aequorin oxidation of coelenterazine leads to emission of light. No cell culture is required prior to testing, for these frozen cells.
List Price : 621.00 GBP

"CNS Research" 1-50 of 192 Products & Services

Per Page