PerkinElmer

Ligands

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Eliminate the need for antibodies and reduce assay time with direct detection using our radiolabeled ligands, which provide for sensitive and quantitative measurement of binding.

  • High specific activity — The majority of our 125I-labeled ligands are offered at maximum specific activity. This means virtually every molecule of ligand provided in the stock vial is radiolabeled. For tritiated ligands (3H ligands), pick a ligand with specific activity above 20 Ci/mmol – all of our tritiated ligands meets or exceeds these requirements.
  • High purity — We offer highly-pure radioligands for the highest specific signal with low background in binding assays.
  • High selectivity — Our broad portfolio of agonists and antagonists offers many options for choosing the most selective compound for your receptor.
  • Validated for receptor binding — all of our radioligand products are tested for receptor binding during development. Additionally, many of our radioligands are used to QC our GPCR and receptor cell lines and cell membrane products.

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"Ligands" 1-50 of 116 Products & Services

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Adenosine 5 Triphosphate 250 µCi

Propranolol, L-[4-3H]-, 250µCi (9.25MBq)

L-propranolol, tritiated at the 4 position. Propranolol is a non-selective beta blocker that acts as a potent antagonist for β-adrenoceptors.
List Price : 1150.00 GBP
Adenosine 5 Triphosphate 250 µCi

RO 15-4513, [7,9-3H]-, 250µCi (9.25MBq)

Ro15-4513, tritiated at the 7,9 position. Ro15-4513 is a partial inverse agonist at GABAA receptors.
List Price : 2120.00 GBP
Adenosine 5 Triphosphate 250 µCi

Dihydroxyphenylethylamine, 3,4-[7-3H]

Dihydroxyphenylethylamine (dopamine, DA), tritiated at the 7 position. Dihydroxyphenylethylamine is a neurotransmitter and is the primary endogenous ligand for dopamine receptors. This product has a scheduled lot release for the second Monday in April and October.
Price Range : 832.00 GBP - 2340.00 GBP
Adenosine 5 Triphosphate 250 µCi

Dihydroxyphenylethylamine (Dopamine), 3,4-[Ring-2,5,6-3H]

Dihydroxyphenylethylamine (dopamine, DA), tritiated at the ring-2,5,6- position. Dihydroxyphenylethylamine is a neurotransmitter and is the primary endogenous ligand for dopamine receptors.
Price Range : 563.00 GBP - 1370.00 GBP
Adenosine 5 Triphosphate 250 µCi

Quinuclidinyl Benzilate, L-[Benzilic-4,4`-3H]-, 250µCi (9.25MBq)

L-quinuclidinyl benzilate (QNB), tritiated at the benzilic-4,4' position. L-quinuclidinyl benzilate acts as an antagonist at muscarinic acetylcholine receptors.
List Price : 1230.00 GBP
Adenosine 5 Triphosphate 250 µCi

GABAPENTIN [3H]

Tritiated gabapentin (Neurontin). Gabapentin is a medication used to treat epilepsy, and has been shown to cross membrane lipid barriers via system L-amino acid transporters and bind to voltage-gated calcium channels in the central nervous system. This product has a scheduled release for the third Monday in February and September.
List Price : 4680.00 GBP
Adenosine 5 Triphosphate 250 µCi

Raclopride, [Methoxy-3H]

Raclopride, [Methoxy-3H]- will have fresh lot dates on the second Monday in March and September.
Price Range : 491.00 GBP - 3920.00 GBP
Adenosine 5 Triphosphate 250 µCi

Serine, D-[3H(G)]-, 250µCi (9.25MBq)

Tritiated D-Serine. D-Serine acts as an agonist at N-methyl-D-aspartate receptors (NMDA receptors).
List Price : 1740.00 GBP
Adenosine 5 Triphosphate 250 µCi

Vasopressin (8-L-Arginine), [Phenylalanyl-3,4,5-3H(N)]

Vasopressin, tritiated on the phenylalanine residue. Vasopressin binds and activates vasopressin receptors.
Price Range : 580.00 GBP - 2080.00 GBP
Adenosine 5 Triphosphate 250 µCi

Ryanodine, [9,21-3H(N)]-, 250µCi (9.25MBq)

Ryanodine, tritiated at the 9,21 position. Ryanodine is a natural ligand for the ryanodinen receptor.
List Price : 2020.00 GBP
Adenosine 5 Triphosphate 250 µCi

Cyclopentyl-1,3-Dipropylxanthine, 8-[Dipropyl-2,3-3H(N)]

8-Cyclopentyl-1,3-dipropylxanthine (DPCPX, PD-116,948), tritiated at the dipropyl-2,3- positions. DPCPX acts as a potent and selective antagonist for the adenosine A1 receptor.
Price Range : 1140.00 GBP - 2620.00 GBP
Adenosine 5 Triphosphate 250 µCi

(-)-CGP-12177, [5,7-3H]

(-)-CGP-12177 radioligand tritiated at the 5,7 position. CGP-12177 acts as an antagonist at the β1- and β2-adrenoceptors and a partial agonist at β3-adrenoceptors.
Price Range : 450.00 GBP - 1120.00 GBP
Diclofenac sodium- Phenylacetic acid C14

COUMARIN, 7-ETHOXY, [3- 14C]-

50 µCi quantities of 7-ETHOXY-[3-14C]-Coumarin are available for your research.
List Price : 1710.00 GBP
Adenosine 5 Triphosphate 250 µCi

Norepinephrine, Levo-[7-3H]

Levo-Norepinephrine, tritiated at the 7 position. Norepinephrine binds and activates adrenergic receptors, and is cleared by the norepinehprine transporter (NET). This product has a scheduled lot release for the third Monday in July.
Price Range : 1050.00 GBP - 8750.00 GBP
Adenosine 5 Triphosphate 250 µCi

U-69,593, [Phenyl-3,4-3H]

U-69,593, tritiated at the phenyl-3,4 position. U-69,593 is a selective κ1-opioid receptor agonist.
Price Range : 608.00 GBP - 1980.00 GBP
Adenosine 5 Triphosphate 250 µCi

Cytisine HCl, [3,5-3H(N)]

Cytisine HCl, [3,5-3H(N)]- will have fresh lot dates on the second Monday in April.
Price Range : 524.00 GBP - 1880.00 GBP
Adenosine 5 Triphosphate 250 µCi

CGP 39653, [Propyl-2,3,3H]

CGP 39653, tritiated at the propyl-2,3 position. CGP 39653 acts as an N-methyl-D-aspartate (NMDA) antagonist.
Price Range : 562.00 GBP - 4800.00 GBP
Adenosine 5 Triphosphate 250 µCi

8-Hydroxy-DPAT, [Propyl-2,3-ring-1,2,3-3H]-

8-OH-DPAT radioligand tritiated at the 1,2,3 position on the propyl-2,3-ring. 8-OH-DPAT is a serotonin receptor agonist specific for the 5-HT1A and 5-HT7 receptors.
Price Range : 1060.00 GBP - 2680.00 GBP
Adenosine 5 Triphosphate 250 µCi

Imipramine Hydrochloride, [Benzene ring-3H(N)]-, 250µCi (9.25MBq)

Imipramine hydrochloride, tritiated on the benzene ring. Imipramine is believed to act as an antagonist at certain serotonin, histamine, and cholinergic receptors.
List Price : 1300.00 GBP
Adenosine 5 Triphosphate 250 µCi

R(+)7-HYDROXY DPAT, [3H], 250 µCi

Tritiated R(+)7-Hydroxy DPAT. 7-OH-DPAT acts as a selective agonist at the dopamine D3 receptor. It also has low affinity for serotonin receptors.
List Price : 2900.00 GBP
Diclofenac sodium- Phenylacetic acid C14

Iodoantipyrine, 4-[N-Methyl-14C]

4-Iodoantipyrine, labeled with C-14 on the N-methyl group. Iodoantipyrine has been used to measure cerebral blood flow.
Price Range : 620.00 GBP - 5080.00 GBP
Adenosine 5 Triphosphate 250 µCi

Pirenzepine, [N-Methyl-3H]

Pirenzepine, tritiated on the N-methyl group. Pirenzepine acts as a selective antagonist of the muscarinic M1 acetylcholine receptor.
Price Range : 1710.00 GBP - 4320.00 GBP
Adenosine 5 Triphosphate 250 µCi

Histamine Dihydrochloride, [Ring, Methylenes-3H(N)]

Histamine dihydrochloride, tritiated on the ring and methylene groups. Histamine is an endogenous agonist of histamine receptors.
Price Range : 950.00 GBP - 2630.00 GBP
Adenosine 5 Triphosphate 250 µCi

Methyl-4-Phenylpyridinium Acetate, N-[Methyl-3H]-, MPP (+)

N-Methyl-4-phenylpyridinium (MPP+) acetate, tritiated on the methyl group. MPP+ is a substrate for the organic cation ion transporter (OCT), the dopamine transporter (DAT), the norepinephrine transporter (NET), and the serotonin transporter (SERT).
Price Range : 450.00 GBP - 1200.00 GBP
Adenosine 5 Triphosphate 250 µCi

Diprenorphine [15,16-3H]

Diprenorphine (Revivon; M5050; diprenorfin), tritiated at the 15,16- position. Diprenorphine acts as a non-selective antagonist at opioid receptors.
Price Range : 524.00 GBP - 1490.00 GBP
Adenosine 5 Triphosphate 250 µCi

MK-801, (+)-[3-3H]-

(+)-MK-801 radioligand tritriated at the 3 position. MK-801 acts as a non-competitive antagonist at the glutamate receptor, N-Methyl-D-aspartate (NMDA).
Price Range : 570.00 GBP - 4010.00 GBP
Adenosine 5 Triphosphate 250 µCi

Flunitrazepam, [Methyl-3H]

Flunitrazepam (Rohypnol), tritiated on the methyl group. Flunitrazepam is a benzodiazepine and acts as an agonist at GABAA (γ-aminobutyric acid) receptors.
Price Range : 465.00 GBP - 4660.00 GBP
Adenosine 5 Triphosphate 250 µCi

CP 55940, [Side Chain-2,3,4-3H(N)]

CP 55,940, tritiated on the side chain-2,3-4 position. CP 55,940 is a synthetic cannabinoid that acts as a full agonist at both cannabinoid CB1 and CB2 receptors, and can also upregulate serotonin 5-HT2A receptors.
Price Range : 588.00 GBP - 4910.00 GBP
Adenosine 5 Triphosphate 250 µCi

5-Hydroxytryptamine Creatinine Sulfate, [1,2-3H(N)]

5-Hydroxytryptamine Creatinine Sulfate (Serotonin, 5-HT), tritiated at the 1,2 position. 5-Hydroxytryptamine is a neurotransmitter and is the endogenous ligand for serotonin receptors.
Price Range : 656.00 GBP - 1770.00 GBP

QUISQUALIC ACID, [3H]

Quisqualic acid, tritiated. Quisqualic acid acts as an agonist at AMPA receptors, kainate receptors, and group 1 metabotropic glutamate receptors.
List Price : 2100.00 GBP
Diclofenac sodium- Phenylacetic acid C14

DICLOFENAC SODIUM[PHENYLACETIC ACID RING- U-14C]

Diclofenac sodium, labeled with C-14 on the phenylacetic acid ring. Diclofenac is a nonsteroidal anti-inflammatory drug (NSAID) that acts as an antagonist at peroxisome prolifeator-activated receptor gamma (PPAR-γ or PPARG).
List Price : 2060.00 GBP
Adenosine 5 Triphosphate 250 µCi

Scopolamine Methyl Chloride, [N-methyl-3H]

Scopolamine methyl chloride, tritiated on the N-methyl group. Scopolamine acts as an antagonist at muscarinic acetylcholine receptors.
Price Range : 1330.00 GBP - 3050.00 GBP
Adenosine 5 Triphosphate 250 µCi

DOFETILIDE, [N-METHYL-3H], 100 µCi

Dofetilide, tritiated at the N-methyl position. Dofetilide is a selective potassium channel (hERG) blocker.
List Price : 1390.00 GBP
Adenosine 5 Triphosphate 250 µCi

Dihydroalprenolol Hydrochloride, Levo-[Ring, Propyl-3H(N)]

Dihydroalprenolol hydrochloride, tritiated on the ring propyl group. Dihydroalprenolol (DHA) is an alprenolol derivative that binds to beta-adrenergic receptors and acts as a beta-adrenergic blocker.
Price Range : 862.00 GBP - 1960.00 GBP
Adenosine 5 Triphosphate 250 µCi

Astemizole, [O-Methyl-3H]

Astemizole (Hismanal) tritiated at the O-methyl group. Atemizole is an antagonist of the histamine H1-receptor and has been shown to block hERG potassium channels.
Price Range : 616.00 GBP - 6970.00 GBP
Adenosine 5 Triphosphate 250 µCi

PK 11195, [N-Methyl-3H]

PK-11195, tritiated on the N-methyl group. PK-11195 binds selectively to the peripheral benzodiazepine receptor (PBR).
Price Range : 1760.00 GBP - 3940.00 GBP
Adenosine 5 Triphosphate 250 µCi

NALOXONE, [N-ALLYL-2,3-3H]-

Naloxone radioligand tritiated at the 2,3 position. Naloxone acts as a non-selective, competitive opioid receptor antagonist.
List Price : 1570.00 GBP
Adenosine 5 Triphosphate 250 µCi

Dihydroxyphenylethylamine [2,5,6,7,8-3H] (Dopamine)

Dihydroxyphenylethylamine (dopamine) radioligand tritiated at the 2,5,6,7,8 position. Dopamine functions as a neurotransmitter that binds dopamine receptors.
List Price : 2390.00 GBP

Ro 15-1788, [N-Methyl-3H]

Ro 15-1788 (flumazenil), tritiated on the N-methyl group. Ro 15-1788 acts as a selective benzodiazepine antagonist.
Price Range : 1890.00 GBP - 4270.00 GBP

MK-912, [3H(G)]

MK-912 radioligand. MK-912 acts as a selective antagonist at the α2-adrenoceptor. This product has a scheduled lot release for the second Monday in October. NOTE: NET1227025UC will be obsoleted soon.
List Price : 2770.00 GBP
Adenosine 5 Triphosphate 250 µCi

SPIPERONE, [3H]

Tritiated Spiperone. Spiperone acts as an antagonist at Dopamine D2 and D3 receptors, 5-HT1A, 5-HT2A, and alpha-adrenergic receptors (α adrenoreceptors).
List Price : 1890.00 GBP
Adenosine 5 Triphosphate 250 µCi

Rauwolscine, [Methyl-3H]-, 250µCi (9.25MBq)

Rauwolscine, tritiated on the methyl group. Rauwolscine acts as an antagonist at α2-adrenergic receptors.
List Price : 1650.00 GBP
Adenosine 5 Triphosphate 250 µCi

DAMGO, [Tyrosyl-3,5-3H(N)]

DAMGO, tritiated at the tyrosyl 3,5 poisition. DAMGO is a synthetic opioid analog with high specificity for the μ-opioid receptor.
Price Range : 1510.00 GBP - 3910.00 GBP
Adenosine 5 Triphosphate 250 µCi

Prazosin, [7-Methoxy-3H]

Prazosin, tritiated at the 7-methoxy position. Prazosin acts as an inverse agonist at the α1-adrenergic receptor.
Price Range : 614.00 GBP - 4850.00 GBP
Diclofenac sodium- Phenylacetic acid C14

Caffeine, [1-Methyl-14C]-, 50µCi (1.85MBq)

Caffeine, radiolabeled with C-14 at the 1-methyl position. Caffeine acts as a non-selective antagonist at adenosine receptors.
List Price : 717.00 GBP
Adenosine 5 Triphosphate 250 µCi

Muscimol, 3-Hydroxy-5-Aminomethylisoxazole, [Methylene-3H(N)]

3H Muscimol radioligand. Muscimol acts as a potent selective agonist at GABAA receptors. It also acts as a partial agonist at GABAA-rho receptors. This product has a scheduled lot release for the second Monday in February and August. NOTE: NET574001MC will be obsolete soon.
List Price : 1540.00 GBP
Adenosine 5 Triphosphate 250 µCi

(+)-Pentazocine, [Ring-1,3-3H]

(+)-Pentazocine radioligand tritiated at the 1,3 position on the ring. Pentazocine is a synthetic opioid shown to bind sigma 1 receptor.
Price Range : 546.00 GBP - 4260.00 GBP
Adenosine 5 Triphosphate 250 µCi

Glibenclamide, Glyburide, [Cyclohexyl-2,3-3H(N)]-, 250µCi (9.25MBq)

Glibenclamide (glyburide) tritiated at the cyclohexyl-2,3 position. Glibenclamide is an antidiabetic drug that binds and inhibits the ATP-sensitive potassium channel.
List Price : 2540.00 GBP
Adenosine 5 Triphosphate 250 µCi

Norepinephrine Hydrochloride, DL-[7-3H(N)]-, 250µCi (9.25MBq)

DL-Norepinephrine hydrochloride, tritiated at the 7 position. Norepinephrine binds and activates adrenergic receptors, and is cleared by the norepinehprine transporter (NET).
List Price : 1010.00 GBP
Adenosine 5 Triphosphate 250 µCi

MELATONIN, [0-METHYL-3H]

Melatonin, tritiated on the o-methyl group. Melatonin is the endogenous ligand that binds and activates melatonin receptors.
List Price : 2310.00 GBP

"Ligands" 1-50 of 116 Products & Services

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